Các Hạt Nan Dựa Trên Lipid: Ứng Dụng và Những Tiến Bộ Gần Đây Trong Điều Trị Ung Thư

Bor, 2019, Nanomedicines for cancer therapy: Current status, challenges and future prospects, Ther. Deliv., 10, 113, 10.4155/tde-2018-0062

Miele, 2012, Nanoparticle-based delivery of small interfering RNA: Challenges for cancer therapy, Int. J. Nanomed., 7, 3637

Cormode, 2014, Nanoparticle contrast agents for computed tomography: A focus on micelles, Contrast Media Mol. Imaging, 9, 37, 10.1002/cmmi.1551

Ozpolat, 2014, Liposomal siRNA nanocarriers for cancer therapy, Adv. Drug Deliv. Rev., 66, 110, 10.1016/j.addr.2013.12.008

Rama, 2016, Last Advances in Nanocarriers-Based Drug Delivery Systems for Colorectal Cancer, Curr. Drug Deliv., 13, 830, 10.2174/1567201813666151203232852

Alavi, M., and Hamidi, M. (2019). Passive and active targeting in cancer therapy by liposomes and lipid nanoparticles. Drug Metab. Pers. Ther., 34.

Yingchoncharoen, 2016, Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come, Pharmacol. Rev., 68, 701, 10.1124/pr.115.012070

Holban, A.M., and Grumezescu, A.M. (2016). 27—Multifunctional Magnetic Liposomes for Cancer Imaging and Therapeutic Applications. Nanoarchitectonics for Smart Delivery and Drug Targeting, William Andrew Publishing.

Kunjachan, 2015, Noninvasive Imaging of Nanomedicines and Nanotheranostics: Principles, Progress, and Prospects, Chem. Rev., 115, 10907, 10.1021/cr500314d

Hardiansyah, 2014, Magnetic liposomes for colorectal cancer cells therapy by high-frequency magnetic field treatment, Nanoscale Res. Lett., 9, 497, 10.1186/1556-276X-9-497

Park, 2014, Hyaluronic acid derivative-coated nanohybrid liposomes for cancer imaging and drug delivery, J. Control. Release, 174, 98, 10.1016/j.jconrel.2013.11.016

Ninomiya, 2014, Ultrasound-mediated drug delivery using liposomes modified with a thermosensitive polymer, Ultrason. Sonochem., 21, 310, 10.1016/j.ultsonch.2013.07.014

Legut, 2014, Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines-in vitro studies, Int. J. Nanomed., 9, 653

Yan, 2015, A pH-Responsive Drug-Delivery Platform Based on Glycol Chitosan-Coated Liposomes, Small, 11, 4870, 10.1002/smll.201501412

Ramadass, 2015, Paclitaxel/epigallocatechin gallate coloaded liposome: A synergistic delivery to control the invasiveness of MDA-MB-231 breast cancer cells, Colloids Surf. B Biointerfaces, 125, 65, 10.1016/j.colsurfb.2014.11.005

Ali, 2016, Bioequivalence Study of Pegylated Doxorubicin Hydrochloride Liposome (PEGADRIA) and DOXIL® in Ovarian Cancer Patients: Physicochemical Characterization and Pre-clinical Studies, J. Nanomed. Nanotechnol., 7, 2

Meng, 2016, Combination Therapy using Co-encapsulated Resveratrol and Paclitaxel in Liposomes for Drug Resistance Reversal in Breast Cancer Cells in vivo, Sci. Rep., 6, 22390, 10.1038/srep22390

Xiao, 2016, Sorafenib and gadolinium co-loaded liposomes for drug delivery and MRI-guided HCC treatment, Colloids Surf. B Biointerfaces, 141, 83, 10.1016/j.colsurfb.2016.01.016

Lakkadwala, 2018, Dual Functionalized 5-Fluorouracil Liposomes as Highly Efficient Nanomedicine for Glioblastoma Treatment as Assessed in an In Vitro Brain Tumor Model, J. Pharm. Sci., 107, 2902, 10.1016/j.xphs.2018.07.020

