Long-term administration of Aspalathus linearis infusion affects spatial memory of adult Sprague-Dawley male rats as well as increases their striatal dopamine content

Akinrinmade, 2017, Long-term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats, Acta Neurobiol. Exp., 77, 94, 10.21307/ane-2017-040 Arias-Carrión, 2010, Dopaminergic reward system: a short integrative review, Int. Arch. Med., 3, 24, 10.1186/1755-7682-3-24 Baldan Ramsey, 2010, Cued and spatial learning in the water maze: equivalent learning in male and female mice, Neurosci. Lett., 483, 148, 10.1016/j.neulet.2010.07.082 Bezu, 2017, Spatial working memory in male rats: pre-experience and task dependent roles of dopamine D1- and D2-like receptors, Front. Behav. Neurosci., 11, 196, 10.3389/fnbeh.2017.00196 Cools, 2011, Inverted-U-shaped dopamine actions on human working memory and cognitive control, Biol. Psychiatry, 69, e113, 10.1016/j.biopsych.2011.03.028 Dludla, 2014, The cardioprotective effect of an aqueous extract of „fermented” rooibos (Aspalathus linearis) on cultured cardiomyocytes derived from diabetic rats, Phytomedicine, 21, 595, 10.1016/j.phymed.2013.10.029 Hong, 2014, Anti-oxidative effects of Rooibos tea (Aspalathus linearis) on immobilization-induced oxidative stress in rat brain, PLoS One, 21 Inanami, 1995, The suppression of age-related accumulation of lipid peroxides in rat brain by administration of Rooibos tea (Aspalathus linearis), Neurosci. Lett., 196, 85, 10.1016/0304-3940(95)11853-O Johnson, 2016, Aspalathin, a dihydrochalcone C-glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis, Mol. Nutr. Food Res., 60, 922, 10.1002/mnfr.201500656 Johnson, 2017, Aspalathin reverts doxorubicin-induced cardiotoxicity through ncreased autophagy and decreased expression of p53/mTOR/p62 Signaling, Molecules, 22, E1589, 10.3390/molecules22101589 Johnson, 2018, Aspalathin from rooibos (aspalathus linearis): a bioactive C-glucosyl dihydrochalcone with potential to target the metabolic syndrome, Planta Med., 84, 568, 10.1055/s-0044-100622 Joubert, 2011, Rooibos (Aspalathus linearis) beyond the farm gate: from herbal tea to potential phytopharmaceutical, South Afr. J. Bot., 77, 869, 10.1016/j.sajb.2011.07.004 Joubert, 2013, Occurrence and sensory perception of Z-2-(β-d-glucopyranosyloxy)-3-phenylpropenoic acid in rooibos (Aspalathus linearis), Food Chem., 136, 1078, 10.1016/j.foodchem.2012.09.014 Joubert, 2014, Antioxidants of rooibos beverages: role of plant composition and processing, 131 Kawano, 2009, Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice, Phytomedicine, 16, 437, 10.1016/j.phymed.2008.11.009 Krafczyk, 2008, Characterization of phenolic compounds in rooibos tea, J. Agric. Food Chem., 56, 3368, 10.1021/jf703701n Ku, 2015, Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo, Inflammation, 38, 445, 10.1007/s10753-014-0049-1 Le Moal, 1991, Mesocorticolimbic dopaminergic network – functional and regulatory roles, Physiol. Rev., 71, 155, 10.1152/physrev.1991.71.1.155 Marnewick, 2003, Modulation of hepatic drug metabolizing enzymes and oxidative status by rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia), green and black (Camellia sinensis) teas in rats, J. Agric. Food Chem., 51, 8113, 10.1021/jf0344643 Marnewick, 2011, Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease, J. Ethnopharmacol., 133, 46, 10.1016/j.jep.2010.08.061 Mazibuko, 2013, Amelioration of palmitate-induced insulin resistance in C₂C₁₂ muscle cells by rooibos (Aspalathus linearis), Phytomedicine, 20, 813, 