Lithium accelerates functional motor recovery by improving remyelination of regenerating axons following ventral root avulsion and reimplantation

Neuroscience - Tập 329 - Trang 213-225 - 2016
Xin-Yu Fang1,2, Wen-Ming Zhang3,2, Chao-Fan Zhang3,4, Wai-Man Wong2, Wen Li2, Wutian Wu2,5,6, Jian-Hua Lin3
1The First Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, China
2School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
3Department of Orthopedic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
4Department of Orthopedics & Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
5State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong Special Administrative Region
6Joint Laboratory for CNS Regeneration, Jinan University and The University of Hong Kong, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, China

Tài liệu tham khảo

Barbizan, 2013, Motor recovery and synaptic preservation after ventral root avulsion and repair with a fibrin sealant derived from snake venom, PLoS ONE, 8, e63260, 10.1371/journal.pone.0063260 Bergerot, 2004, Co-treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury, Exp Neurol, 187, 359, 10.1016/j.expneurol.2004.02.003 Bertelli, 1993, Behavioral evaluating methods in the objective clinical assessment of motor function after experimental brachial plexus reconstruction in the rat, J Neurosci Methods, 46, 203, 10.1016/0165-0270(93)90068-3 Bertelli, 1995, The grasping test: a simple behavioral method for objective quantitative assessment of peripheral nerve regeneration in the rat, J Neurosci Methods, 58, 151, 10.1016/0165-0270(94)00169-H Campbell, 2008, Evaluation and management of peripheral nerve injury, Clin Neurophysiol, 119, 1951, 10.1016/j.clinph.2008.03.018 Carlstedt, 2008, Root repair review: basic science background and clinical outcome, Restor Neurol Neurosci, 26, 225 Carlstedt, 2000, Spinal nerve root repair and reimplantation of avulsed ventral roots into the spinal cord after brachial plexus injury, J Neurosurg: Spine, 93, 237 Chadborn, 2006, PTEN couples Sema3A signalling to growth cone collapse, J Cell Sci, 119, 951, 10.1242/jcs.02801 Chai, 2000, Survival and regeneration of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion, NeuroReport, 11, 1249, 10.1097/00001756-200004270-00021 Chan, 2001, Neurotrophins are key mediators of the myelination program in the peripheral nervous system, Proc Natl Acad Sci, 98, 14661, 10.1073/pnas.251543398 Chan, 2006, The polarity protein Par-3 directly interacts with p75NTR to regulate myelination, Science (New York, NY), 314, 832, 10.1126/science.1134069 Chan, 2014, Improving peripheral nerve regeneration: from molecular mechanisms to potential therapeutic targets, Exp Neurol, 261, 826, 10.1016/j.expneurol.2014.09.006 Chu, 2008, Motor nerve graft is better than sensory nerve graft for survival and regeneration of motoneurons after spinal root avulsion in adult rats, Exp Neurol, 212, 562, 10.1016/j.expneurol.2008.05.001 Cosgaya, 2002, The neurotrophin receptor p75NTR as a positive modulator of myelination, Science (New York, NY), 298, 1245, 10.1126/science.1076595 Cullheim, 2002, Properties of motoneurons underlying their regenerative capacity after axon lesions in the ventral funiculus or at the surface of the spinal cord, Brain Res Rev, 40, 309, 10.1016/S0165-0173(02)00213-8 Dachs, 2013, Chronic treatment with lithium does not improve neuromuscular phenotype in a mouse model of severe spinal muscular atrophy, Neuroscience, 250, 417, 10.1016/j.neuroscience.2013.07.026 Dill, 2008, Inactivation of glycogen synthase kinase 3 promotes axonal growth and recovery in the CNS, J Neurosci, 28, 8914, 10.1523/JNEUROSCI.1178-08.2008 Dunham, 2003, Obstetrical brachial plexus palsy, Orthop Nurs, 22, 106, 10.1097/00006416-200303000-00007 Eickholt, 2002, An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling, J Cell Biol, 157, 211, 10.1083/jcb.200201098 El-Gammal, 2002, Outcomes of surgical treatment of brachial plexus injuries using nerve grafting and nerve transfers, J Reconstr Microsurg, 18, 7, 10.1055/s-2002-19703 Fournier, 2001, Ideal intraspinal implantation site for the repair of ventral root avulsion after brachial plexus injury in humans. A preliminary anatomical study, Surg Radiol Anat, 23, 191, 10.1007/s00276-001-0191-y Fu, 2014, Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsion, BMC Neurosci, 15, 84, 10.1186/1471-2202-15-84 Fukumoto, 2001, Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain, Psychopharmacology, 158, 100, 10.1007/s002130100871 Gao, 2005, Human neural stem cell-derived cholinergic neurons innervate muscle in motoneuron deficient adult rats, Neuroscience, 131, 257, 10.1016/j.neuroscience.2004.10.033 Garbay, 2000, Myelin synthesis in the