Liver diseases: A major, neglected global public health problem requiring urgent actions and large‐scale screening

Liver International - Tập 38 Số S1 - Trang 2-6 - 2018
Patrick Marcellin1, B. Kutala1
1Hepatology Department and INSERM CRI Hôpital Beaujon, APHP University Paris Diderot Clichy France

Tóm tắt

AbstractCLDs represent an important, and certainly underestimated, global public health problem. CLDs are highly prevalent and silent, related to different, sometimes associated causes. The distribution of the causes of these diseases is slowly changing, and within the next decade, the proportion of virus‐induced CLDs will certainly decrease significantly while the proportion of NASH will increase. There is an urgent need for effective global actions including education, prevention and early diagnosis to manage and treat CLDs, thus preventing cirrhosis‐related morbidity and mortality. Our role is to increase the awareness of the public, healthcare professionals and public health authorities to encourage active policies for early management that will decrease the short‐ and long‐term public health burden of these diseases. Because necroinflammation is the key mechanism in the progression of CLDs, it should be detected early. Thus, large‐scale screening for CLDs is needed. ALT levels are an easy and inexpensive marker of liver necroinflammation and could be the first‐line tool in this process.

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Liver International

Tập 38 Số S1

2-6

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