Locomotor Training in Subjects with Sensori‐Motor Deficits: An Overview of the Robotic Gait Orthosis Lokomat

Journal of Healthcare Engineering - Tập 1 Số 2 - Trang 197-216 - 2010
Robert Riener1, Lars Lünenburger2, Irin C. Maier3, Giorgio Colombo2, V Dietz2
1ETH Zürich, Zurich ZH, Switzerland
2Uniklinik Balgrist, Zurich, Switzerland
3University of Zurich, Brain Research Institute, Zurich, Switzerland

Tóm tắt

It is known that improvement in walking function can be achieved in patients suffering a movement disorder after stroke or spinal cord injury by providing intensive locomotor training. Rehabilitation robots allow for a longer and more intensive training than that achieved by conventional therapies. Robot assisted treadmill training also offers the ability to provide objective feedback within one training session and to monitor functional improvements over time. This article provides an overview of the technical features and reports the clinical data available for one of these systems known as "Lokomat". First, background information is given for the neural mechanisms of gait recovery. The basic technical approach of the Lokomat system is then described. Furthermore, new features are introduced including cooperative control strategies, assessment tools and augmented feedback. These features may be capable of further enhancing training intensity and patient participation. Findings from clinical studies are presented covering the feasibility as well as efficacy of Lokomat assisted treadmill training.

Từ khóa


Tài liệu tham khảo

10.1161/01.CIR.97.24.2474

10.1016/S0003-9993(95)80038-7

Waters R. L., 1998, Donal munro lecture: Functional and neurologic recovery following acute sci, J Spinal Cord Med, 21, 195

10.1007/BF02447435

10.1002/ana.410370506

10.1016/S1047-9651(02)00061-X

10.1310/UDXE-MJFF-53V2-EAP0

10.1038/sc.1992.61

10.1089/neu.1999.16.719

Colombo G., 2000, Treadmill training of paraplegic patients using a robotic orthosis, J Rehabil Res Dev, 37, 693

Hesse S., 2000, A mechanized gait trainer for restoration of gait, J Rehabil Res Dev, 37, 701

10.1097/WCO.0b013e3282f36cb6

10.1152/japplphysiol.00942.2003

10.1016/S1474-4422(04)00771-9

10.1093/brain/117.5.1143

10.1093/brain/111.5.1235

10.1016/S0140-6736(94)90751-X

10.1016/j.brainresbull.2008.02.034

Dietz V., 2009, Changes in spinal reflex and locomotor activity after a complete spinal cord injury: A common mechanism?, Brain

Dobkin B. H., 1995, Modulation of locomotor-like emg activity in subjects with complete and incomplete spinal cord injury, J Neurol Rehabil, 9, 183

10.1152/jn.1997.77.2.797

10.1152/jn.1993.70.3.1009

10.1152/physrev.1992.72.1.33

10.1093/brain/awf273

10.1016/j.apmr.2004.08.004

10.1016/S0003-9993(96)90219-1

10.1016/S0003-9993(97)90007-1

10.1016/S0003-9993(98)90213-1

Katoh S., 1994, Neurological recovery after conservative treatment of cervical cord injuries, J Bone Joint Surg Br, 76, 225, 10.1302/0301-620X.76B2.8113281

10.1016/S0003-9993(03)00361-7

Dietz V., 1995, Locomotor training in paraplegic patients, Ann Neurol, 38, 10.1002/ana.410380621

10.1161/01.STR.29.6.1122

10.1177/1545968306295556

Moseley A. M., Treadmill training and body weight support for walking after stroke, Cochrane Database Syst Rev

Dietz V., 2006, Good clinical practice in neurorehabilitation, Lancet Neurol, 5, 377, 10.1016/S1474-4422(06)70420-3

10.1097/NPT.0b013e3180690679

10.1109/TNSRE.2007.903919

10.1109/TNSRE.2008.2008280

10.1109/TNSRE.2007.903922

Ruthenberg B. J., 1997, An experimental device for investigating the force and power requirements of a powered gait orthosis, J Rehabil Res Dev, 34, 203

Lünenburger L., 2006, Gait retraining after neurological disorders, Wiley Encyclopedia for Biomedical Engineering, 10.1002/9780471740360.ebs1393

10.1109/TNSRE.2006.881556

ColomboG.andBucherR..

