Lymphovascular space invasion and estrogen receptor status in high-grade serous ovarian cancer – A multicenter study by the FRANCOGYN group

Jerome Lorenzini1, Marion Deberti1, Gilles Body1,2, Xavier Carcopino3, Cyril Touboul4, Yohann Dabi4, Pierre Collinet5, Charles Coutant6, Cherif Akladios7, Vincent Lavoué8, Pierre-Adrien Bolze9, Cyrille Huchon10, Alexandre Bricou11, Geoffroy Canlorbe12, Camille Mimoun13, Sofiane Bendifallah14, Lobna Ouldamer1,2
1Department of Gynecology, Service de Gynécologie, Tours University Hospital, 2 Boulevard Tonnellé, Tours 37044, France
2INSERM U1069, Université François-Rabelais, Tours, France
3Department of Obstetrics and Gynecology, Hôpital Nord, APHM, Aix-Marseille University (AMU), Univ Avignon, CNRS, IRD, IMBE UMR 7263, 13397, Marseille, France
4Department of Obstetrics and Gynecology, Centre Hospitalier Intercommunal, Creteil, France
5Department of Gynecologic surgery, Jeanne de Flandre Hospital, CHRU LILLE, Rue Eugene Avinée 59037 Lille Cedex, France
6Department of Surgical Oncology, Georges-Francois Leclerc Cancer Centre, Dijon, France
7Department of Surgical Gynecology, Strasbourg University Hospital, Strasbourg, France
8Department of Gynecology, Rennes University Hospital, France. INSERM 1242, COSS, Rennes. Université de Rennes 1. France
9Department of Gynecologic and Oncologic Surgery and Obstetrics, Lyon Sud University Hospital, Hospices Civils de Lyon, Université Lyon 1, France
10Department of Gynecology, CHI Poissy-St-Germain, Université Versailles-Saint-Quentin en Yvelines, EA 7285 Risques cliniques et sécurité en santé des femmes, Université Versailles-Saint-Quentin en Yvelines, Versailles, France
11Department of Gynecology, Bobigny University, AP-HP, Jean-Verdier Hospital, Bondy, France
12Department of Gynecologic and Breast Surgery and Oncology, AP-HP, Pitié-Salpêtrière University Hospital, Paris, France
13Department of Gynecology and Obstetrics, Lariboisiere Hospital, 750019 Paris, France
14Department of Gynecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France

