Loss of the Ecdysteroid-Inducible E75A Orphan Nuclear Receptor Uncouples Molting from Metamorphosis in Drosophila

Developmental Cell - Tập 3 - Trang 209-220 - 2002
Michael Bialecki1, Alycia Shilton2, Caroline Fichtenberg2, William A. Segraves2, Carl S. Thummel1
1Howard Hughes Medical Institute, Department of Human Genetics, 15 North 2030 East, University of Utah, Salt Lake City, UT 84112 USA
2Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA

Tài liệu tham khảo

Adams, 2000, The genome sequence of Drosophila melanogaster, Science, 287, 2185, 10.1126/science.287.5461.2185 Andres, 1994, Methods for quantitative analysis of transcription in larvae and prepupae Andres, 1993, Molecular analysis of the initiation of insect metamorphosis, Dev. Biol., 160, 388, 10.1006/dbio.1993.1315 Aribi, 1997, 2-Deoxyecdysone is a circulating ecdysteroid in the beetle Zophobas atratus, Biochim. Biophys. Acta, 1335, 246, 10.1016/S0304-4165(96)00144-4 Ashburner, 1974, Temporal control of puffing activity in polytene chromosomes, Cold Spring Harb. Symp. Quant. Biol., 38, 655, 10.1101/SQB.1974.038.01.070 Bilder, 1995, Genomic regions required for morphogenesis of the Drosophila embryonic midgut, Genetics, 141, 1087, 10.1093/genetics/141.3.1087 Bodenstein, 1965, The postembryonic development of Drosophila Burmester, 1999, Ecdysone-regulation of synthesis and processing of fat body protein 1, the larval serum protein receptor of Drosophila melanogaster, Eur. J. Biochem., 262, 49, 10.1046/j.1432-1327.1999.00315.x Burtis, 1990, The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins, Cell, 61, 85, 10.1016/0092-8674(90)90217-3 Buszczak, 1999, Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila, Development, 126, 4581, 10.1242/dev.126.20.4581 Charles, 1998, Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster, Insect Biochem. Mol. Biol., 28, 131, 10.1016/S0965-1748(97)00107-0 Chavez, 2000, The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels, Development, 127, 4115, 10.1242/dev.127.19.4115 DiBello, 1991, The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers, Genetics, 129, 385, 10.1093/genetics/129.2.385 Fletcher, 1995, The Drosophila E74 gene is required for the proper stage- and tissue-specific transcription of ecdysone-regulated genes at the onset of metamorphosis, Development, 121, 1411, 10.1242/dev.121.5.1411 Fletcher, 1995, The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone, Development, 121, 1455, 10.1242/dev.121.5.1455 Freeman, 1999, The dare gene, Development, 126, 4591, 10.1242/dev.126.20.4591 Gilbert, 1996, Endocrine cascade in insect metamorphosis Guay, 1991, The ecdysone-induced puffing cascade in Drosophila salivary glands, Genetics, 129, 169, 10.1093/genetics/129.1.169 Hill, 1993, The reaction with polytene chromosomes of antibodies raised against Drosophila E75A protein, Insect Biochem. Mol. Biol., 23, 99, 10.1016/0965-1748(93)90087-9 Huet, 1993, Puffs and PCR, Development, 118, 613, 10.1242/dev.118.2.613 Karim, 1991, Ecdysone coordinates the timing and amounts of E74A and E74B transcription in Drosophila, Genes Dev., 5, 1067, 10.1101/gad.5.6.1067 Karim, 1992, Temporal coordination of regulatory gene expression by the steroid hormone ecdysone, EMBO J., 11, 4083, 10.1002/j.1460-2075.1992.tb05501.x Kiss, 1988, Interactions and developmental effects of mutations in the Broad-Complex of Drosophila melanogaster, Genetics, 118, 247, 10.1093/genetics/118.2.247 Kraminsky, 1980, Induction of translatable mRNA