Low adherence to antidepressants is associated with increased mortality following stroke: A large nationally representative cohort study

Ayerbe, 2014, Explanatory factors for the increased mortality of stroke patients with depression, Neurology, 83, 10.1212/WNL.0000000000001029 Ayerbe, 2013, Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis, Br. J. Psychiatry, 202, 14, 10.1192/bjp.bp.111.107664 Bailey, 2010, Antihypertensive medication adherence, ambulatory visits, and risk of stroke and death, J. Gen. Intern. Med., 25, 495, 10.1007/s11606-009-1240-1 Bartoli, 2013, Depression after stroke and risk of mortality: a systematic review and meta-analysis, Stroke Res. Treat., 2013, 862978 Charlson, 1987, A new method of classifying prognostic comorbidity in longitudinal studies: development and validation, J. Chronic. Dis., 40, 373, 10.1016/0021-9681(87)90171-8 Correll, 2017, Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls, World Psychiatry, 16, 163, 10.1002/wps.20420 Cumming, 2016, The high prevalence of anxiety disorders after stroke, Am. J. Geriatr. Psychiatry, 24, 154, 10.1016/j.jagp.2015.06.003 Fournier, 2010, Antidepressant drug effects and depression severity: a patient-level meta-analysis, JAMA, 303, 47, 10.1001/jama.2009.1943 Hackett, 2005, Predictors of depression after stroke: a systematic review of observational studies, Stroke, 36, 2296, 10.1161/01.STR.0000183622.75135.a4 Hackett, 2005, Frequency of depression after stroke: a systematic review of observational studies, Stroke, 36, 1330, 10.1161/01.STR.0000165928.19135.35 Hannestad, 2011, The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis, Neuropsychopharmacology, 36, 2452, 10.1038/npp.2011.132 Jamison, 2016, Barriers to medication adherence for the secondary prevention of stroke: a qualitative interview study in primary care, Br. J. Gen. Pract., 66, e568, 10.3399/bjgp16X685609 Jenkins, 2016, Stroke patients and their attitudes toward mHealth monitoring to support blood pressure control and medication adherence, Mhealth, 2, 10.21037/mhealth.2016.05.04 Jorge, 2003, Mortality and poststroke depression: a placebo-controlled trial of antidepressants, Am. J. Psychiatry, 160, 1823, 10.1176/appi.ajp.160.10.1823 Jorgensen, 2016, Incidence of depression after stroke, and associated risk factors and mortality outcomes, in a large cohort of Danish patients, JAMA Psychiatry, 73, 1032, 10.1001/jamapsychiatry.2016.1932 Karve, 2009, Good and poor adherence: optimal cut-point for adherence measures using administrative claims data, Curr. Med. Res. Opin., 25, 2303, 10.1185/03007990903126833 Kouwenhoven, 2011, Depression in acute stroke: prevalence, dominant symptoms and associated factors. A systematic literature review, Disabil. Rehabil., 33, 539, 10.3109/09638288.2010.505997 Krivoy, 2015, Adherence to antidepressant therapy and mortality rates in ischaemic heart disease: cohort study, Br. J. Psychiatry, 206, 297, 10.1192/bjp.bp.114.155820 Krivoy, 2016, Adherence to antidepressants is associated with lower mortality: a 4-year population-based cohort study, J. Clin. Psychiatry, 77, e566, 10.4088/JCP.14m09531 Mead, 2013, Selective serotonin reuptake inhibitors for stroke recovery: a systematic review and meta-analysis, Stroke, 44, 844, 10.1161/STROKEAHA.112.673947 Mikami, 2011, Increased frequency of first-episode poststroke depression after discontinuation of escitalopram, Stroke, 42, 3281, 10.1161/STROKEAHA.111.626507 Mitchell, 2017, Prevalence and predictors of post-stroke mood disorders: a meta-analysis and meta-regression of depression, anxiety and adjustment disorder, Gen. Hosp. Psychiatry, 47, 48, 10.1016/j.genhosppsych.2017.04.001 Mortensen, 2015, Early antidepressant treatment and all-cause 30-day mortality in patients with Ischemic stroke, Cerebrovasc. Dis., 40, 81, 10.1159/000435819 Mortensen, 2013, Post stroke use of selective serotonin reuptake inhibitors and clinical outcome among patients with ischemic stroke: a nationwide propensity score-matched follow-up study, Stroke, 44, 420, 10.1161/STROKEAHA.112.674242 Nunes, 2016, Multimorbidity and mortality in older adults: a systematic review and meta-analysis, Arch. Gerontol. Geriatr., 67, 130, 10.1016/j.archger.2016.07.008 Price, 2011, Antidepressants for the treatment of depression in neurological disorders: a systematic review and meta-analysis of randomised controlled trials, J. Neurol. Neurosurg. Psychiatry, 82, 914, 10.1136/jnnp.2010.230862 Robinson, 2016, Post-stroke depression: a review, Am. J. Psychiatry, 173, 221, 10.1176/appi.ajp.2015.15030363 Singer, 2012, EMR-based medication adherence metric markedly enhances identification of nonadherent patients, Am. J. Manag. Care, 18, e372 Tan, 2015, Efficacy and safety of Citalopram in treating post-stroke depression: a meta-analysis, Eur. Neurol., 74, 188, 10.1159/000441446 Tsai, 2011, Prevention of poststroke depression with milnacipran in patients with acute ischemic stroke: a double-blind randomized placebo-controlled trial, Int. Clin. Psychopharmacol., 26, 263, 10.1097/YIC.0b013e32834a5c64 Turner-Stokes, 2002, Depression after stroke: a review of the evidence base to inform the development of an integrated care pathway. Part 1: diagnosis, frequency and impact, Clin. Rehabil., 16, 231, 10.1191/0269215502cr487oa van Mierlo, 2014, The influence of psychological factors on health-related quality of life after stroke: a systematic review, Int. J. Stroke, 9, 341, 10.1111/ijs.12149 Xu, 2016, Efficacy and feasibility of antidepressant treatment in patients with post-stroke depression, Medicine, 95, e5349, 10.1097/MD.0000000000005349