Longxuetongluo Capsule protects against cerebral ischemia/reperfusion injury through endoplasmic reticulum stress and MAPK-mediated mechanisms

Journal of Advanced Research - Tập 33 - Trang 215-225 - 2021
Bo Pan1, Jing Sun1, Ziyu Liu1, Lingxiao Wang1, Hui-Xia Huo1, Yunfang Zhao1, Pengfei Tu1, Wei Xiao2, Jiao Zheng1, Jun Li1
1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China
2Jiangsu Kanion Parmaceutical Co. Ltd., Lianyungang, Jiangsu 222001, China

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Tài liệu tham khảo

Marciniec, 2019, Non-traumatic cervical artery dissection and ischemic stroke: a narrative review of recent research, Clin Neurol Neurosur, 187, 10.1016/j.clineuro.2019.105561

Perez-de-Puig, 2015, Neutrophil recruitment to the brain in mouse and human ischemic stroke, ACTA Neuropathol, 129, 239, 10.1007/s00401-014-1381-0

Wei, 2017, Downregulation of Trb3 protects neurons against apoptosis induced by global cerebral ischemia and reperfusion Injury in rats, Neuroscience, 360, 118, 10.1016/j.neuroscience.2017.07.062

Shu, 2018, Protective effects of Progranulin against focal cerebral ischemia-reperfusion injury in rats by suppressing endoplasmic reticulum stress and NF-kappa B activation in reactive astrocytes, J Cell Biochem, 119, 6584, 10.1002/jcb.26790

Pluquet, 2015, The unfolded protein response and cellular senescence. A review in the theme: cellular mechanisms of endoplasmic reticulum stress signaling in health and disease, Am J Physiol-Cell Ph, 308, 415, 10.1152/ajpcell.00334.2014

Hashimoto, 2018, Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease, Open Biol, 8, 10.1098/rsob.180024

Wan, 2019, WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death, Autophagy, 23, 1

Hollville, 2019, Apoptotic cell death regulation in neurons, FEBS J, 286, 3276, 10.1111/febs.14970

Garrido, 2006, Mechanisms of cytochrome c release from mitochondria, Cell Death Differ, 13, 1423, 10.1038/sj.cdd.4401950

Jin, 2017, Neuroprotective activity of cerebrosides from typhonium giganteum by regulating caspase-3 and Bax/Bcl-2 signaling pathways in PC12 cells, J Nat Prod, 80, 1734, 10.1021/acs.jnatprod.6b00954

Radak, 2017, Apoptosis and acute brain ischemia in ischemic stroke, Curr Vasc Pharmacol, 15, 115, 10.2174/1570161115666161104095522

Broughton, 2009, Apoptotic mechanisms after cerebral ischemia, Stroke, 40, 331, 10.1161/STROKEAHA.108.531632

Chen, 2003, A patch test study of 27 crude drugs commonly used in Chinese topical medicaments, Contact Dermatitis, 49, 8, 10.1111/j.0105-1873.2003.00125.x

Li, 2012, Dragon's Blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats, J Pharmacol Sci, 118, 43, 10.1254/jphs.11160FP

Liu, 2013, Evaluation of the wound healing potential of resina Draconis (Dracaena cochinchinensis) in animal models, Evid-Based Compl Alt, 2013

Zhu, 2007, Anti-Helicobacter pylori and thrombin inhibitory components from Chinese Dragon's blood, Dracaena cochinchinensis, J Nat Prod, 70, 1570, 10.1021/np070260v

Zheng, 2016, Longxuetongluo capsule inhibits atherosclerosis progression in high-fat diet-induced ApoE(-/-) mice by improving endothelial dysfunction, Atherosclerosis, 255, 156, 10.1016/j.atherosclerosis.2016.08.022

Su, 2014, Dihydrochalcones and homoisoflavanes from the red resin of Dracaena cochinchinensis (Chinese dragon's blood), Fitoterapia, 99, 64, 10.1016/j.fitote.2014.09.006

Sun, 2017, Characterization and quantitative analysis of phenolic derivatives in Longxuetongluo Capsule by HPLC-DAD-IT-TOF-MS, J Pharm Biomed Anal, 145, 462, 10.1016/j.jpba.2017.07.012

Sun, 2018, Method development and application for multi-component quantification in rats after oral administration of Longxuetongluo Capsule by UHPLC-MS/MS, J Pharm Biomed Anal, 156, 252, 10.1016/j.jpba.2018.04.030