for dopa decarboxylase in Drosophila, Proc. Natl. Acad. Sci. USA, 77, 4175, 10.1073/pnas.77.7.4175 Mangelsdorf, 1995, The RXR heterodimers and orphan receptors, Cell, 83, 841, 10.1016/0092-8674(95)90200-7 Murata, 1996, Regulation of the EDG84A gene by FTZ-F1 during metamorphosis in Drosophila melanogaster, Mol. Cell. Biol., 16, 6509, 10.1128/MCB.16.11.6509 Pascual, 1995, Quantification of ecdysteroids by immunoassay, Z. Naturforsch. [C], 50, 862, 10.1515/znc-1995-11-1219 Restifo, 1986, An ecdysone-responsive puff site in Drosophila contains a cluster of seven differentially regulated genes, J. Mol. Biol., 188, 517, 10.1016/S0022-2836(86)80002-X Restifo, 1992, Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of internal tissues in Drosophila, Roux's Arch. Dev. Biol., 201, 221, 10.1007/BF00188753 Riddiford, 1993, Hormones and Drosophila development Russell, 1996, Ecdysone-regulated chromosome puffing in Drosophila melanogaster Russell, 1996, The Drosophila Eip78C gene is not vital but has a role in regulating chromosome puffs, Genetics, 144, 159, 10.1093/genetics/144.1.159 Segraves, W.A. (1988). Molecular and genetic analysis of the E75 ecdysone-responsive gene of Drosophila melanogaster. PhD thesis, Stanford University, Stanford, CA. Segraves, 1990, The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily, Genes Dev., 4, 204, 10.1101/gad.4.2.204 Shilton, A. (2001). The role of the ecdysone early response gene E75 in Drosophila development. PhD thesis, Yale University, New Haven, CT. Sliter, 1992, Developmental arrest and ecdysteroid deficiency resulting from mutations at the dre4 locus of Drosophila, Genetics, 130, 555, 10.1093/genetics/130.3.555 Stone, 1993, The Drosophila 78C early late puff contains E78, an ecdysone-inducible gene that encodes a novel member of the nuclear hormone receptor superfamily, Cell, 75, 307, 10.1016/0092-8674(93)80072-M Talbot, 1993, Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms, Cell, 73, 1323, 10.1016/0092-8674(93)90359-X Thomas, 1993, Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle, Nature, 362, 471, 10.1038/362471a0 Thummel, 1996, Flies on steroids—Drosophila metamorphosis and the mechanisms of steroid hormone action, Trends Genet., 12, 306, 10.1016/0168-9525(96)10032-9 Thummel, 2001, Molecular mechanisms of developmental timing in C. elegans and Drosophila, Dev. Cell, 1, 453, 10.1016/S1534-5807(01)00060-0 Thummel, 1990, Spatial and temporal patterns of E74 transcription during Drosophila development, Cell, 61, 101, 10.1016/0092-8674(90)90218-4 Venkatesh, 1997, Disruption of the IP3 receptor gene of Drosophila affects larval metamorphosis and ecdysone release, Curr. Biol., 7, 500, 10.1016/S0960-9822(06)00221-1 White, 1997, Coordination of Drosophila metamorphosis by two ecdysone-induced nuclear receptors, Science, 276, 114, 10.1126/science.276.5309.114 Woodard, 1994, A molecular mechanism for the stage specificity of the Drosophila prepupal genetic response to ecdysone, Cell, 79, 607, 10.1016/0092-8674(94)90546-0 Yamada, 2000, Temporally restricted expression of transcription factor βFTZ-F1, Development, 127, 5083, 10.1242/dev.127.23.5083 Yamamoto, 1976, Steroid receptors, Annu. Rev. Biochem., 45, 721, 10.1146/annurev.bi.45.070176.003445 Yao, 1992, Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation, Cell, 71, 63, 10.1016/0092-8674(92)90266-F Yao, 1993, Functional ecdysone receptor is the product of EcR and Ultraspiracle genes, Nature, 366, 476, 10.1038/366476a0