Locating and targeting moving tumors with radiation beams

Medical Physics - Tập 35 Số 12 - Trang 5684-5694 - 2008
Sonja Dieterich1, Kevin Cleary2, W DˈSouza3, Martin J. Murphy4, Kenneth H. Wong2, Paul Keall5
1Radiation Oncology, Stanford University, Stanford, California 94305 and Radiation Oncology, Georgetown UniversityHospital, Washington, DC 20007
2Imaging Science and Information Systems, Georgetown UniversityHospital, Washington, DC 20007
3Radiation Oncology, University of Maryland, College Park, Maryland 20742
4Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23284
5Radiation Oncology, Stanford University, Stanford, California 94305

Tóm tắt

The current climate of rapid technological evolution is reflected in newer and better methods to modulate and direct radiation beams for cancer therapy. This Vision paper focuses on part of this evolution, locating and targeting moving tumors. The two processes are somewhat independent and in principle different implementations of the locating and targeting processes can be interchanged. Advanced localization and targeting methods have an impact on treatment planning and also present new challenges for quality assurance (QA), that of verifying real‐time delivery. Some methods to locate and target moving tumors with radiation beams are currently FDA approved for clinical use—and this availability and implementation will increase with time. Extensions of current capabilities will be the integration of higher order dimensionality, such as rotation and deformation in addition to translation, into the estimate of the patient pose and real‐time reoptimization and adaption of delivery to the dynamically changing anatomy of cancer patients.

Từ khóa


Tài liệu tham khảo

10.1016/j.radonc.2008.01.012

10.1118/1.2349696

10.1016/S0360-3016(00)80127-3

10.1016/S0360‐3016(00)00809‐9

10.1016/S0360‐3016(01)01641‐8

10.1016/S0360‐3016(00)00748‐3

10.1016/S0140‐6736(99)00700‐X

10.1088/0031‐9155/49/2/005

10.1088/0031‐9155/53/11/006

10.1088/0031‐9155/49/17/019

10.1016/j.radonc.2007.10.034

10.1088/0031‐9155/52/14/017

10.1118/1.2839104

10.1118/1.1915934

Wu J., 2006, 3799

10.1118/1.1634482

10.1016/j.meddos.2007.01.007

10.1016/j.ijrobp.2006.01.050

10.1016/j.ijrobp.2004.11.009

10.1016/j.ijrobp.2006.10.026

10.1088/0031‐9155/51/11/017

Wink N., 2006, Phase versus amplitude sorting of 4D‐CT data, Med. Phys., 7, 77

10.1016/S0360‐3016(99)00056‐5

10.1016/S0360‐3016(99)00154‐6

10.1016/j.radonc.2007.10.038

10.1053/j.semradonc.2003.10.005

10.1118/1.1774132

C.Ozhasoglu M. J.Murphy G.Glosser M.Bodduluri A.Schweikard K.Forster D. P.Martin andJ. R.Adler “Real‐time tracking of the tumor volume in precision radiotherapy and body radiosurgery—A novel approach to compensate for respiratory motion ” presented at the Computer Assisted Radiology and Surgery San Francisco 2000.

10.1118/1.2739811

10.1088/0031‐9155/52/16/007

10.1088/0031‐9155/51/19/007

10.1088/0031‐9155/51/18/005

10.1088/0031‐9155/51/7/L01

10.1118/1.1833591

10.1118/1.1987967

10.1118/1.1924348

10.1118/1.2750964

10.1016/j.ijrobp.2006.04.038

10.1088/0031‐9155/46/1/301

10.1088/0031‐9155/48/5/303

10.1118/1.2905355

Zimmerman J., 2008, DMLC motion tracking of moving targets for intensity modulated arc therapy treatment—a feasibility study, Acta Oncol., 1

10.1016/j.ijrobp.2006.04.044

10.1118/1.2815934

10.1088/0031‐9155/51/14/016

10.1118/1.2372218

10.1088/0031‐9155/50/17/007

10.1088/0031‐9155/52/19/007

10.1118/1.2964090

10.1016/S0360‐3016(02)02803‐1

10.1016/j.ijrobp.2005.03.070

Murphy M. J., 2002, 539

10.1118/1.1771931

10.1118/1.2134958

10.1088/0031‐9155/49/3/006

10.1088/0031‐9155/50/12/004

10.1088/0031‐9155/47/19/302

10.1118/1.1581412

10.1088/0031‐9155/32/3/002

10.1118/1.598577

Keall P. J., 1999, A method to predict the effect of organ motion and set‐up variations on treatment plans, Australas. Phys. Eng. Sci. Med., 22, 48

10.1118/1.1589493

10.1118/1.1589492

10.1159/000106028

10.1088/0031‐9155/51/11/006

10.1016/j.ijrobp.2007.04.074

10.1093/rpd/nci225

10.1016/j.ijrobp.2008.04.018

10.1118/1.2122607

10.1016/j.ijrobp.2008.06.1937

10.1053/j.semradonc.2003.10.006

10.1016/S0360-3016(03)01056-3

10.1118/1.1539039

10.1118/1.1949749

10.1016/j.ijrobp.2004.11.037

10.1118/1.2163252

10.1118/1.1879152

10.1016/j.ijrobp.2005.12.026

10.1016/j.ijrobp.2006.10.045

10.1118/1.2739812

10.1118/1.2400612

10.1118/1.2836417

10.1088/0031‐9155/51/14/005

10.1016/j.media.2004.06.022

10.1109/TVCG.2004.2

10.1080/02841860802258760

Noe K. O., 2008, GPU accelerated viscous‐fluid deformable registration for radiotherapy, Stud. Health Technol. Inform., 132, 327

10.1088/0031‐9155/52/19/003

10.1118/1.2825616

10.1118/1.2921131

10.1118/1.2900108

10.1016/j.semradonc.2007.07.003

10.1177/153303460700600601

10.1002/1097-0142(19810701)48:1<101::AID-CNCR2820480120>3.0.CO;2-S

10.1016/S0169-5002(99)00019-7

10.1088/0031‐9155/33/1/001

10.1016/0360-3016(86)90061-1

10.1002/1097-0142(19870601)59:11<1874::AID-CNCR2820591106>3.0.CO;2-Z

10.1002/1097-0142(19800601)45:11<2744::AID-CNCR2820451108>3.0.CO;2-U

10.1016/j.ijrobp.2005.07.172

10.1016/j.ijrobp.2003.09.080

10.1016/j.ijrobp.2004.06.260

10.1016/S0360‐3016(99)00183‐2

10.1016/S0360‐3016(01)01685‐6

10.1016/S0360‐3016(98)00196‐5

10.1016/0360‐3016(95)00009‐N

10.1016/S0360‐3016(02)03986‐X

10.1016/S0360‐3016(02)02929‐2

10.1118/1.2968333

10.1016/j.ijrobp.2008.06.828

10.1016/j.ijrobp.2008.06.244

M.Uematsu CT‐guided focal high dose radiotherapy presented at the 4thS.TakahashiInternational Workshop on 3 Dimensional Conformal Radiotherapy Nagoya Japan 2004.

10.1088/0031‐9155/52/12/008

Thông tin
Thông tin xuất bản

Medical Physics

Tập 35 Số 12

5684-5694

Thông tin tác giả