Low Frequency of Phlebographic Deep Vein Thrombosis After Laparoscopic Cholecystectomy—A Pilot Study

Clinical and Applied Thrombosis/Hemostasis - Tập 12 Số 4 - Trang 421-426 - 2006
Fredrik Lindberg1, Martin Björck2, Ib Rasmussen2, Rickard Nyman3, David Bergqvist2
1Department of Surgery, Umeå University Hospital, Umeå,
2Department of Surgery, Uppsala University Hospital, Uppsala, Sweden
3Department of Radiology, Uppsala University Hospital, Uppsala, Sweden

Tóm tắt

To investigate the rate of deep vein thrombosis (DVT) after laparoscopic surgery, 50 patients underwent bilateral phlebography 7-11 days after laparoscopic cholecystectomy (LC). All received thromboembolism prophylaxis, either low molecular weight heparin (LMWH) or dextran. Three patients were converted to open cholecystectomy. D-dimer was investigated preoperatively, on day 1 and on the day of phlebography. One asymptomatic DVT was found. One phlebogram was incomplete. Seven phlebograms were not optimal but of sufficient quality to rule out DVT. The frequency of DVT was thus 1 of 49 or 2.0% (95% confidence interval, 0-6.0%). No anticoagulants were prescribed after discharge. No patient developed late thromboembolic complications. D-dimer values increased significantly at day 1 and were further increased at the time of phlebography. The frequency of phlebographical DVTs thus seems to be low despite prophylaxis of questionable efficacy. The D-dimer values, however, suggest that the effects of LC on coagulation/fibrinolysis have a duration of longer than 1 week.

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Tài liệu tham khảo

10.1007/s004649900942

Kiudelis M, 2002, Zentralbl Chir, 11, 944, 10.1055/s-2002-35828

10.1007/s004640090048

10.1046/j.1365-2168.2001.01635.x

Wazz G, 2000, J Soc Laparoendosc Surg, 4, 291

Krasinski Z, 1998, Langenbecks Arch Chir, 115, 1105

10.1001/archsurg.133.9.967

Bounameaux H, 1997, Thromb Res, 86, 271, 10.1016/S0049-3848(97)00070-4

Baca I, 1997, Chirurg, 68, 1275, 10.1007/s001040050359

10.5694/j.1326-5377.1996.tb122233.x

Kopánski Z, 1996, Wien Klin Wochenschr, 108, 105

Caprini JA, 1995, Surg Endosc, 10, 324

10.1055/s-0038-1650252

Bergqvist D, 1990, Acta Chir Scand Suppl, 556, 36

10.1007/BF01655219

10.1097/00000658-198808000-00016

10.1378/chest.119.1_suppl.132S

10.1302/0301-620X.77B5.7559695

10.1007/BF01655669

10.1016/0022-4804(81)90156-6

10.1097/00000658-200002000-00007

Thông tin
Thông tin xuất bản

Clinical and Applied Thrombosis/Hemostasis

Tập 12 Số 4

421-426

Thông tin tác giả