Linkage graphs: a study in the thermodynamics of macromolecules

Quarterly Reviews of Biophysics - Tập 17 Số 4 - Trang 453-488 - 1984
Jeffries Wyman1
1CNR Center for Molecular Biology, Istituto di Chimica Facoltà di Medicina, Università di Roma I 00185 Rome Italy, and Department of Chemistry, University of Colorado, Boulder, CO 80309

Tóm tắt

In earlier papers (Wyman, 1975a, b, 1981) I have called attention to the existence of a group of linkage potentials derivable from one another by a corresponding group of Legendre transformations. These potentials are applicable to any system in a state of equilibrium but are especially useful in the study of the behaviour, or, as we may say, the functional chemistry, of a macromolecule in the presence of its ligands. In this paper I show how these potentials may be represented by a set of contour graphs which embody the results of observation and are transformable into one another by a group of graphical permutations equivalent to the Legendre group.

Từ khóa


Tài liệu tham khảo

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Quarterly Reviews of Biophysics

Tập 17 Số 4

453-488

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