LncRNA T376626 is a promising serum biomarker and promotes proliferation, migration, and invasion via binding to LAMC2 in triple-negative breast cancer

Gene - Tập 860 - Trang 147227 - 2023
Yongyin He1,2, Bin Xiao3, Ting Lei4, Junfeng Xuan1, Yi Zhu1, Zhenzhan Kuang5, Jiahui Liu1, Jia He6, Linhai Li3, Zhaohui Sun1,7
1Department of Laboratory Medicine, General Hospital of Southern Theatre Command of PLA, 510010 Guangzhou, Guangdong, China
2Department of Laboratory Medicine, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou Huiai Hospital, 510370 Guangzhou, Guangdong, China
3Department of Laboratory Medicine, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People’s Hospital, 511518 Qingyuan, Guangdong, China
4Department of Clinical Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, 519000, Zhuhai, Guangdong, China
5Department of Clinical Laboratory, South China Hospital of Shenzhen University, 518111 Shenzhen, Guangdong, China
6Guangzhou Center for Disease Control and Prevention, 510440 Guangzhou, Guangdong, China
7The First School of Clinical Medicine, Southern Medical University, 510515 Guangzhou, Guangdong, China

Tài liệu tham khảo

Wang, 2017, Identification of potential serum biomarkers for breast cancer using a functional proteomics technology, Biomarker Res., 5, 11, 10.1186/s40364-017-0092-9 Wu, 2022, A micropeptide XBP1SBM encoded by lncRNA promotes angiogenesis and metastasis of TNBC via XBP1s pathway, Oncogene, 41, 2163, 10.1038/s41388-022-02229-6 Xu, 2022, LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer, Cancer Res., 82, 556, 10.1158/0008-5472.CAN-21-1446 Lin, 2018, Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer, Mol. Cancer, 17, 84, 10.1186/s12943-018-0834-9 Zhou, 2020, Evaluation of C5orf66-AS1 as a Potential Biomarker for Predicting Early Gastric Cancer and Its Role in Gastric Carcinogenesis, OncoTargets and therapy, 13, 2795, 10.2147/OTT.S239965 Goldhirsch, 2013, Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013, Ann. Oncol. : Off. J. Eur. Soc. Medical Oncol., 24, 2206, 10.1093/annonc/mdt303 Deng, 2018, Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription, Oncogene, 37, 5811, 10.1038/s41388-018-0382-1 Wang, Y., Liu, X., Zhang, H., et al., 2014. Hypoxia-inducible lncRNA-AK058003 promotes gastric cancer metastasis by targeting γ-synuclein. Neoplasia (New York, N.Y.), 16(12), 1094–1106. Lee, 2003, Regulators of G1 cyclin-dependent kinases and cancers, Cancer Metastasis Rev., 22, 435, 10.1023/A:1023785332315 Engeland, 2018, Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM, Cell Death Differ., 25, 114, 10.1038/cdd.2017.172 Wu, 2020, Long noncoding RNA ZFAS1 promoting small nucleolar RNA-mediated 2'-O-methylation via NOP58 recruitment in colorectal cancer, Mol. Cancer, 19, 95, 10.1186/s12943-020-01201-w Jung, 2018, LAMB3 mediates metastatic tumor behavior in papillary thyroid cancer by regulating c-MET/Akt signals, Sci. Rep., 8, 2718, 10.1038/s41598-018-21216-0 Manda, 2000, Differential expression of the LAMB3 and LAMC2 genes between small cell and non-small cell lung carcinomas, Biochem. Biophys. Res. Commun., 275, 440, 10.1006/bbrc.2000.3331 Wang, 2013, Integrative analyses identify osteopontin, LAMB3 and ITGB1 as critical pro-metastatic genes for lung cancer, PLoS One, 8, e55714, 10.1371/journal.pone.0055714 Liang, 2018, LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein, Cell Death Differ., 25, 1980, 10.1038/s41418-018-0084-9 Ribeiro, 2018, Human Epididymis Protein 4 Promotes Events Associated with Metastatic Ovarian Cancer via Regulation of the Extracelluar Matrix, Front. Oncol., 7, 332, 10.3389/fonc.2017.00332 Wang, 2020, LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity, Exp. Cell Res., 391, 10.1016/j.yexcr.2020.111984 Liu, 2021, LAMC2 promotes the proliferation of cancer cells and induce infiltration of macrophages in non-small cell lung cancer, Ann. Translational Med., 9, 1392, 10.21037/atm-21-4507 Garg, 2014, Laminin-5γ-2 (LAMC2) is highly expressed in anaplastic thyroid