Liver X Receptor-α polymorphisms (rs11039155 and rs2279238) are associated with susceptibility to vitiligo

Meta Gene - Tập 8 - Trang 33-36 - 2016
Silky Agarwal1, Gurjinder Kaur1, Rohit Randhawa1, Vikram Mahajan2, Rohit Bansal3, Harish Changotra1
1Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan, 173 234, Himachal Pradesh, India
2Department of Dermatology, Venereology and Leprosy, Dr. Rajendra Prasad Government Medical College Kangra, Tanda 176 001, Himachal Pradesh, India
3Dr. Bansal Skin Laser Center Clinic, Board Chowk, Nac Manimajra, Chandigarh 160 002, India

Tài liệu tham khảo

Bennett, 2003, The color loci of mice—a genetic century, Pigment Cell Res., 16, 333, 10.1034/j.1600-0749.2003.00067.x Dahlman, 2009, Functional and genetic analysis in type 2 diabetes of liver X receptor alleles—a cohort study, BMC Med. Genet., 10, 27, 10.1186/1471-2350-10-27 Dahlman, 2006, Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity, Pharmacogenet. Genomics, 16, 881, 10.1097/01.fpc.0000236334.49422.48 Denat, 2014, Melanocytes as instigators and victims of oxidative stress, J. Invest. Dermatol., 134, 1512, 10.1038/jid.2014.65 Fukae, 2011, The evidence of polymorphisms of the liver X receptor gene as a DNA-based biomarker for susceptibility to coronary artery disease in a Japanese population, Acta Med. Nagasaki., 55, 69 Jamroz-Wisniewska, 2007, Liver X receptors (LXRs). Part II: non-lipid effects, role in pathology, and therapeutic implications, Postepy Hig. Med. Dosw. (Online), 61, 760 Kemp, 2001, Immunological pathomechanisms in vitiligo, Expert Rev. Mol. Med., 3, 1, 10.1017/S1462399401003362 Ketterer, 2011, Genetic variation within the NR1H2 gene encoding liver X receptor beta associates with insulin secretion in subjects at increased risk for type 2 diabetes, J. Mol. Med. (Berl.), 89, 75, 10.1007/s00109-010-0687-1 Kozak, 1987, At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells, J. Mol. Biol., 196, 947, 10.1016/0022-2836(87)90418-9 Kumar, 2012, Melanocytorrhagy and apoptosis in vitiligo: connecting jigsaw pieces, Indian J. Dermatol. Venereol. Leprol., 78, 19, 10.4103/0378-6323.90942 Kumar, 2011, Altered levels of Ets-1 transcription factor and matrix metalloproteinases in melanocytes from patients with vitiligo, Br. J. Dermatol., 165, 285, 10.1111/j.1365-2133.2011.10324.x Kumar, 2012, Altered levels of LXR-alpha: crucial implications in the pathogenesis of vitiligo, Exp. Dermatol., 21, 853, 10.1111/exd.12017 Kumar, 2010, Liver X receptor expression in human melanocytes, does it have a role in the pathogenesis of vitiligo?, Exp. Dermatol., 19, 62, 10.1111/j.1600-0625.2009.00940.x Laberge, 2005, Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo, Pigment Cell Res., 18, 300, 10.1111/j.1600-0749.2005.00242.x Lee, 2013, Liver X receptor activation inhibits melanogenesis through the acceleration of ERK-mediated MITF degradation, J. Invest. Dermatol., 133, 1063, 10.1038/jid.2012.409 Legry, 2008, Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations, Int. J. Obes., 32, 421, 10.1038/sj.ijo.0803705 Lei, 2002, In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy, Pigment Cell Res., 15, 426, 10.1034/j.1600-0749.2002.02044.x Lerner, 1959, Vitiligo, J. Invest. Dermatol., 32, 285, 10.1038/jid.1959.49 Miller, 1988, A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic Acids Res., 16, 1215, 10.1093/nar/16.3.1215 Ongenae, 2006, Psychosocial effects of vitiligo, J. Eur. Acad. Dermatol. Venereol., 20, 1, 10.1111/j.1468-3083.2005.01369.x Price, 2011, Liver X receptor alpha gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study, Pharmacogenet. Genomics, 21, 333, 10.1097/FPC.0b013e3283452fec Robitaille, 2007, The lipoprotein/lipid profile is modulated by a gene–diet interaction effect between polymorphisms in the liver X receptor-alpha and dietary cholesterol intake in French-Canadians, Br. J. Nutr., 97, 11, 10.1017/S0007114507201722 Russell, 2007, Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit, Exp. Dermatol., 16, 844, 10.1111/j.1600-0625.2007.00612.x Sabatti, 2009, Genome-wide association analysis of metabolic traits in a birth cohort from a founder population, Nat. Genet, 41, 35, 10.1038/ng.271 Shajil, 2006, Vitiligo: pathomechanisms and genetic polymorphism of susceptible genes, Indian J. Exp. Biol., 44, 526 Spritz, 2011, Recent progress in the genetics of generalized vitiligo, J. Genet. Genomics, 38, 271, 10.1016/j.jgg.2011.05.005 Steffensen, 2004, Putative metabolic effects of the liver X receptor (LXR), Diabetes, 53, S36, 10.2337/diabetes.53.2007.S36 Tang, 2013, Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population, J. Invest. Dermatol., 133, 403, 10.1038/jid.2012.320