Zheng, 2016, Longxuetongluo Capsule improves erythrocyte function against lipid peroxidation and abnormal hemorheological parameters in high fat diet-Induced ApoE-/- mice, Oxid Med Cell Longev, 2016, 2603219, 10.1155/2016/2603219

Gerlier, 1986, Use of MTT colorimetric assay to measure cell activation, J Immunol Methods, 94, 57, 10.1016/0022-1759(86)90215-2

Longa, 1989, Reversible middle cerebral artery occlusion without craniectomy in rats, Stroke, 20, 84, 10.1161/01.STR.20.1.84

Koike, 2016, Advanced glycation end-products induce apoptosis of vascular smooth muscle cells: a mechanism for vascular calcification, Int J Mol Sci, 17, 1567, 10.3390/ijms17091567

Li, 2005, The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers, Brain Res, 1048, 59, 10.1016/j.brainres.2005.04.058

Kasibhatla, 2006, Acridine orange/ethidium bromide (AO/EB) staining to detect apoptosis, CSH Protoc, 2006, 4493

Wang, 2016, Notoginsenoside R1 protects against neonatal cerebral hypoxic-ischemic injury through estrogen receptor-dependent activation of endoplasmic reticulum stress pathways, J Pharmacol Exp Ther, 357, 591, 10.1124/jpet.115.230359

Cao, 2002, Cloning and characterization of rat caspase-9: implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia, J Cereb Blood Flow Metab, 22, 534, 10.1097/00004647-200205000-00005

Zhang, 2008, From endoplasmic-reticulum stress to the inflammatory response, Nature, 454, 455, 10.1038/nature07203

Tabas, 2011, Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress, Nat Cell Biol, 13, 184, 10.1038/ncb0311-184

Darling, 2014, The role of MAPK signalling pathways in the response to endoplasmic reticulum stress, Biochim Biophys Acta, 1843, 2150, 10.1016/j.bbamcr.2014.01.009

Ron, 2007, Signal integration in the endoplasmic reticulum unfolded protein response, Nat Rev Mol Cell Biol, 8, 519, 10.1038/nrm2199

Davis, 2000, Signal transduction by the JNK group of MAP kinases, Cell, 103, 239, 10.1016/S0092-8674(00)00116-1

Wei, 2013, Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models, Kidney Int, 84, 138, 10.1038/ki.2013.68

Zou, 2015, Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines, ACS Chem Neurosci, 6, 464, 10.1021/cn500297v

Tanaka, 2019, The 5-reductase inhibitor finasteride exerts neuroprotection against ischemic brain injury in aged male rats, Transl Stroke Res, 10, 67, 10.1007/s12975-018-0624-0

Eltzschig, 2011, Ischemia and reperfusion-from mechanism to translation, Nat Med, 17, 1391, 10.1038/nm.2507

Harding, 2000, Perk is essential for translational regulation and cell survival during the unfolded protein response, Mol Cell, 5, 897, 10.1016/S1097-2765(00)80330-5

Xin, 2013, Dragon's blood dropping pills have protective effects on focal cerebral ischemia rats model, Phytomedicine, 21, 68, 10.1016/j.phymed.2013.08.007

Hong, 2020, Longxuetongluo capsule alleviates lipopolysaccharide-induced neuroinflammation by regulating multiple signaling pathways in BV2 microglia cells, J Chin Med Assoc, 83, 255, 10.1097/JCMA.0000000000000258

Bertolotti, 2000, Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response, Nat Cell Biol, 2, 326, 10.1038/35014014

Malhotra, 2007, The endoplasmic reticulum and the unfolded protein response, Semin Cell Dev Biol, 18, 716, 10.1016/j.semcdb.2007.09.003

Puthalakath, 2007, ER stress triggers apoptosis by activating BH3-only protein Bim, Cell, 129, 1337, 10.1016/j.cell.2007.04.027

Kim, 2006, JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells, J Biol Chem, 281, 21256, 10.1074/jbc.M510644200

Yu, 2016, Melatonin reduces PERK-eIF2alpha-ATF4-mediated endoplasmic reticulum stress during myocardial ischemia-reperfusion injury: role of RISK and SAFE pathways interaction, Apoptosis, 21, 809, 10.1007/s10495-016-1246-1

Wei, 2016, Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure, Am J Physiol Heart Circ Physiol, 311, 871, 10.1152/ajpheart.00362.2016