Deshpande, 2018, Transferrin and octaarginine modified dual-functional liposomes with improved cancer cell targeting and enhanced intracellular delivery for the treatment of ovarian cancer, Drug Deliv., 25, 517, 10.1080/10717544.2018.1435747

Sesarman, 2019, Co-delivery of curcumin and doxorubicin in PEGylated liposomes favored the antineoplastic C26 murine colon carcinoma microenvironment, Drug Deliv. Transl. Res., 9, 260, 10.1007/s13346-018-00598-8

Tian, 2018, Overcoming drug-resistant lung cancer by paclitaxel-loaded hyaluronic acid-coated liposomes targeted to mitochondria, Drug Dev. Ind. Pharm., 44, 2071, 10.1080/03639045.2018.1512613

Mydin, R.B.S.M.N., and Moshawih, S. (2007). Nanoparticles in Nanomedicine Application: Lipid-Based Nanoparticles and Their Safety Concerns. Nanotechnology: Applications in Energy, Drug and Food, Springer.

Rajabi, 2016, Lipid Nanoparticles and their Application in Nanomedicine, Curr. Pharm. Biotechnol., 17, 662, 10.2174/1389201017666160415155457

Pindiprolu, 2018, Formulation-optimization of solid lipid nanocarrier system of STAT3 inhibitor to improve its activity in triple negative breast cancer cells, Drug Dev. Ind. Pharm., 45, 304, 10.1080/03639045.2018.1539496

Eskiler, 2018, Synthetically Lethal BMN 673 (Talazoparib) Loaded Solid Lipid Nanoparticles for BRCA1 Mutant Triple Negative Breast Cancer, Pharm. Res., 35, 218, 10.1007/s11095-018-2502-6

Oliveira, 2018, Triggered release of paclitaxel from magnetic solid lipid nanoparticles by magnetic hyperthermia, Mater. Sci. Eng. C, 92, 547, 10.1016/j.msec.2018.07.011

Ferreira, 2018, Anti-inflammatory and anti-cancer activity of citral: Optimization of citral-loaded solid lipid nanoparticles (SLN) using experimental factorial design and LUMiSizer®, Int. J. Pharm., 553, 428, 10.1016/j.ijpharm.2018.10.065

Wang, W., Zhang, L., Chen, T., Guo, W., Bao, X., Wang, D., Ren, B., Wang, H., Li, Y., and Wang, Y. (2017). Anticancer effects of resveratrol-loaded solid lipid nanoparticles on human breast cancer cells. Molecules, 22.

Chirio, 2018, Lipophilic Prodrug of Floxuridine Loaded into Solid Lipid Nanoparticles: In Vitro Cytotoxicity Studies on Different Human Cancer Cell Lines, J. Nanosci. Nanotechnol., 18, 556, 10.1166/jnn.2018.13964

Rahiminejad, 2018, Preparation and investigation of Indirubin-loaded SLN nanoparticles and their anti-cancer effects on human glioblastoma U87MG cells, Cell Boil. Int., 43, 2, 10.1002/cbin.11037

Obeid, M.A., Tate, R.J., Mullen, A.B., and Ferro, V.A. (2018). Lipid-Based Nanoparticles for Cancer Treatment, Elsevier Inc.

Fahmy, 2018, Augmentation of Fluvastatin Cytotoxicity Against Prostate Carcinoma PC3 Cell Line Utilizing Alpha Lipoic–Ellagic Acid Nanostructured Lipid Carrier Formula, AAPS PharmSciTech, 19, 3454, 10.1208/s12249-018-1199-5

Haron, 2018, Cytotoxic Effect of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) on Liver Cancer Cell Integrated with Hepatitis B Genome, Hep3B, Evid.-Based Complement. Altern. Med., 2018, 1549805, 10.1155/2018/1549805

Li, 2018, Construction of artesunate nanoparticles modified by hyaluronic acid and cell-penetrating peptides and its inhibitory effect on cancer cells in vitro, China J. Chin. Mater. Med., 43, 3668

Nahak, 2018, Orcinol Glucoside Loaded Polymer-Lipid Hybrid Nanostructured Lipid Carriers: Potential Cytotoxic Agents against Gastric, Colon and Hepatoma Carcinoma Cell Lines, Pharm. Res., 35, 198, 10.1007/s11095-018-2469-3