Bernstein N. A., The co-ordination and regulation of movements

Huang V. S., 2009, Robotic neurorehabilitation: A computational motor learning perspective, J Neuroeng Rehabil, 6, 10.1186/1743-0003-6-5

Lewek M. D., 2009, Allowing intralimb kinematic variability during locomotor training poststroke improves kinematic consistency: A subgroup analysis from a randomized clinical trial, Phys Ther

10.1109/TNSRE.2009.2033061

10.1109/TNSRE.2005.848628

10.1115/1.3140702

LanceJ. W. Spasticity: Disordered motor control. Year Book chapter Pathophysiology of spasticity and clinical experience with Baclofen 1980:184–204.

10.1542/peds.111.1.e89

Ashworth B., 1964, Preliminary trial of carisoprodol in multiple sclerosis, Practitioner, 192, 540

10.1093/ptj/67.2.206

LünenburgerL. ColomboG. RienerR. andDietzV. Clinical assessments performed during robotic rehabilitation by the gait training robot lokomat. 2005:345–348.

10.1682/JRRD.2005.02.0046

BolligerM. LünenburgerL. BircherS. ColomboG. andDietzV. Reliability of measuring isometric peak torque in the driven gait orthosis ”lokomat“.

Basmajian J. V., Muscles alive: Their functions revealed by electromyography

Schmidt R. A., 2000, Motor learning and performance

Lunenburger L., 2007, Biofeedback for robotic gait rehabilitation, J Neuroeng Rehabil, 4, 10.1186/1743-0003-4-1

LunenburgerL. ColomboG. RienerR. andDietzV. Biofeedback in gait training with the robotic orthosis lokomat 7 4888–4891.

Banz R., 2008, Computerized visual feedback: An adjunct to robotic-assisted gait training, Phys Ther, 88, 1135, 10.2522/ptj.20070203

10.1109/TNSRE.2008.2008281

LünenburgerL. WellnerM. BanzR. ColomboG. andRienerR. Combining immersive virtual environments with robot-aided gait training.

10.1177/1352458507082358

Borggraefe I., 2010, Sustainability of motor performance after robotic-assisted treadmill therapy in children: An open, non-randomized baseline-treatment study, Eur J Phys Rehabil Med

10.1002/mds.21802

Borggraefe I., 2010, Robotic-assisted treadmill therapy improves walking and standing performance in children and adolescents with cerebral palsy, Eur J Paediatr Neurol, 10.1016/j.ejpn.2010.01.002

10.1177/1545968308326632

10.1161/STROKEAHA.107.504779

10.1093/ptj/85.1.52

10.1161/01.STR.0000254607.48765.cb

10.1177/1545968308318473

10.1177/1545968307300697

10.1136/adc.2008.145458

10.1111/j.1469-8749.2007.00900.x

10.1016/j.pmrj.2009.03.009

Westlake K. P., 2009, Pilot study of lokomat versus manual-assisted treadmill training for locomotor recovery post-stroke, J Neuroeng Rehabil, 6, 10.1186/1743-0003-6-18

10.1177/1545968305281515

Nooijen C. F., 2009, Gait quality is improved by locomotor training in individuals with sci regardless of training approach, J Neuroeng Rehabil, 6, 10.1186/1743-0003-6-36

MirbagheriM. M. C. TsaoC. PelosinE. andRymerW. Z. Therapeutic effects of robotic-assisted locomotor training on neuromuscular properties.

Sherman M. F., 2009, Locomotor-respiratory synchronization after body weight supported treadmill training in incomplete tetraplegia: A case report, Spinal Cord, 10.1038/sc.2009.50

Hunt K. J., 2007, Control of work rate-driven exercise facilitates cardiopulmonary training and assessment during robot-assisted gait in incomplete spinal cord injury, Biomed Signal Process Control

10.2522/ptj.20050266

Meyer-Heim A., 2009, Improvement of walking abilities after robotic-assisted locomotion training in children with cerebral palsy, Arch Dis Child, 10.1136/adc.2008.145458

10.1016/S0140-6736(98)09477-X

10.1080/10790268.2004.11753734

10.1177/1545968308317973

Kamibayashi K., 2009, Facilitation of corticospinal excitability in the tibialis anterior muscle during robot-assisted passive stepping in humans, Eur J Neurosci, 10.1111/j.1460-9568.2009.06795.x

Querry R. G., 2008, Synchronous stimulation and monitoring of soleus h reflex during robotic body weight-supported ambulation in subjects with spinal cord injury, J Rehabil Res Dev, 45, 175, 10.1682/JRRD.2007.02.0028

10.1093/brain/awh255

MagagninV. CaianiE. G. FusiniL. TurielM. LicariV. BoI. CeruttiS. andPortaA. Assessment of the cardiovascular regulation during robotic assisted locomotion in normal subjects: Autoregressive spectral analysis vs empirical mode decomposition 3844–3847.

10.1016/j.gaitpost.2008.11.013