Long-term results of a randomized, controlled, double-blind study of low-level laser therapy before exercises in knee osteoarthritis: laser and exercises in knee osteoarthritis

Clinical Rehabilitation - Tập 32 Số 2 - Trang 173-178 - 2018
Patrícia Pereira Alfredo1, Jan Magnus Bjordal2, Washington Steagall3, Rodrigo Álvaro Brandão Lopes‐Martins4,5, Martin Bjørn Stausholm2, Raquel Aparecida Casarotto1, Amélia Pasqual Marques1, Jón Joensen2
1Department of Physical Therapy, Speech Therapy and Occupational Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil
2Physiotherapy Research Group, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
3Department of Dentistry, School of Odontology, University of São Paulo, São Paulo, Brazil
4Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
5Technological Research Center - NPT, University of Mogi das Cruzes-UMC, Brazil

Tóm tắt

Objectives: To assess the long-term effects of low-level laser therapy (LLLT), in combination with strengthening exercises in patients with osteoarthritis of the knee. Design: Follow-up results at three and six months in a previously published randomized, double-blind, placebo-controlled trial. Setting: Specialist Rehabilitation Services. Subjects: Forty participants of both genders, aged 50–75 years with knee osteoarthritis grade 2–4 on Kellgren–Lawrence scale. Intervention: The LLLT group received 10 LLLT treatments with invisible infrared laser (904 nm, 3 Joules/point) over three weeks followed by an eight-week supervised strengthening exercise program. The placebo LLLT group received identical treatment, but the infrared laser output was disabled. Main measures: Pain on a visual analogue scale, paracetamol consumption, and osteoarthritis severity measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Lequesne Index. Results: The new data obtained during the follow-up period showed that all outcomes remained stable and there were no significant differences between the groups at three and six months. However, daily consumption of rescue analgesics (paracetamol) was significantly lower in the LLLT group throughout the follow-up period, ending at a group difference of 0.45 vs. 3.40 units ( P < 0.001) at six months follow-up. We conclude that within the limitations of this small study, the previously reported improvement after LLLT plus exercise was maintained for a period of six months. Conclusion: We find that the immediate post-intervention improvements from LLLT plus strengthening exercises were maintained for six months.

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Clinical Rehabilitation

Tập 32 Số 2

173-178

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