Wei, 2018, Formulation, Characterization, and Pharmacokinetic Studies of 6-Gingerol-Loaded Nanostructured Lipid Carriers, AAPS PharmSciTech, 19, 3661, 10.1208/s12249-018-1165-2

Silva, C., Pinho, J., Lopes, J., Almeida, A., Gaspar, M., and Reis, C. (2019). Current Trends in Cancer Nanotheranostics: Metallic, Polymeric, and Lipid-Based Systems. Pharmaceutics, 11.

Sharma, 2019, Advances in nanocarriers enabled brain targeted drug delivery across blood brain barrier, Int. J. Pharm., 559, 360, 10.1016/j.ijpharm.2019.01.056

Tapeinos, 2017, Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases, J. Control. Release, 264, 306, 10.1016/j.jconrel.2017.08.033

Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 68, 394, 10.3322/caac.21492

Ferlay, 2019, Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods, Int. J. Cancer, 144, 1941, 10.1002/ijc.31937

Palesh, 2018, Management of side effects during and post-treatment in breast cancer survivors, Breast J., 24, 167, 10.1111/tbj.12862

Numico, 2015, Cancer survivorship: Long-term side-effects of anticancer treatments of gastrointestinal cancer, Curr. Opin. Oncol., 27, 351, 10.1097/CCO.0000000000000203

Tang, 2018, Cancer theranostic applications of lipid-based nanoparticles, Drug Discov. Today, 23, 1159, 10.1016/j.drudis.2018.04.007

Raucher, 2018, Macromolecular Drug Carriers for Targeted Glioblastoma Therapy: Preclinical Studies, Challenges, and Future Perspectives, Front. Oncol., 8, 624, 10.3389/fonc.2018.00624

Angelova, 2017, Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents, Adv. Colloid Interface Sci., 249, 331, 10.1016/j.cis.2017.04.006

Yaari, 2016, Theranostic barcoded nanoparticles for personalized cancer medicine, Nat. Commun., 7, 13325, 10.1038/ncomms13325

Ding, 2015, Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer, Oncol. Rep., 34, 1825, 10.3892/or.2015.4142

Yang, 2018, SATB1 siRNA-encapsulated immunoliposomes conjugated with CD44 antibodies target and eliminate gastric cancer-initiating cells, Onco Targets Ther., 11, 6811, 10.2147/OTT.S182437

Wonder, 2018, Competition of charge-mediated and specific binding by peptide-tagged cationic liposome–DNA nanoparticles in vitro and in vivo, Biomaterials, 166, 52, 10.1016/j.biomaterials.2018.02.052

Wang, 2014, Intracellular uptake of etoposide-loaded solid lipid nanoparticles induces an enhancing inhibitory effect on gastric cancer through mitochondria-mediated apoptosis pathway, Int. J. Nanomed., 9, 3987, 10.2147/IJN.S64103

Li, 2017, miR-542-3p Appended Sorafenib/All-trans Retinoic Acid (ATRA)-Loaded Lipid Nanoparticles to Enhance the Anticancer Efficacy in Gastric Cancers, Pharm. Res., 34, 2710, 10.1007/s11095-017-2202-7

Ma, 2018, Co-delivery of paclitaxel and tanespimycin in lipid nanoparticles enhanced anti-gastric-tumor effect in vitro and in vivo, Artif. Cells Nanomed. Biotechnol., 46, 904, 10.1080/21691401.2018.1472101

Jiang, 2015, Etoposide-loaded nanostructured lipid carriers for gastric cancer therapy, Drug Deliv., 23, 1379, 10.3109/10717544.2015.1048491

Jiang, 2016, Co-delivery of etoposide and curcumin by lipid nanoparticulate drug delivery system for the treatment of gastric tumors, Drug Deliv., 23, 3665, 10.1080/10717544.2016.1217954

Qu, 2015, Engineering of lipid prodrug-based, hyaluronic acid-decorated nanostructured lipid carriers platform for 5-fluorouracil and cisplatin combination gastric cancer therapy, Int. J. Nanomed., 10, 3911