peripheral nervous system, Prog Neurobiol, 61, 267, 10.1016/S0301-0082(99)00049-0 Gordon, 2003, Experimental strategies to promote functional recovery after peripheral nerve injuries, J Peripher Nerv Syst, 8, 236, 10.1111/j.1085-9489.2003.03029.x Gu, 2004, Survival, regeneration and functional recovery of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion, Eur J Neurosci, 19, 2123, 10.1111/j.0953-816X.2004.03295.x Gu, 2005, Survival, regeneration and functional recovery of motoneurons after delayed reimplantation of avulsed spinal root in adult rat, Exp Neurol, 192, 89, 10.1016/j.expneurol.2004.10.019 Hallin, 1999, Spinal cord implantation of avulsed ventral roots in primates; correlation between restored motor function and morphology, Exp Brain Res, 124, 304, 10.1007/s002210050627 Haninec, 2004, Exp Brain Res, 159, 425, 10.1007/s00221-004-1969-z Hashimoto, 2002, Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity, Neuropharmacology, 43, 1173, 10.1016/S0028-3908(02)00217-4 Hoke, 2006, Mechanisms of disease: what factors limit the success of peripheral nerve regeneration in humans?, Nat Clin Pract Neuro, 2, 448, 10.1038/ncpneuro0262 Huzé, 2009, Identification of an agrin mutation that causes congenital myasthenia and affects synapse function, Am J Hum Genet, 85, 155, 10.1016/j.ajhg.2009.06.015 Inciong, 2000, Efficacy of intervention strategies in a brachial plexus global avulsion model in the rat, Plast Reconstr Surg, 105, 2059, 10.1097/00006534-200005000-00021 Ito, 2006, Sema4D/plexin-B1 activates GSK-3β through R-Ras GAP activity, inducing growth cone collapse, EMBO Rep, 7, 704, 10.1038/sj.embor.7400737 Jiang, 2005, Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3β and its upstream regulators, Cell, 120, 123 Lang, 2008, Single-dose application of CNTF and BDNF improves remyelination of regenerating nerve fibers after C7 ventral root avulsion and replantation, J Neurotrauma, 25, 384, 10.1089/neu.2007.0396 Makoukji, 2012, Lithium enhances remyelination of peripheral nerves, Proc Natl Acad Sci U S A, 109, 3973, 10.1073/pnas.1121367109 Meffre, 2014, Wnt and lithium: a common destiny in the therapy of nervous system pathologies?, Cell Mol Life Sci, 71, 1123, 10.1007/s00018-013-1378-1 Mills, 2003, Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth, J Neurosci, 23, 1638, 10.1523/JNEUROSCI.23-05-01638.2003 Namgung, 2015, The role of Schwann cell-axon interaction in peripheral nerve regeneration, Cells Tissues Organs, 10.1159/000370324 Nouri, 2009, Lithium improves regeneration after sciatic nerve traumatic injury in rat, J Reconstr Microsurg, 25, 151, 10.1055/s-0028-1103504 Raafat, 2014, Role of EMG and nerve conduction studies in the management of traumatic peripheral nerve injuries, Egyptian J Neurol Psychiatry Neurosurg, 51 Read, 2009, Involvement of Akt in neurite outgrowth, Cell Mol Life Sci, 66, 2975, 10.1007/s00018-009-0057-8 Sharp, 2014, A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury, Exp Neurol, 257, 186, 10.1016/j.expneurol.2014.04.008 Slutsky, 2003, Activation of myelin genes during transdifferentiation from melanoma to glial cell phenotype, J Biol Chem, 278, 8960, 10.1074/jbc.M210569200 Su, 2009, Neural progenitor cells enhance the survival and axonal regeneration of injured motoneurons after transplantation into the avulsed ventral horn of adult rats, J Neurotrauma, 26, 67, 10.1089/neu.2008.0656 Su, 2014, Lithium enhances axonal regeneration in peripheral nerve by inhibiting glycogen synthase kinase 3 beta activation, BioMed Res Int, 2014, 658753, 10.1155/2014/658753 Tawk, 2011, Wnt/β-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis, J Neurosci, 31, 3729, 10.1523/JNEUROSCI.4270-10.2011 Terzis, 1999, Outcomes of brachial plexus reconstruction in 204 patients with devastating paralysis, Plast Reconstr Surg, 104, 1221, 10.1097/00006534-199910000-00001 Tung, 2003, Brachial plexus injuries, Clin Plast Surg, 30, 269, 10.1016/S0094-1298(02)00094-9 Voyvodic JT (1989) Target size regulates calibre and myelination of sympathetic axons. Wilhelm, 2012, Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration, J Neurosci, 32, 5002, 10.1523/JNEUROSCI.1411-11.2012 Wu, 1996, Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: a comparison among c-jun, low-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS), Exp Neurol, 141, 190, 10.1006/exnr.1996.0153 Yick, 2004, Lithium chloride reinforces the regeneration-promoting effect of chondroitinase ABC on rubrospinal neurons after spinal cord injury, J Neurotrauma, 21, 932, 10.1089/0897715041526221 Zhou, 2004, NGF-induced axon growth is mediated by localized inactivation of GSK-3β and functions of the microtubule plus end binding protein APC, Neuron, 42, 897, 10.1016/j.neuron.2004.05.011