Möglichkeiten zur Nutzung der autokatalytischen RNA-Replikation von Pflanzenviren für die Expressionsoptimierung von Fremdgenen

Allison, R. F., M. Janda, P. Ahlquist, 1988: Infectiousin vitro transcripts from cowpea chlorotic mottle virus cDNA clones and exchange of individual RNA components with brome mosaic virus. — J. Virol.62, 3581–3588. Bujarski, J. J., T. W. Dreher, T. C. Hall, 1985: Deletions in the 3′terminal tRNA-like structure of viral RNA differentially affect aminoacylation and replicationin vitro. Proc. Natl. Acad. Sci. USA82, 5636–5640. ——, 1982: Use of dodecyl-β-D-maltoside in the purification and stabilization of RNA polymerase from brome mosaic virus- infected barley. — Virology119, 465–473. Dawson, W. O., D. J. Lewandowski, M. E. Hilf, P. Bubrick, A. J. Raffo, J. J. Shaw, G. L. Grantham, P. R. Desjardins, 1989: A tobacco mosaic virus-hybrid expresses and loses an added gene. — Virology172, 285–292. Dreher, T. W., T. C. Hall, 1987: RNA replication of brome mosaic virus and related viruses. — In: RNA Genetics. Vol. 1,J. H. Holland, D. Esteban, P. Ahlquist, Eds. Boca Raton, CRC Press, Florida, 91–113. Dzianott, A., J. J. Bujarski, 1989: Derivation of an infectious viral RNA by autocatalytic cleavage ofin vitro transcribed viral cDNAs. — Proc. Natl. Acad. Sci. USA86, 4823–4827. Fraenkel-Conrat, H., 1983: RNA-dependent RNA polymerases of plants. — Proc. Nat. Acad. Sci. USA,80, 422–424. French, R., P. Ahlquist, 1987: Intercistronic as well as terminal sequences are required for efficient amplification of brome mosaic virus RNA3. — J. Virol.61, 1457–1465. —— ——, 1988: Characterization and engineering of sequences controllingin vivo synthesis of brome mosaic virus subgenomic RNA. — J. Virol.62, 2411–2420. ——, 1986: Bacterial gene inserted in an engineered RNA virus: efficient expression in monocotyledonous plant cells. — Science231, 1294–1297. Gorbalenya A. E., E. V. Koonin, A. P. Donchenko, V. M. Blinov, 1988: A conserved NTP-motif in putative helicases. — Nature333, 22. Hall, T. C., T. W. Dreher, L. E. Marsh, 1987: Replicase and replication: Strategies for brome mosaic virus. — In: Molecular Strategies for Crop Protection, Alan R. Liss, Inc., 295–305. Hardy, S. F., T. L. German, L. S. Loesch-Fries, T. C. Hall, 1979: Highly active template specific RNA-dependent RNA polymerase from barley leaves infected with brome mosaic virus. — Proc. Natl. Acad. Sci. USA76, 4956–5960. Hodgman, T. C., 1988: A new superfamily of replicative proteins. — Nature333, 22–23. Horikoshi, M., K. Mise, I. Furusawa, J. Shishiyama, 1988: Immunological analysis of brome mosaic virus replicase. — J. gen. Virol.69, 3081–3087. Ishikawa, M., T. Meshi, Y. Watanabe, Y. Okada, 1988: Replication of chimeric tobacco mosaic viruses which carry heterologous combinations of replicase genes and 3′noncoding regions. — Virology164, 290–293. Kamer, G., P. Argos, 1984: Primary structural comparison of RNA-dependent polymerase from plant, animal and bacterial viruses. — Nucl. Acids Res.12, 7269–7282. Kiberstis, P. A., L. S. Loesch-Fries, T. C. Hall, 1981: Viral protein synthesis in barley protoplasts inoculated with native and fractionated brome mosaic virus RNA. — Virology112, 804–808. Loesch-Fries, L. S., T. C. Hall, 1980: Synthesis, accumulation and encapsidation of individual brome mosaic virus RNA components in barley protoplasts. — J. gen. Virol.47, 323–332. —— ——, 1982:In vivo aminoacylation of brome mosaic and barley stripe mosaic virus RNAs. — Nature298, 771–772. Marsh L. E., T. W. Dreher, T. C. Hall, 1987: Mutational analysis of the internal promotor for transcription of the subgenomic RNA4 of BMV. — In: Proc. UCLA Symp. Positive Strand RNA Viruses.Brinton, M. A. andRueckert, R., Eds., Alan R. Liss, New York, 327–336. ——, 1987: Evidence implicating a tRNA heritage for the promotors of positive-strand RNA synthesis in brome mosaic and related viruses. — Cold Spring Harbor Symp. Quant. Biol., Vol.LII, 331–341. Miller, W. A., J. J. Bujarski, T. W. Dreher, T. C. Hall, 1986: Minusstrand initiation by brome mosaic virus replicase within the 3′tRNA-like structure of native and modified RNA templates. — J. molec. Biol.187, 537–546. ——, 1985: Synthesis of brome mosaic virus subgenomic RNAin vitro by internal initiation on (−)-sense genomic RNA. — Nature313, 68–70. ——, 1983: Use of micrococcal nuclease in the purification of highly template-dependent RNA-dependent RNA polymerase from brome mosaic virus-infected barley. — Virology125, 236–241. Mills, D. R., 1988: Engineered recombinant messenger RNA can be replicated and expressed inside bacterial cells by an RNA bacteriophage replicase. — J. Mol. Biol.200, 489–500. Perret, V., C. Florentz, T. Dreher, R. Giege, 1989: Structural analogies between the 3'tRNA-like structure of brome mosaic virus RNA and yeast tRNATyr revealed by protection studies with yeast tyrosyl-tRNA synthetase. — Eur. J. Biochem.185, 331–339. Quadt, R., H. J. M. Verbeek, E. M. J. Jaspars, 1988: Involvement of a nonstructural protein in the RNA synthesis of brome mosaic virus. — Virology165, 256–261. Sharp, S. J., J. Shaack, L. Cooley, D. J. Burke, D. Söll, 1985: Structure and transcription of eucaryotic tRNA genes. — CRC Crit. Rev. Biochem.19, 107–144. Symons, R. H., 1985: Viral genome structure. — In: The Plant Viruses. Polyhedral Virions with Tripartite Genomes. Vol. 1.Francki, R. I. B., Ed. Plenum Press, New York, 57–81. Takamatsu, N., M. Ishikawa, T. Meshi, Y. Okada, 1987: Expression of bacterial chloramphenicol acetyltransferase gene in tobacco plants mediated by TMV-RNA. — Embo J.6, 307–311. Yamaya, J., M. Yoshioka, T. Meshi, Y. Okada, T. Ohno, 1988: Expression of tobacco mosaic virus RNA in transgenic plants. — Mol. Gen. Genet.211, 520–525.