Low Calcium Diet in Idiopathic Urolithiasis: A Risk Factor for Osteopenia as Great as in Primary Hyperparathyroidism

Wiley - Tập 65 Số 6 - Trang 560-563 - 1990
Michel Fuss1,2,3, Thierry Pepersack1,2,4, Philip J. Bergman5,1,2,6, T Hurard1,2,7, Jonathan Simon1,2,8, Jacques Corvilain1,2,9
1Department of Urology, Erasme Hospital, Brussels, Belgium
2Departments of Internal Medicine, Clinical Chemistry, Nuclear Medicine and Urology, Laboratory of Experimental Medicine, Brugmann Hospital
3M. Fuss, MD, Director, Department of Endocrinology and Metabolism, Brugmann Hospital.
4T. Pepersack, MD, Registrar, Department of Internal Medicine, Brugmann Hospital.
5Associate Director, Department of Nuclear Medicine, Brugmann Hospital.
6P. Bergmann, MD, Director, Department of Clinical Chemistry
7T. Hurard, MD, Registrar, Department of Urology, Brugmann Hospital.
8J. Simon, MD, Assistant Professor of Urology, Erasme Hospital.
9J. Corvilain, MD, Director, Laboratory of Experimental Medicine, Brugmann Hospital.

Tóm tắt

Summary— The bone mineral content of the radius was measured in 32 male renal stone formers, 18 of them presenting with idiopathic urolithiasis and 14 with primary hyperparathyroidism, a disease known to disturb bone metabolism. The idiopathic stone formers had been on regular treatment with a low calcium diet. The bone mineral content of the radius was reduced to a similar level in both groups of patients. The data suggest that idiopathic stone formers on a low calcium diet are at risk of osteopenia; the factors which could lead to a negative calcium balance included uncompensated renal hypercalciuria, hypophosphataemia and exaggerated serum levels of 1,25‐dihydroxyvitamin D. To treat idiopathic hypercalciuria, thiazide diuretics, which reduce the renal excretion of calcium and have been shown to be beneficial for bone, seem safer than a low calcium diet.

Từ khóa


Tài liệu tham khảo

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Thông tin xuất bản

Wiley

Tập 65 Số 6

560-563

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