10.1016/j.phymed.2013.03.018 Morton, 1983, Rooibos tea, aspalathus linearis, a caffeineless, low-tannin beverage, Econ. Bot., 37, 164, 10.1007/BF02858780 Muller, 2018, Potential of rooibos, its major C-glucosyl flavonoids, and Z-2-(b-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome, Crit. Rev. Food Sci. Nutr., 58, 227, 10.1080/10408398.2016.1157568 Muller, 2013, Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid, an α-hydroxy acid from rooibos (Aspalathus linearis) with hypoglycemic activity, Mol. Nutr. Food Res., 57, 2216, 10.1002/mnfr.201300294 Muller, 2018, Potential of rooibos, its major C-glucosyl flavonoids and Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome, Crit. Rev. Food Sci. Nutr., 58, 227, 10.1080/10408398.2016.1157568 Packard, 1994, Amygdala modulation of hippocampal-dependent and caudate nucleus-dependent memory processes, Proc. Natl. Acad. Sci. U.S.A., 91, 8477, 10.1073/pnas.91.18.8477 Packard, 1998, Amygdala modulation of multiple memory systems: hippocampus and caudate-putamen, Neurobiol. Learn. Mem., 69, 163, 10.1006/nlme.1997.3815 Pantsi, 2011, Rooibos (Aspalathus linearis) offers cardiac protection against ischaemia/reperfusion in the isolated perfused rat heart, Phytomedicine, 18, 1220, 10.1016/j.phymed.2011.09.069 Reed, 2010, Effect size of reference memory deficits in the Morris water maze in Tg2576 mice, Behav. Brain Res., 212, 115, 10.1016/j.bbr.2010.03.037 Sasaki, 2018, A beneficial role of rooibos in diabetes mellitus: a systematic review and meta-analysis, Molecules, 23, 839, 10.3390/molecules23040839 Smith, 2018, Aspalathus linearis (Rooibos) - a functional food targeting cardiovascular disease, Food Funct, 9, 5041, 10.1039/C8FO01010B Stalmach, 2009, Bioavailability of C-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas, J. Agric. Food Chem., 57, 7104, 10.1021/jf9011642 Stander, 2017, Analysis of phenolic compounds in rooibos tea (Aspalathus linearis) with a comparison of flavonoid-based compounds in natural populations of plants from different regions, J. Agric. Food Chem., 65, 10270, 10.1021/acs.jafc.7b03942 Van Wyk, 2008, A review of Khoi-San and Cape Dutch medical ethnobotany, J. Ethnopharmacol., 119, 331, 10.1016/j.jep.2008.07.021 Van Wyk, 2008, A broad review of commercially important southern African medicinal plants, J. Ethnopharmacol., 119, 342, 10.1016/j.jep.2008.05.029 Van Wyk, 2011, The potential of South African plants in the development of new medical products, South Afr. J. Bot., 77, 812, 10.1016/j.sajb.2011.08.011 Van Wyk, 2017, The history and ethnobotany of Cape herbal teas, South Afr. J. Bot., 110, 18, 10.1016/j.sajb.2016.11.011 Villaño, 2010, Unfermented and fermented rooibos teas (Aspalathus linearis) increase plasma total antioxidant capacity in healthy humans, Food Chem., 123, 679, 10.1016/j.foodchem.2010.05.032 Vorhees, 2006, Morris water maze: procedures for assessing spatial and related forms of learning and memory, Nat. Protoc., 1, 848, 10.1038/nprot.2006.116 Waisundara, 2015, Free radical scavenging ability of Aspalathus linearis in two in vitro models of diabetes and cancer, J. Tradit. Complement. Med., 5, 174, 10.1016/j.jtcme.2014.11.009 Widy-Tyszkiewicz, 1993, Spatial navigation learning in spontaneously hypertensive, renal hypertensive and normotensive Wistar rats, Behav. Brain Res., 54, 179, 10.1016/0166-4328(93)90077-4 Zahrt, 1997, Supranormal stimulation of D1 dopamine receptors in the rodent prefrontal cortex impairs spatial working memory performance, J. Neurosci., 17, 8528, 10.1523/JNEUROSCI.17-21-08528.1997