Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cell Reports Medicine - Tập 3 - Trang 100833 - 2022
Cedric Bosteels1,2,3, Karel F.A. Van Damme1,2,3, Elisabeth De Leeuw1,2,3, Jozefien Declercq1,2,3, Bastiaan Maes1,2,3, Victor Bosteels2,3,4, Levi Hoste2,5, Leslie Naesens2,5, Nincy Debeuf1,2,3, Julie Deckers1,2,3, Basiel Cole2, Marion Pardons2, Daniela Weiskopf6, Alessandro Sette6,7, Yannick Vande Weygaerde3, Thomas Malfait3, Stefaan J. Vandecasteele8, Ingel K. Demedts9, Hans Slabbynck10, Sabine Allard11
1Laboratory of Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent University, 9000 Ghent, Belgium
2Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium
3Department of Respiratory Medicine, Ghent University Hospital, 9000 Ghent, Belgium
4Laboratory of ER Stress and Inflammation, VIB-UGent Center for Inflammation Research, Ghent University, 9000 Ghent, Belgium
5Primary Immunodeficiency Research Lab, Faculty of Medicine and Health Sciences, Ghent University, Ghent 9000, Belgium
6Center for Autoimmunity and Inflammation and Center for Infectious Diseases and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA 92037, USA
7Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA
8Department of Infectious Diseases, AZ Sint-Jan Brugge-Oostende, 8000 Brugge, Belgium
9Department of Pulmonary Medicine, AZ Delta General Hospital, 8800 Roeselare, Belgium
10Department of Pulmonary Medicine, ZNA General Hospital, 2000 Antwerp, Belgium
11Department of Internal Medicine, Universitair Ziekenhuis Brussel, 1000 Brussels, Belgium

Tài liệu tham khảo

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