Chang, 2015, External beam radiotherapy synergizes 188Re-liposome against human esophageal cancer xenograft and modulates 188Re-liposome pharmacokinetics, Int. J. Nanomed., 10, 3641

Feng, 2018, Autophagy Inhibitor (LY294002) and 5-fluorouracil (5-FU) Combination-Based Nanoliposome for Enhanced Efficacy Against Esophageal Squamous Cell Carcinoma, Nanoscale Res. Lett., 13, 325, 10.1186/s11671-018-2716-x

Wang, 2016, In situ delivery of thermosensitive gel-mediated 5-fluorouracil microemulsion for the treatment of colorectal cancer, Drug Des. Dev. Ther., 10, 2855, 10.2147/DDDT.S111351

Low, 2019, Magnetic cellulose nanocrystal stabilized Pickering emulsions for enhanced bioactive release and human colon cancer therapy, Int. J. Biol. Macromol., 127, 76, 10.1016/j.ijbiomac.2019.01.037

Ektate, 2018, Chemo-immunotherapy of colon cancer with focused ultrasound and Salmonella-laden temperature sensitive liposomes (thermobots), Sci. Rep., 8, 13062, 10.1038/s41598-018-30106-4

Moghimipour, 2018, Folic acid-modified liposomal drug delivery strategy for tumor targeting of 5-fluorouracil, Eur. J. Pharm. Sci., 114, 166, 10.1016/j.ejps.2017.12.011

Kassem, 2017, Maximizing the Therapeutic Efficacy of Imatinib Mesylate–Loaded Niosomes on Human Colon Adenocarcinoma Using Box-Behnken Design, J. Pharm. Sci., 106, 111, 10.1016/j.xphs.2016.07.007

Serini, S., Cassano, R., Corsetto, P.A., Rizzo, A.M., Calviello, G., and Trombino, S. (2018). Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro. Int. J. Mol. Sci., 19.

Shen, 2019, Hierarchically targetable polysaccharide-coated solid lipid nanoparticles as an oral chemo/thermotherapy delivery system for local treatment of colon cancer, Biomaterials, 197, 86, 10.1016/j.biomaterials.2019.01.019

Negi, 2014, Surface engineered nanostructured lipid carriers for targeting MDR tumor: Part I. Synthesis, characterization and in vitro investigation, Colloids Surf. B Biointerfaces, 123, 600, 10.1016/j.colsurfb.2014.09.062

Chirio, D., Peira, E., Sapino, S., Dianzani, C., Barge, A., Muntoni, E., Morel, S., and Gallarate, M. (2018). Stearoyl-Chitosan Coated Nanoparticles Obtained by Microemulsion Cold Dilution Technique. Int. J. Mol. Sci., 19.

Nazzal, 2017, Gemcitabine-vitamin E conjugates: Synthesis, characterization, entrapment into nanoemulsions, and in-vitro deamination and antitumor activity, Int. J. Pharm., 528, 463, 10.1016/j.ijpharm.2017.06.031

Wood, 2018, Oseltamivir phosphate released from injectable Pickering emulsions over an extended term disables human pancreatic cancer cell survival, Oncotarget, 9, 12754, 10.18632/oncotarget.24339

Bisht, 2016, A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: Towards future combination therapies, J. Nanobiotechnol., 14, 57, 10.1186/s12951-016-0209-6

Wei, 2017, Thermosensitive Liposomal Codelivery of HSA–Paclitaxel and HSA–Ellagic Acid Complexes for Enhanced Drug Perfusion and Efficacy Against Pancreatic Cancer, ACS Appl. Mater. Interfaces, 9, 25138, 10.1021/acsami.7b07132

Glassman, D.C., Palmaira, R.L., Covington, C.M., Desai, A.M., Ku, G.Y., Li, J., Harding, J.J., Varghese, A.M., O’Reilly, E.M., and Yu, K.H. (2018). Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience. BMC Cancer, 18.

