Loss of dopaminergic neurons and resulting behavioural deficits in mouse model of Angelman syndrome
Tài liệu tham khảo
Albrecht, 1997, Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons, Nat. Genet., 17, 75, 10.1038/ng0997-75
Brown, 2005, Dopamine depletion alters phosphorylation of striatal proteins in a model of Parkinsonism, Eur. J. Neurosci., 22, 247, 10.1111/j.1460-9568.2005.04190.x
Chandran, 2008, Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function, Neurobiol. Dis., 29, 505, 10.1016/j.nbd.2007.11.011
Clayton-Smith, 2003, Angelman syndrome: a review of the clinical and genetic aspects, J. Med. Genet., 40, 87, 10.1136/jmg.40.2.87
Cummings, 1999, Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice, Neuron, 24, 879, 10.1016/S0896-6273(00)81035-1
Dindot, 2008, The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology, Hum. Mol. Genet., 17, 111, 10.1093/hmg/ddm288
Drucker-Colin, 1991, A new motor test sensitive to aging and dopaminergic function, J. Neurosci. Meth., 39, 153, 10.1016/0165-0270(91)90081-A
Fang, 1999, The spectrum of mutations in UBE3A causing Angelman syndrome, Hum. Mol. Genet., 8, 129, 10.1093/hmg/8.1.129
Fleming, 2004, Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein, J. Neurosci., 24, 9434, 10.1523/JNEUROSCI.3080-04.2004
Goldberg, 2003, Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons, J. Biol. Chem., 278, 43628, 10.1074/jbc.M308947200
Gustin, 2010, Tissue-specific variation of Ube3a protein expression in rodents and in a mouse model of Angelman syndrome, Neurobiol. Dis., 39, 283, 10.1016/j.nbd.2010.04.012
Harbord, 2001, Levodopa responsive Parkinsonism in adults with Angelman syndrome, J. Clin. Neurosci., 8, 421, 10.1054/jocn.2000.0753
Heck, 2008, Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors, Hum. Mol. Genet., 17, 2181, 10.1093/hmg/ddn117
Jiang, 1998, Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation, Neuron, 21, 799, 10.1016/S0896-6273(00)80596-6
Karunakaran, 2007, Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid, FASEB J., 21, 2226, 10.1096/fj.06-7580com
Kim, 2005, Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrindine (MPTP) and oxidative stress, Proc. Natl Acad. Sci. USA, 102, 5215, 10.1073/pnas.0501282102
Kishino, 1997, UBE3A/E6-AP mutations cause Angelman syndrome, Nat. Genet., 15, 70, 10.1038/ng0197-70
Matsuura, 1997, Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion, J. Neurosci. Methods., 73, 45, 10.1016/S0165-0270(96)02211-X
McBride, 2006, Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease, Proc. Natl Acad. Sci. USA, 103, 9345, 10.1073/pnas.0508875103
Meredith, 2006, Behavioral models of Parkinson's disease in rodents: a new look at an old problem, Mov. Disord., 21, 1595, 10.1002/mds.21010
Mishra, 2008, E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity, J. Biol. Chem., 283, 7648, 10.1074/jbc.M706620200
Mishra, 2009, The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of HSP70 bound misfolded proteins, J. Biol. Chem., 284, 10537, 10.1074/jbc.M806804200
Mishra, 2008, Regulation of turnover of tumor suppressor p53 and cell growth by E6-AP, a ubiquitin protein ligase mutated in Angelman mental retardation syndrome, Cell. Mol. Life Sci., 65, 656, 10.1007/s00018-007-7476-1
Mulherkar, 2009, The ubiquitin ligase E6-AP promotes degradation of alpha-synuclein, J. Neurochem., 110, 1955, 10.1111/j.1471-4159.2009.06293.x
Picconi, 2004, Abnormal Ca2+–calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental Parkinsonism, J. Neurosci., 24, 5283, 10.1523/JNEUROSCI.1224-04.2004
Quinn, 2007, A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: pharmacological validation with R-(−)-deprenyl, J. Neurosci. Meth., 164, 43, 10.1016/j.jneumeth.2007.03.021
Rougeulle, 1997, The Angelman syndrome candidate gene, UBE3A/E6-AP, is imprinted in brain, Nat. Genet., 17, 14, 10.1038/ng0997-14
Scheffner, 1993, The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53, Cell, 75, 495, 10.1016/0092-8674(93)90384-3
Tanaka, 2004, Trehalose alleviates polyglutamine-mediated pathology in a model of Huntington disease, Nat. Med., 10, 148, 10.1038/nm985
Wang, 2005, Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis, EMBO J., 24, 4324, 10.1038/sj.emboj.7600895
Weeber, 2003, Derangements of hippocampal calcium/calmodulin-dependent protein kinase II in a mouse model for Angelman mental retardation syndrome, J. Neurosci., 23, 2634, 10.1523/JNEUROSCI.23-07-02634.2003
Yashiro, 2009, Ube3a is required for experience-dependent maturation of the neocortex, Nat. Neurosci., 12, 777, 10.1038/nn.2327