Low-contrast-dose protocol in cardiac CT: 20% contrast dose reduction using 100 kVp and high-tube-current-time setting in 256-slice CT

Acta Radiologica - Tập 55 Số 5 - Trang 545-553 - 2014
Masafumi Kidoh1,2, Takeshi Nakaura1,2, Shinichi Nakamura1,2, Shota Nakamura3, Naritsugu Sakaino3, Kazunori Harada4, Sachiko Uemura5, Yasuyuki Yamashita1
1Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Japan
2Diagnostic Radiology, Amakusa Medical Center, Kumamoto, Japan
3Department of Cardiology, Amakusa Medical Center, Kumamoto, Japan
4Department of Surgery, Amakusa Medical Center, Kumamoto, Japan
5Department of Neurosurgery, Amakusa Medical Center, Kumamoto, Japan

Tóm tắt

Background The use of the smallest contrast dose is highly desirable in performing cardiac computed tomography (CT), especially for patients with cardiovascular diseases to prevent contrast-induced nephropathy. Purpose To evaluate the feasibility of 20% reduced contrast dose protocol in cardiac CT using 100 kVp and high-tube-current-time product setting. Material and Methods Fifty patients were scanned with our conventional 120 kVp protocol, and the other 50 patients underwent scans using a tube voltage of 100 kVp, a high-tube-current-time product, and a 20% reduced contrast dose. We evaluated estimated effective dose (ED), CT attenuation, image noise, and contrast-to-noise ratio (CNR) of the ascending aorta. We also evaluated CT attenuation of the coronary arteries. Two radiologists independently assessed image quality of coronary arteries. Results There was no significant difference in the ED between the 100 kVp and 120 kVp protocols (21.7 mSv ± 1.6 vs. 21.8 mSv ± 1.1, P = 0.65). There was no significant difference in the CNR of the ascending aorta between the 100 kVp and 120 kVp protocols (18.8 ± 3.5 vs. 18.7 ± 3.8, P = 0.98). Mean CT attenuation of the coronary arteries of the 100 kVp protocols was significantly higher than that of 120 kVp protocols ( P < 0.05). There was no significant difference in the overall image quality of the coronary artery between the 100 kVp and 120 kVp protocols (3.7 ± 0.4 vs. 3.7 ± 0.5, P = 0.65). Conclusion For cardiac CT a voltage setting of 100 kVp and a high-tube-current-time product enable 20% reduction in the contrast dose without affecting the quality of coronary artery images compared with a 120 kVp and standard-contrast-dose CT protocol.

Từ khóa


Tài liệu tham khảo

10.4065/83.10.1095

10.1016/S0002-9343(97)00150-2

10.1016/S0735-1097(00)00917-7

10.1258/ar.2011.100395

10.1016/j.jcmg.2009.02.015

10.1007/s10554-010-9754-5

Huda W, 2004, Medical Imaging, 5368, 499

10.1148/radiol.2373041655

10.2214/AJR.05.0471

10.1148/radiology.217.2.r00nv35430

10.3109/02841851.2010.504740

10.1161/CIRCULATIONAHA.105.602490

10.1148/radiol.11110021

10.1148/radiol.2513081330

10.1007/s003300050674

10.1148/radiol.09090094

10.1148/radiol.10092016

10.1016/j.jcmg.2010.08.016

10.1148/radiol.10090908

10.1097/RCT.0b013e31802d3dd2