Li, 2016, Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): A global, randomised, open-label, phase 3 trial, Lancet, 387, 545, 10.1016/S0140-6736(15)00986-1

Barkat, 2019, Paclitaxel-loaded Nanolipidic Carriers with Improved Oral Bioavailability and Anticancer Activity against Human Liver Carcinoma, AAPS PharmSciTech, 20, 87, 10.1208/s12249-019-1304-4

Nasr, 2015, In vitro and in vivo evaluation of cubosomes containing 5-fluorouracil for liver targeting, Acta Pharm. Sin. B, 5, 79, 10.1016/j.apsb.2014.12.001

Grillone, 2015, Active Targeting of Sorafenib: Preparation, Characterization, and In Vitro Testing of Drug-Loaded Magnetic Solid Lipid Nanoparticles, Adv. Healthc. Mater., 4, 1681, 10.1002/adhm.201500235

Lin, 2014, Preparation of curcumin microemulsions with food-grade soybean oil/lecithin and their cytotoxicity on the HepG2 cell line, Food Chem., 154, 282, 10.1016/j.foodchem.2014.01.012

Qu, 2017, Octanoyl galactose ester-modified microemulsion system self-assembled by coix seed components to enhance tumor targeting and hepatoma therapy, Int. J. Nanomed., 12, 2045, 10.2147/IJN.S125293

Hu, 2017, Nanocolloidosomes with Selective Drug Release for Active Tumor-Targeted Imaging-Guided Photothermal/Chemo Combination Therapy, Appl. Mater. Interfaces, 9, 42225, 10.1021/acsami.7b14796

Zhang, X., Lin, C.-C., Chan, W.-K.-N., Liu, K.-L., Yang, Z.-J., and Zhang, H.-Q. (2017). Augmented Anticancer Effects of Cantharidin with Liposomal Encapsulation: In Vitro and In Vivo Evaluation. Molecules, 22.

Chang, 2018, Antitumor activities of novel glycyrrhetinic acid-modified curcumin-loaded cationic liposomes in vitro and in H22 tumor-bearing mice, Drug Deliv., 25, 1984, 10.1080/10717544.2018.1526227

Beg, 2017, Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors, Investig. New Drugs, 35, 180, 10.1007/s10637-016-0407-y

Sasmita, 2018, Biomarkers and therapeutic advances in glioblastoma multiforme, Asia Pac. J. Clin. Oncol., 14, 40, 10.1111/ajco.12756

Kumar, 2016, Curcumin-loaded lipid nanocarrier for improving bioavailability, stability and cytotoxicity against malignant glioma cells, Drug Deliv., 23, 214, 10.3109/10717544.2014.909906

Shinde, 2017, Docosahexaenoic acid-mediated, targeted and sustained brain delivery of curcumin microemulsion, Drug Deliv., 24, 152, 10.1080/10717544.2016.1233593

Lakkadwala, 2019, Co-delivery of doxorubicin and erlotinib through liposomal nanoparticles for glioblastoma tumor regression using an in vitro brain tumor model, Colloids Surf. B Biointerfaces, 173, 27, 10.1016/j.colsurfb.2018.09.047

Kadari, 2018, Design of multifunctional peptide collaborated and docetaxel loaded lipid nanoparticles for antiglioma therapy, Eur. J. Pharm. Biopharm., 132, 168, 10.1016/j.ejpb.2018.09.012

Carbone, 2014, FA-loaded lipid drug delivery systems: Preparation, characterization and biological studies, Eur. J. Pharm. Sci., 52, 12, 10.1016/j.ejps.2013.10.003

Zhang, 2018, Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy, Int. J. Nanomed., 13, 3039, 10.2147/IJN.S161163

Papachristodoulou, 2019, Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes, J. Control. Release, 295, 130, 10.1016/j.jconrel.2018.12.009

Chastagner, 2015, Phase I study of non-pegylated liposomal doxorubicin in children with recurrent/refractory high-grade glioma, Cancer Chemother. Pharmacol., 76, 425, 10.1007/s00280-015-2781-0

Clarke, 2017, A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma, Cancer Chemother. Pharmacol., 79, 603, 10.1007/s00280-017-3247-3

