Long-Term Expression Driven by Herpes Simplex Virus Type-1 Amplicons May Fail Due to Eventual Degradation or Extrusion of Introduced Transgenes
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Andrulis, 1998, Perinuclear localization of chromatin facilitates transcriptional silencing, Nature, 394, 592, 10.1038/29100
Dash, 1996, A herpes simplex virus vector overexpressing the glucose transporter gene protects the rat dentate gyrus from an antimetabolite toxin, Exp. Neurol., 137, 43, 10.1006/exnr.1996.0005
Deluca, 1985, Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4, J. Virol., 56, 558, 10.1128/JVI.56.2.558-570.1985
During, 1994, Long term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase, Science, 266, 1399, 10.1126/science.266.5189.1399
Fink, 1997, Defective herpes simplex virus vectors expressing the rat brain stress-inducible heat shock protein 72 protect cultured neurons from severe heat shock, J. Neurochem., 68, 961, 10.1046/j.1471-4159.1997.68030961.x
Geller, 1997, Helper virus-free herpes simplex virus-1 plasmid vectors for gene therapy of Parkinson's disease and other neurological disorders, Exp. Neurol., 144, 98, 10.1006/exnr.1996.6394
Gussoni, 1996, A method to co-detect introduced genes and their products in gene therapy protocols, Nature Biotechnol., 14, 1012, 10.1038/nbt0896-1012
Ho, 1994, Amplicon-based herpes simplex virus vectors, 191, 10.1016/S0091-679X(08)60604-4
Ho, 1995, Use of herpes simplex virus vectors for protection from necrotic neuron death, 133
Ho, 1996, Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system, Mol. Brain Res., 41, 200, 10.1016/0169-328X(96)00097-6
Kaplitt, 1997, Defective viral vectors as agents for gene transfer in the nervous system, J. Neurosci. Methods, 71, 125, 10.1016/S0165-0270(96)00132-X
Kennedy, 1997, Potential use of HSV vectors for gene therapy of neurological disorders, Brain, 120, 1245, 10.1093/brain/120.7.1245
Lamond, 1998, Structure and function in the nucleus, Science, 280, 547, 10.1126/science.280.5363.547
Laroche, 1998, Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres, Curr. Biology, 8, 653, 10.1016/S0960-9822(98)70252-0
Lawrence, 1996, Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurologic insults in vitro and in vivo, J. Neurosci., 16, 486, 10.1523/JNEUROSCI.16-02-00486.1996
Meier, 1998, Gene transfer of calbindin D28K cDNA via herpes simplex virus amplicon vector decreases calcium ion mobilization and enhances neuronal survival following glutamatergic challenge but not following cyanide, J. Neurochem., 70, 1013, 10.1046/j.1471-4159.1998.71031013.x
Misteli, 1998, The cellular organization of gene expression, Curr. Opin. Cell Biol., 10, 323, 10.1016/S0955-0674(98)80007-0
Naldini, 1996, In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector, Science, 272, 263, 10.1126/science.272.5259.263
Paxinos, 1986
Puck, 1996, DNA exposure and condensation in the X and 21 chromosomes, Stem Cells, 14, 548, 10.1002/stem.140548
Shimizu, 1998, Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase, J. Cell Biol., 140, 1307, 10.1083/jcb.140.6.1307
Starr, 1996, Long-term persistence of defective HSV-1 vectors in the rat brain is demonstrated by reactivation of vector gene expression, Gene Ther., 3, 615
Tsai, D. J, K. I. Park, and, E. Y. Snyder, Some of the dynamics and variables influencing retrovirally-transduced foreign gene expression by engrafted neural stem cells. Manuscript in preparation.
Yenari, 1998, Gene therapy with hsp72 is neuroprotective in rat models of stroke and epilepsy, Ann. Neurol., 44, 584, 10.1002/ana.410440403
Yuen, 1996, Therapeutic potential of neurotrophic factors for neurological disorders, Ann. Neurol., 40, 346, 10.1002/ana.410400304