Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease

Thomas Arendt1, Volker Bigl1, A Arendt2, A Tennstedt3
1Department of Neurochemistry, Paul Flechsig Institute of Brain Research, Karl Marx University, Leipzig, German Democratic Republic
2Department of Neuropathology, Pathological Institute, Karl Marx University, Leipzig, German Democratic Republic
3Pathological Institute, District Hospital of Neurology and Psychiatry, Mühlhausen-Pfafferode, German Democratic Republic

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Antuono P, Sorbi S, Bracco L, Fusco T (1980) A discrete sampling technique in senile dementia of the Alzheimer type and alcoholic dementia: study of the cholinergic system. In: Amaducci L, Davison AN, Antuono P (eds) Aging of the brain and dementia. Raven Press, New York, pp 151?158

Averback P (1981) Lesions of the nucleus ansae peduncularis in neuropsychiatric disease. Arch Neurol 38:230?235

Bigl V, Woolf NJ, Butcher LL (1982) Cholinergic projections from the basal forebrain to frontal, parietal, temporal, occipital and cingulate cortices: a combined fluorescent tracer and acetylcholinesterase analysis. Brain Res Bull 8:727?750

Bird ED, Barnes J, Iversen LL, Spokes EG, Mackay AVP, Shepherd M (1977) Increased brain dopamine and reduced glutamic acid decarboxylase and choline acethyltransferase activity in schizophrenia and related psychoses. Lancet II:1157?1159

Bowen EP (1976) Behavioural alterations in patients with basal ganglia lesions. In: Yahr M (ed) The basal ganglia Raven Press, New York, pp 169?180

Bowen DM, Davison AN (1978) Changes in brain lysosomal activity, neurotransmitter-related enzymes, and other proteins in senile dementia. In: Katzman R, Terry RD, Bick KL (eds) Alzheimer's disease. Raven Press, New York, pp 421?424

Bowen DM, Smith CB, White P, Davidson AN (1976) Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain 99:459?496

Brockhaus H (1942) Vergleichend-anatomische Untersuchungen über den Basalkernkomplex. J Psychol Neurol 51:57?95

Buttlar-Brentano K von (1952) Pathohistologische Feststellungen am Basalkern Schizophrener. J Nerv Ment Dis 116:646?653

Buttlar-Brentano K von (1955) Das Parkinsonsyndrom im Lichte der lebensgeschichtlichen Veränderungen des Nucleus basalis. J Hirnforsch 2:55?76

Davies P, Maloney AJF (1976) Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet II:1403

Davis KL, Yesavage JA (1979) Brain acetylcholine and disorders of memory. In: Davis KL, Berger PA (eds) Brain acetylcholine and neuropsychiatric disease. Plenum Press, New York, pp 205?213

De Kosky ST, Bass NH (1980) Effects of aging and senile dementia on the microchemical pathology of human cerebral cortex. In: Amaducci L, Davison AN, Antuono P (eds) Aging of the brain and dementia. Raven Press, New York, pp 33?38

De Long M (1972) Activity of basal ganglia neurons during movement. Brain Res 4:127?135

Divac J (1975) Magnocellular nuclei of the basal forebrain project to neocortex, brain stem and olfactory bulb. Review of some functional correlates. Brain Res 93:385?398

Fuld PA (1976) Storage retention and retrieval in Korsakoff's syndrome. Neuropsychologia 14:225?236

Fulton JF, Ingraham FD (1929) Emotional disturbances following experimental lesions of the base of the brain (prechiasmal). J Physiol (Lond) 67:27?28

Gorry JR (1963) Studies on the comparative anatomy of the ganglion basale of Meynert. Acta Anat 55:51?104

Hassler R (1938) Zur Pathologie der Paralysis agitans und des postenzephalitischen Parkinsonismus. J Psychol Neurol 48:387?476

Hassler R (1965) Extrapyramidal control of the speed of behavior and its change by primary age prcesses. In: Welford AT, Birrin JT (eds) Behavior, aging, and the nervous system. Thomas, Springfield, IL, pp 284?306

Johnston MV, McKinney N, Coyle JT (1979) Evidence for a cholinergic projection to neocortex from neurons in basal forebrain. Proc Natl Acad Sci USA 76:5392?5396

Jones EG, Burton H, Saper CB, Swanson LW (1976) Midbrain, diencephalic and cortical relationship of the nucleus basalis of Meynert and associated structures in primates. J Comp Neurol 167:385?397

Kimura H, McGeer PL, Peng F, McGeer EG (1980) Choline acetyltransferase-containing neurons in rodent brain demonstrated by immunohistochemistry. Science 208:1057?1059

Kimura H, McGeer PL, Peng F, McGeer EG (1981) The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat. J Comp Neurol 200:151?201

Kitt CA, Price DL, De Long MR, Struble RG, Mitchell SJ, Hedreen JC (1982) The nucleus basalis of Meynert. Projections to the cortex, amygdala and hippocampus. Abstr Ann Meet Soc Neurosci 8:212

Lehman J, Nagy JI, Atmadja S, Fibiger HC (1980) The nucleus basalis magnocellularis: the origin of a cholinergic projection to the neocortex of the rat. Neuroscience 5:1161?1174

Lewy, FH (1923) Die Lehre vom Tonus und der Bewegung. Springer, Berlin

Linseman MA (1974) Inhibitory unit activity of the ventral forebrain during both appetitive and aversive Pavlovian conditioning. Brain Res 80:146?151

Lo Conte G, Casamenti F, Bigl V, Milaneschi E, Pepeu G (1982) Effect of magnocellular forebrain nuclei lesions on acetylcholin output from the cerebral cortex electrocorticogram and behaviour. Arch Ital Biol 120:176?188

