Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment

Abercrombie, 1979, Contact inhibition and malignancy, Nature, 281, 259, 10.1038/281259a0 Astin, 2010, Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells, Nat. Cell Biol., 12, 1194, 10.1038/ncb2122 Bozkurt, 2021, TRAIL signaling promotes entosis in colorectal cancer, J. Cell Biol., 220, e202010030, 10.1083/jcb.202010030 Brown, 2012, Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’, Trends Biochem. Sci., 37, 325, 10.1016/j.tibs.2012.05.002 Buchheit, 2014, Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression, Nat. Rev. Cancer, 14, 632, 10.1038/nrc3789 Dukes, 2011, The MDCK variety pack: choosing the right strain, BMC Cell Biol., 12, 43, 10.1186/1471-2121-12-43 Durgan, 2018, Cancer cell cannibalism: multiple triggers emerge for entosis, Biochim. Biophys. Acta Mol. Cell Res., 1865, 831, 10.1016/j.bbamcr.2018.03.004 Fais, 2018, Cell-in-cell phenomena in cancer, Nat. Rev. Cancer, 18, 758, 10.1038/s41568-018-0073-9 Finicle, 2018, Nutrient scavenging in cancer, Nat. Rev. Cancer, 18, 619, 10.1038/s41568-018-0048-x Florey, 2011, Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes, Nat. Cell Biol., 13, 1335, 10.1038/ncb2363 Frisch, 1994, Disruption of epithelial cell-matrix interactions induces apoptosis, J. Cell Biol., 124, 619, 10.1083/jcb.124.4.619 Garanina, 2017, Consecutive entosis stages in human substrate-dependent cultured cells, Sci. Rep., 7, 12555, 10.1038/s41598-017-12867-6 Hamann, 2017, Entosis is induced by glucose starvation, Cell Rep., 20, 201, 10.1016/j.celrep.2017.06.037 Herzlinger, 1982, The MDCK epithelial cell line expresses a cell surface antigen of the kidney distal tubule, J. Cell Biol., 93, 269, 10.1083/jcb.93.2.269 Ishikawa, 2015, Loss of anchorage primarily induces non-apoptotic cell death in a human mammary epithelial cell line under atypical focal adhesion kinase signaling, Cell Death Dis., 6, e1619, 10.1038/cddis.2014.583 Krajcovic, 2011, A non-genetic route to aneuploidy in human cancers, Nat. Cell Biol., 13, 324, 10.1038/ncb2174 Krishna, 2016, Mechanisms and consequences of entosis, Cell. Mol. Life Sci., 73, 2379, 10.1007/s00018-016-2207-0 Kummer, 2022, A JAM-A-tetraspanin-alphavbeta5 integrin complex regulates contact inhibition of locomotion, J. Cell Biol., 221, e202105147, 10.1083/jcb.202105147 Lee, 2019, Entosis controls a developmental cell clearance in C. elegans, Cell Rep., 26, 3212, 10.1016/j.celrep.2019.02.073 Lugini, 2003, Potent phagocytic activity discriminates metastatic and primary human malignant melanomas: a key role of ezrin, Lab. Invest., 83, 1555, 10.1097/01.LAB.0000098425.03006.42 Mackay, 2018, Genomic instability in mutant p53 cancer cells upon entotic engulfment, Nat. Commun., 9, 3070, 10.1038/s41467-018-05368-1 Mendoza, 2013, Phosphoregulation of the WAVE regulatory complex and signal integration, Semin. Cell Dev. Biol., 24, 272, 10.1016/j.semcdb.2013.01.007 Mendoza, 2011, ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex, Mol. Cell, 41, 661, 10.1016/j.molcel.2011.02.031 Merino, 2016, Survival of the fittest: essential roles of cell competition in development, aging, and cancer, Trends Cell Biol., 26, 776, 10.1016/j.tcb.2016.05.009 Naik, 2014, Junctional adhesion molecule-A suppresses platelet integrin alphaIIbbeta3 signaling by recruiting Csk to the integrin-c-Src complex, Blood, 123, 1393, 10.1182/blood-2013-04-496232 Overholtzer, 2007, A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion, Cell, 131, 966, 10.1016/j.cell.2007.10.040 Paddock, 1986, Analysing collisions between fibroblasts and fibrosarcoma cells: fibrosarcoma cells show an active invasionary response, J. Cell Sci., 81, 163, 10.1242/jcs.81.1.163 Scarpa, 2013, A novel method to study contact inhibition of locomotion using micropatterned substrates, Biol. Open, 2, 901, 10.1242/bio.20135504 Stramer, 2016, Mechanisms and in vivo functions of contact inhibition of locomotion, Nat. Rev. Mol. Cell Biol., 18, 43, 10.1038/nrm.2016.118 Sun, 2014, Induction of entosis by epithelial cadherin expression, Cell Res., 24, 1288, 10.1038/cr.2014.137 Sun, 2014, Competition between human cells by entosis, Cell Res., 24, 1299, 10.1038/cr.2014.138 Sun, 2013, Methods for the study of entosis, Methods Mol. Biol., 1004, 59, 10.1007/978-1-62703-383-1_5 Tholmann, 2022, JAM-A interacts with alpha3beta1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells, Cell. Mol. Life Sci., 79, 88, 10.1007/s00018-022-04140-5 Tuncay, 2015, JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis, Nat. Commun., 6, 8128, 10.1038/ncomms9128 Wang, 2015, Impaired formation of homotypic cell-in-cell structures in human tumor cells lacking alpha-catenin expression, Sci. Rep., 5, 12223, 10.1038/srep12223 Wang, 2016, Cell-in-cell death is not restricted by caspase-3 deficiency in MCF-7 cells, J. Breast Cancer, 19, 231, 10.4048/jbc.2016.19.3.231 Winkler, 2020, Concepts of extracellular matrix remodelling in tumour progression and metastasis, Nat. Commun., 11, 5120, 10.1038/s41467-020-18794-x Yeatman, 2004, A renaissance for SRC, Nat. Rev. Cancer, 4, 470, 10.1038/nrc1366