Tài liệu tham khảo

Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J Clin, 68, 394, 10.3322/caac.21492 Kurman, 2014, WHO classification of tumours of ovary, 12 Guntupalli, 2012, Lymphovascular space invasion is an independent risk factor for nodal disease and poor outcomes in endometrioid endometrial cancer, Gynecol Oncol, 124, 31, 10.1016/j.ygyno.2011.09.017 Watanabe, 2010, Evaluation of parametrial spread in endometrial carcinoma, Obstet Gynecol, 116, 1027, 10.1097/AOG.0b013e3181f80a49 O'Brien, 2009, Lymphovascular space involvement in early stage well-differentiated endometrial cancer is associated with increased mortality, BJOG Int J Obstet Gynaecol, 116, 991, 10.1111/j.1471-0528.2009.02162.x Matsuo, 2015, Impact of depth and extent of lymphovascular space invasion on lymph node metastasis and recurrence patterns in endometrial cancer, J Surg Oncol, 112, 669, 10.1002/jso.24049 Chernofsky, 2006, Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix, Gynecol Oncol, 100, 288, 10.1016/j.ygyno.2005.08.019 Memarzadeh, 2003, Lymphovascular and perineural invasion in the parametria: a prognostic factor for early-stage cervical cancer, Obstet Gynecol, 102, 612 Lim, 2008, Clinical value of immunohistochemically detected lymphovascular space invasion in early stage cervical carcinoma, Ann Surg Oncol, 15, 2581, 10.1245/s10434-008-0014-z Morice, 2003, Prognostic value of lymphovascular space invasion determined with hematoxylin-eosin staining in early stage cervical carcinoma: results of a multivariate analysis, Ann Oncol Off J Eur Soc Med Oncol, 14, 1511, 10.1093/annonc/mdg412 Raspagliesi, 2006, Clinical and pathological prognostic factors in squamous cell carcinoma of the vulva, Gynecol Oncol, 102, 333, 10.1016/j.ygyno.2005.12.027 Rouzier, 2006, Development and validation of a nomogram for predicting outcome of patients with vulvar cancer, Obstet Gynecol, 107, 672, 10.1097/01.AOG.0000198639.36855.e9 Cheng, 2009, Recurrence patterns and prognostic factors in Chinese patients with squamous cell carcinoma of the vulva treated with primary surgery, Int J Gynecol Cancer Off J Int Gynecol Cancer Soc, 19, 158, 10.1111/IGC.0b013e3181996a78 Matsuo, 2014, Effect of lymphovascular space invasion on survival of stage I epithelial ovarian cancer, Obstet Gynecol, 123, 957, 10.1097/AOG.0000000000000240 Matsuo, 2012, Significance of lymphovascular space invasion in epithelial ovarian cancer, Cancer Med, 1, 156, 10.1002/cam4.31 Matsuo, 2015, Survival outcome of stage I ovarian clear cell carcinoma with lympho-vascular space invasion, Gynecol Oncol, 136, 198, 10.1016/j.ygyno.2014.12.006 Matsuo, 2014, Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma, Gynecol Oncol, 133, 473, 10.1016/j.ygyno.2014.03.563 Qian, 2010, The grading of lymphovascular space invasion in epithelial ovarian carcinoma, Int J Gynecol Cancer Off J Int Gynecol Cancer Soc, 20, 895, 10.1111/IGC.0b013e3181e02fc7 Chen, 2015, Prognostic significance of lymphovascular space invasion in epithelial ovarian cancer, J Cancer, 6, 412, 10.7150/jca.11242 Li, 2017, Increased risk of poor survival in ovarian cancer patients with high expression of SNAI2 and lymphovascular space invasion, Oncotarget, 8, 9672, 10.18632/oncotarget.14192 Masoumi-Moghaddam, 2015, Sprouty 1 predicts prognosis in human epithelial ovarian cancer, Am J Cancer Res, 5, 1531 Mvunta, 2017, Overexpression of SIRT1 is associated with poor outcomes in patients with ovarian carcinoma, Appl Immunohistochem Mol Morphol AIMM, 25, 415, 10.1097/PAI.0000000000000316 McCluggage, 2015, Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR), Mod Pathol Off J U S Can Acad Pathol Inc, 28, 1101 Matsuo, 2017, Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma, J Surg Oncol Shih, 2004, Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis, Am J Pathol, 164, 1511, 10.1016/S0002-9440(10)63708-X Köbel, 2008, (2008) Ovarian carcinoma subtypes are different diseases: implications for biomarker studies, PLoS Med, 5, e232, 10.1371/journal.pmed.0050232 Sieh, 2013, Associations between hormone receptor expression and ovarian cancer survival: an ovarian tumor tissue analysis consortium study, Lancet Oncol, 853, 10.1016/S1470-2045(13)70253-5 Liu, 2009, Prognosis and hormone receptor status in older and younger patients with advanced-stage papillary serous ovarian carcinoma, Gynecol Oncol, 115, 401, 10.1016/j.ygyno.2009.08.023 Chuffa, 2017, The role of sex hormones and steroid receptors on female reproductive cancers, Steroids, 118, 93, 10.1016/j.steroids.2016.12.011 Tkalia, 2014, Clinical significance of hormonal receptor status of malignant ovarian tumors, Exp Oncol., 36, 125 Spannuth, 2008, Angiogenesis as a strategic target for ovarian cancer therapy, Nat Clin Pract Oncol, 5, 194, 10.1038/ncponc1051 Botting, 2010, Prognostic significance of peritumoral lymphatic vessel density and vascular endothelial growth factor receptor 3 in invasive squamous cell cervical cancer, Transl Oncol, 3, 170, 10.1593/tlo.09292 Chen, 2017, The positivity of estrogen receptor and progesterone receptor may not be associated with metastasis and recurrence in epithelial ovarian cancer, Sci Rep, 7, 16922, 10.1038/s41598-017-17265-6 Yokoyama, 2013, Recurrent epithelial ovarian cancer and hormone therapy, World J Clin Cases, 1, 187, 10.12998/wjcc.v1.i6.187 Feng, 2017, Hormone receptor expression profiles differ between primary and recurrent high-grade serous ovarian cancers, Oncotarget, 8, 32848, 10.18632/oncotarget.15858 Shen, 2017, Correlation between estrogen receptor expression and prognosis in epithelial ovarian cancer: a meta-analysis, Oncotarget, 8, 62400, 10.18632/oncotarget.18253