Jyoti, 2015, Inhalable nanostructured lipid particles of 9-bromo-noscapine, a tubulin-binding cytotoxic agent: In vitro and in vivo studies, J. Colloid Interface Sci., 445, 219, 10.1016/j.jcis.2014.12.092

Sun, 2016, Functional nanoemulsion-hybrid lipid nanocarriers enhance the bioavailability and anti-cancer activity of lipophilic diferuloylmethane, Nanotechnology, 27, 085102, 10.1088/0957-4484/27/8/085102

Wan, 2016, Novel nanoemulsion based lipid nanosystems for favorable in vitro and in vivo characteristics of curcumin, Int. J. Pharm., 504, 80, 10.1016/j.ijpharm.2016.03.055

Asmawi, 2018, Excipient selection and aerodynamic characterization of nebulized lipid-based nanoemulsion loaded with docetaxel for lung cancer treatment, Drug Deliv. Transl. Res., 9, 543, 10.1007/s13346-018-0526-4

Chen, 2018, A comparison study between lycobetaine-loaded nanoemulsion and liposome using nRGD as therapeutic adjuvant for lung cancer therapy, Eur. J. Pharm. Sci., 111, 293, 10.1016/j.ejps.2017.09.041

Shi, 2014, Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression, J. Control. Release, 194, 228, 10.1016/j.jconrel.2014.09.005

Li, 2017, Combination lung cancer chemotherapy: Design of a pH-sensitive transferrin-PEG-Hz-lipid conjugate for the co-delivery of docetaxel and baicalin, Biomed. Pharmacother., 95, 548, 10.1016/j.biopha.2017.08.090

Liang, 2017, Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer, Int. J. Nanomed., 12, 1699, 10.2147/IJN.S121262

Lu, 2015, Intratumoral chemotherapy with paclitaxel liposome combined with systemic chemotherapy: A new method of neoadjuvant chemotherapy for stage III unresectable non-small cell lung cancer, Med. Oncol., 32, 345, 10.1007/s12032-014-0345-5

Cao, 2015, Coencapsulated doxorubicin and bromotetrandrine lipid nanoemulsions in reversing multidrug resistance in breast cancer in vitro and in vivo, Mol. Pharm., 12, 274, 10.1021/mp500637b

Rocca, 2017, Phase Ib dose-finding trial of lapatinib plus pegylated liposomal doxorubicin in advanced HER2-positive breast cancer, Cancer Chemother. Pharmacol., 79, 863, 10.1007/s00280-017-3279-8

Lorusso, 2014, Non-pegylated liposome-encapsulated doxorubicin citrate plus cyclophosphamide or vinorelbine in metastatic breast cancer not previously treated with chemotherapy: A multicenter phase III study, Int. J. Oncol., 45, 2137, 10.3892/ijo.2014.2604

Behroozah, 2018, Evaluation the Anti-Cancer Effect of PEGylated Nano-Niosomal Gingerol, on Breast Cancer Cell lines (T47D), In-Vitro, Asian Pac. J. Cancer Prev., 19, 645

Salem, 2018, Evaluation and optimization of pH-responsive niosomes as a carrier for efficient treatment of breast cancer, Drug Deliv. Transl. Res., 8, 633, 10.1007/s13346-018-0499-3

Shaker, 2015, Cellular uptake, cytotoxicity and in-vivo evaluation of Tamoxifen citrate loaded niosomes, Int. J. Pharm., 493, 285, 10.1016/j.ijpharm.2015.07.041

Davarpanah, 2018, Magnetic delivery of antitumor carboplatin by using PEGylated-Niosomes, DARU J. Pharm. Sci., 26, 57, 10.1007/s40199-018-0215-3

Amiri, 2016, Preparation, Characterization and Cytotoxicity of Silibinin-Containing Nanoniosomes in T47D Human Breast Carcinoma Cells, Asian Pac. J. Cancer Prev., 17, 3835

Moghassemi, 2018, Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line, Artif. Cells Nanomed. Biotechnol., 46, 524, 10.1080/21691401.2017.1326928

