Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
Irfan Ullah1, Jérémie Prévost2,3, Mark S. Ladinsky4, Helen Stone5, Maolin Lu5, Sai Priya Anand2,6, Guillaume Beaudoin-Bussières2,3, Kelly Symmes1, Mehdi Benlarbi2, Shilei Ding2, Romain Gasser2,3, Corby Fink7, Yaozong Chen8, Alexandra Tauzin2,3, Guillaume Goyette2, Catherine Bourassa2, Halima Medjahed2, Matthias Mack9, Kunho Chung1, Craig B. Wilen10
1Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06520, USA
2Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada
3Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC H2X 0A9, Canada
4Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA
5Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA
6Department of Microbiology and Immunology, McGill University, Montreal, QC H3A 2B4, Canada
7Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5B7, Canada
8Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
9Universitätsklinikum Regensburg, Innere Medizin II – Nephrologie, Regensburg 93042, Germany
10Departments of Laboratory Medicine and Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
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Immunity
Tập 54
2143-2158.e15
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