Marchbanks RM (1982) Biochemistry of Alzheimer's disease. J Neurochem 39:9?15

McGeer PL, McGeer EG (1976) Enzymes associated with the metabolism of catecholamines, ACh and GABA in human cortex and patients with Parkinson's disease and Huntington's chorea. J Neurochem 26:65?76

McGinty DJ, Sterman MB (1968) Sleep suppression after basal forebrain lesions in the cat. Science 160:1253?1255

Mesulam M, van Hoesen GW (1976) Acetylcholinesterase-rich projections from the basal forebrain of the rhesus monkey to neocortex. Brain Res 109:152?157

Meudell P, Butters N, Montgomery K (1978) Role of rehearsal in the short-term memory performance of patients with Korsakoff's and Huntington's disease. Neuropsychologia 16:507?510

Meyer U, Wenk H, Bigl V (1979) Cholinergic connections in the CNS of rats determined by lesions technique and quantitative histochemistry. In: Matthies H, Krug M, Popov N (eds) Biological aspects of learning, memory formation and ontogeny of the CNS. Proceedings of the Fifth International Neurobiological Symposium, Magdeburg, June 6?9, 1977. Akademie-Verlag, Berlin

Meynert T (1872) Vom Gehirn der Säugetiere. In: Stricker's Handbuch der Lehre von den Geweben des Menschen, Bd. 2. Engelmann, Leipzig

Nakano I, Hirano A (1982) Loss of large neurons of the medial septal nucleus in an autopsy case of Alzheimer's disease. J Neuropathol Exp Neurol 41:341

Nakano I, Hirano A (1982) Neuron loss in the nucleus basalis of Meynert in paralysis agitans and parkinsonism-dementia complex of Guam. Ann Neurol 12:96

Nakano I, Hirano A (1983) Neuron loss in the Nucleus basalis of Meynert in parkinsonism-dementia complex of Guam. Ann Neurol 13:87?91

Obrist WD, Busse EW, Eisdorfer C, Kleemeier RW (1962) Relation of the electroencephalogram to intellectual function in senescence. J Gerontol 17:197?206

Richter JA, Perry EK, Tomlinson BE (1980) Acetylcholine and choline levels in post-mortem human brain tissue: preliminary observations in Alzheimer's disease. Life Sci 26:1683?1689

Robinson BW, Mishkin M (1968) Alimentary responses to forebrain stimulation in monkey. Exp Brain Res 4:330?366

Rolls ET, Sanqhera MK, Roper-Hall A (1979) The latency of activation of neurons in the lateral hypothalamus and substantia innominata during feeding in the monkey. Brain Res 164:121?135

Rossor MN, Svendsen C, Hunt SP, Mountjoy CQ, Roth M, Iversen LL (1982) The substantia innominata in Alzheimer's disease: A histochemical and biochemical study of cholinergic marker enzymes. Neurosci Lett 28:217?222

Ruberg M, Ploska A, Javoy-Agid F, Agid Y (1982) Muscarinic binding and choline acetyltransferase activity in parkinsonian subjects with reference to dementia. Brain Res 232:129?139

Siegel J, Wang RY (1974) Electroencephalographic, behavioral, and single-unit effects produced by stimulation of forebrain inhibitory structures in cats. Exp Neurol 42:28?50

Slaby AE, Wyatt RJ (1974) Dementia in the presenium. Thomas, Springfield, IL

Smith CM, Swash M (1978) Possible biochemical basis of memory disorder in Alzheimer's disease. Ann Neurol 3:471?473

Soininen H, Partanen JV, Puranen M, Riekkinen PJ (1982) EEG and computed tomography in the investigation of patients with senile dementia. J Neurol Neurosurg Psychiatry 45:711?714

Spokes GS (1982) Huntington's chorea. In: Giuffrida Stella AM, Gombos G, Benzi G, Bachelard HS (eds) Basic and clinical aspects of molecular neurobiology. Proc 4th Meet Eur Soc Neurochem. Catania, pp 65?75

Terry RD (1978) Senile dementia. Fed Proc 37:2837?2840

Terry RD, Davies P (1980) Dementia of the Alzheimer type. Ann Rev Neurosci 3:77?95

Terry RD, Fitzgerald C, Peck A, Millner J, Farmer P (1977) Cortical cell counts in senile dementia. J Neuropathol Exp Neurol 36:633

Tomlinson BF, Blessed G, Roth M (1970) Observations on the brains of demented old people. J Neurol Sci 11:205?242

Uhl GR, McKinney M, Hedreen JC, White III CL, Coyle JT, Whitehouse PJ, Price DL (1982) Dementia pugilistica: loss of basal forebrain cholinergic neurons and cortical cholinergic markers. Ann Neurol 12:99

Wang HS (1977) Dementia of old age. In: Smith WL, Kinsbourne M (eds) Aging and dementia. Spectrum, New York, pp 1?24

Wenk H, Bigl V, Meyer U (1980) Cholinergic projections from magnocellular nuclei of the basal forebrain to cortical areas in rats. Brain Res Rev 2:295?316

Wenk H, Bigl V, Meyer U, Biesold D (1981) Cholinergic pathways to the cerebral cortex in rats. In: Pepeu G, Ladinsky H (eds) Cholinergic mechanisms. Phylogenetic aspects, central and peripheral synapses, and clinical significance. Plenum Press, New York London, pp 673?683

Whitehouse PJ, Price DL, Clark AW, Coyle JT, De Long MR (1981) Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol 10:122?126

Whitehouse PJ, Price DL, Sruble RG, Clark AW, Coyle JT, De Long MR (1982) Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215:1237?1239

Yates CM, Simpson J, Maloney AFJ, Gordon A, Reid AH (1980) Alzheimer-like cholinergic deficiency in Down's syndrome. Lancet II:979