carcinoma and is associated with tumor progression, migration, and invasion by modulating signaling of EGFR, J. Clin. Endocrinol. Metab., 99, E62, 10.1210/jc.2013-2994 Anfossi, 2018, Clinical utility of circulating non-coding RNAs - an update, Nat. Rev. Clin. Oncol., 15, 541, 10.1038/s41571-018-0035-x Zhang, 2016, Circulating lncRNA H19 in plasma as a novel biomarker for breast cancer, Cancer Biomarkers: Section A of Disease markers, 17, 187, 10.3233/CBM-160630 Fan, 2019, Comprehensive analysis of novel three-long noncoding RNA signatures as a diagnostic and prognostic biomarkers of human triple-negative breast cancer, J. Cell. Biochem., 120, 3185, 10.1002/jcb.27584 Tang, 2020, Long Noncoding RNA DCST1-AS1 Promotes Cell Proliferation and Metastasis in Triple-negative Breast Cancer by Forming a Positive Regulatory Loop with miR-873-5p and MYC, J. Cancer, 11, 311, 10.7150/jca.33982 Tong, 2015, Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma, Mol. Cancer, 14, 3, 10.1186/1476-4598-14-3 Arita, 2013, Circulating long non-coding RNAs in plasma of patients with gastric cancer, Anticancer Res, 33, 3185 Saliou, 2016, Circulating tumor DNA for triple-negative breast cancer diagnosis and treatment decisions, Expert Rev. Mol. Diagn., 16, 39, 10.1586/14737159.2016.1121100 Huang, 2020, Serum tRNA-derived fragments (tRFs) as potential candidates for diagnosis of nontriple negative breast cancer, J. Cell. Physiol., 235, 2809, 10.1002/jcp.29185 Wang, 2020, Serum lncRNA TINCR serve as a novel biomarker for predicting the prognosis in triple-negative breast cancer, Technol. Cancer Res. Treatment, 19, 10.1177/1533033820965574 Shin, 2015, Circulating cell-free miRNAs as biomarker for triple-negative breast cancer, Br. J. Cancer, 112, 1751, 10.1038/bjc.2015.143 Liu, 2017, A three-long noncoding RNA signature as a diagnostic biomarker for differentiating between triple-negative and non-triple-negative breast cancers, Medicine, 96, e6222, 10.1097/MD.0000000000006222 Liu, 2019, LncRNA AWPPH and miRNA-21 regulates cancer cell proliferation and chemosensitivity in triple-negative breast cancer by interacting with each other, J. Cell. Biochem., 120, 14860, 10.1002/jcb.28747 Bermejo, 2019, Long intergenic noncoding RNA 299 methylation in peripheral blood is a biomarker for triple-negative breast cancer, Epigenomics, 11, 81, 10.2217/epi-2018-0121 Zhang, 2019, Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT, Mol. Cancer, 18, 40, 10.1186/s12943-019-0959-5 Ren, 2019, Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia, J. Experimental Clin. Cancer Res. : CR, 38, 388, 10.1186/s13046-019-1398-2 Xue, 2017, Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1, Mol. Cancer, 16, 143, 10.1186/s12943-017-0714-8 Takahashi, 2014, Modulation of hypoxia-signaling pathways by extracellular linc-RoR, J. Cell Sci., 127, 1585 Sundqvist, 2020, TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness, Oncogene, 39, 4436, 10.1038/s41388-020-1299-z Cassandri, 2020, ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes, Oncogene, 39, 4331, 10.1038/s41388-020-1277-5 Sato, 2015, Clin. Exp. Metastasis, 32, 405, 10.1007/s10585-015-9705-6 Wang, 2011, Molecular mechanisms of long noncoding RNAs, Mol. Cell, 43, 904, 10.1016/j.molcel.2011.08.018 Zhang, 2020, LncRNA ANRIL acts as a modular scaffold of WDR5 and HDAC3 complexes and promotes alteration of the vascular smooth muscle cell phenotype, Cell Death Dis., 11, 435, 10.1038/s41419-020-2645-3 Sun, 2016, LncRNA GClnc1 promotes gastric carcinogenesis and may act as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern, Cancer Discov., 6, 784, 10.1158/2159-8290.CD-15-0921 Henning, 1999, Loss of laminin-5 in the epithelium-stroma interface: an immunohistochemical marker of malignancy in epithelial lesions of the breast, Histopathology, 34, 305, 10.1046/j.1365-2559.1999.00634.x Martin, K.J., Kwan, C.P., Nagasaki, K., et al., 1998. Down-regulation of laminin-5 in breast carcinoma cells. Molecular medicine (Cambridge, Mass.), 4(9), 602–613.