Low vegetable intake is associated with allergic asthma and moderate‐to‐severe airway hyperresponsiveness

Pediatric Pulmonology - Tập 47 Số 12 - Trang 1159-1169 - 2012
Jennifer L. P. Protudjer1, Gustaaf P. Sevenhuysen1, Clare D. Ramsey1, Anita L. Kozyrskyj2,1, Allan B. Becker1
1University of Manitoba, Manitoba, Canada
2University of Alberta, Alberta, Canada

Tóm tắt

AbstractBackgroundIn recent decades, children's diet quality has changed and asthma prevalence has increased, although it remains unclear if these events are associated.ObjectiveTo examine children's total and component diet quality and asthma and airway hyperresponsiveness (AHR), a proxy for asthma severity.MethodsFood frequency questionnaires adapted from the Nurses' Health Study and supplemented with foods whose nutrients which have garnered interest of late in relation to asthma were administered. From these data, diet quality scores (total and component), based on the Youth Healthy Eating Index (YHEI adapted) were developed. Asthma assessments were performed by pediatric allergists and classified by atopic status: Allergic asthma (≥1 positive skin prick test to common allergens >3 mm compared to negative control) versus non‐allergic asthma (negative skin prick test). AHR was assessed via the Cockcroft technique. Participants included 270 boys (30% with asthma) and 206 girls (33% with asthma) involved in the 1995 Manitoba Prospective Cohort Study nested case‐control study. Logistic regression was used to examine associations between diet quality and asthma, and multinomial logistic regression was used to examine associations between diet quality and AHR.ResultsFour hundred seventy six children (56.7% boys) were seen at 12.6 ± 0.5 years. Asthma and AHR prevalence were 26.2 and 53.8%, respectively. In fully adjusted models, high vegetable intake was protective against allergic asthma (OR 0.49; 95% CI 0.29–0.84; P < 0.009) and moderate/severe AHR (OR 0.58; 0.37–0.91; P < 0.019).ConclusionsVegetable intake is inversely associated with allergic asthma and moderate/severe AHR. Pediatr Pulmonol. 2012; 47:1159–1169. © 2012 Wiley Periodicals, Inc.

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Tài liệu tham khảo

Garner R, 2008, Changes in the prevalence of asthma among Canadian children, Health Rep, 19, 45

10.1038/sj.ijo.0802804

Venes D, 2001, Taber's cyclopedic medical dictionary

10.1016/j.jada.2010.10.048

Mertz W, 1984, Foods nutrients, J Am Diet Assoc, 84, 769, 10.1016/S0002-8223(21)08242-0

10.1016/S0002-8223(96)00217-9

10.1111/j.1398-9995.2009.02267.x

10.1164/rccm.200710-1544OC

10.1111/j.1365-2222.2010.03672.x

10.1093/ajcn/84.4.903

10.1093/ajcn/78.3.414

10.1136/thx.2006.074534

10.1093/ajcn/86.2.488

10.1111/j.1398-9995.2009.02215.x

10.1111/j.1365-2222.2006.02627.x

10.1136/thx.52.2.166

Liu HM, 1972, A retrospective study on bronchial asthma in Shulin township, Taipei County, Taiwan J Formos Med Assoc, 71, 493

10.1093/ajcn/59.5.1171S

10.1513/pats.200808-092RM

10.1016/S0091-6749(00)90049-6

10.1378/chest.123.3_suppl.411S

10.1111/j.1398-9995.2009.02033.x

BayonaM OlsenC. Observational studies and bias in epidemiology. Available on‐line on 16 December 2011 at:http://www.collegeboard.com/prod_downloads/yes/4297_MODULE_19.pdf.

10.1016/j.jada.2004.06.020

United States Department of Agriculture. My Pyramid.2005. Available on‐line at:www.mypyramid.gov.

2007, Health Canada. Eating well with Canada's Food Guide

Willett W, 1990, Nutritional epidemiology

10.1017/S0007114507868516

10.1093/aje/kwi019

10.1097/ACI.0b013e32832b36cd

10.1378/chest.07-0038

10.1016/j.nut.2004.06.027

10.1111/j.1399-3038.2006.00474.x

10.1136/thorax.55.7.562

10.1111/j.1399-3038.2007.00596.x

10.1111/j.1365-2222.1977.tb01448.x

Canadian Pediatric Society, 2004, The use of growth charts for assessing and monitoring growth in Canadian infants and children, Pediatr Child Health, 9, 171, 10.1093/pch/9.3.171

10.3109/02770903.2011.555039

10.1136/thx.2009.128256

10.1080/02770900802553128

10.1136/thx.2004.039123

10.1111/j.1651-2227.2005.tb01882.x

10.3945/ajcn.2009.29021

10.1111/j.1750-3841.2009.01091.x

10.1093/ije/dyi245

10.1017/S1368980009990292

10.1378/chest.103.1.151

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Pediatric Pulmonology

Tập 47 Số 12

1159-1169

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