Barani, 2018, Lawsone-loaded Niosome and its antitumor activity in MCF-7 breast Cancer cell line: A Nano-herbal treatment for Cancer, DARU J. Pharm. Sci., 26, 11, 10.1007/s40199-018-0207-3

Tila, 2015, pH-sensitive, polymer modified, plasma stable niosomes: Promising carriers for anti-cancer drugs, EXCLI J., 14, 21

Rajput, 2015, Overcoming Akt Induced Therapeutic Resistance in Breast Cancer through siRNA and Thymoquinone Encapsulated Multilamellar Gold Niosomes, Mol. Pharm., 12, 4214, 10.1021/acs.molpharmaceut.5b00692

Alavi, 2014, Archaeosome: As new drug carrier for delivery of Paclitaxel to breast cancer, Indian J. Clin. Biochem., 29, 150, 10.1007/s12291-013-0305-4

Tian, 2017, Folic Acid-Targeted Etoposide Cubosomes for Theranostic Application of Cancer Cell Imaging and Therapy, Med. Sci. Monit., 23, 2426, 10.12659/MSM.904683

Yu, 2016, Anti-tumor efficiency of paclitaxel and DNA when co-delivered by pH responsive ligand modified nanocarriers for breast cancer treatment, Biomed. Pharmacother., 83, 1428, 10.1016/j.biopha.2016.08.061

Garg, 2016, Fucose decorated solid-lipid nanocarriers mediate efficient delivery of methotrexate in breast cancer therapeutics, Colloids Surf. B Biointerfaces, 146, 114, 10.1016/j.colsurfb.2016.05.051

Liang, 2018, Cascaded Aptamers-Governed Multistage Drug-Delivery System Based on Biodegradable Envelope-Type Nanovehicle for Targeted Therapy of HER2-Overexpressing Breast Cancer, ACS Appl. Mater. Interfaces, 10, 34050, 10.1021/acsami.8b14009

Li, 2018, Nanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy, Int. J. Nanomed., 13, 4107, 10.2147/IJN.S163929

Ahmad, 2017, Nanoemulsion Formulation of a Novel Taxoid DHA-SBT-1214 Inhibits Prostate Cancer Stem Cell-Induced Tumor Growth, Cancer Lett., 406, 71, 10.1016/j.canlet.2017.08.004

Chen, 2016, Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3, Int. J. Nanomed., 11, 1907, 10.2147/IJN.S103759

Nassir, 2019, Surface functionalized folate targeted oleuropein nano-liposomes for prostate tumor targeting: Invitro and invivo activity, Life Sci., 220, 136, 10.1016/j.lfs.2019.01.053

Hua, 2017, Multifunctional gold nanorods and docetaxel-encapsulated liposomes for combined thermo- and chemotherapy, Int. J. Nanomed., 12, 7869, 10.2147/IJN.S143977

Saber, M.M., Al-Mahallawi, A.M., Nassar, N.N., Stork, B., and Shouman, S.A. (2018). Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes. BMC Cancer, 18.

Sarookhani, 2018, Molecular mechanisms of drug resistance in ovarian cancer, J. Cell. Physiol., 233, 4546, 10.1002/jcp.26289

Pan, 2016, Molecular mechanisms for tumour resistance to chemotherapy, Clin. Exp. Pharmacol. Physiol., 43, 723, 10.1111/1440-1681.12581

Baek, 2017, A multifunctional lipid nanoparticle for co-delivery of paclitaxel and curcumin for targeted delivery and enhanced cytotoxicity in multidrug resistant breast cancer cells, Oncotarget, 8, 30369, 10.18632/oncotarget.16153

Cobaleda, 2013, Function of oncogenes in cancer development: A changing paradigm, EMBO J., 32, 1502, 10.1038/emboj.2013.97

Zhao, 2016, PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery, Nat. Commun., 7, 11822, 10.1038/ncomms11822

Prieto-Vila, M., Takahashi, R., Usuba, W., Kohama, I., and Ochiya, T. (2017). Drug Resistance Driven by Cancer Stem Cells and Their Niche. Int. J. Mol. Sci., 18.

Li, 2019, In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis, Biomaterials, 188, 160, 10.1016/j.biomaterials.2018.10.019