Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation

Bioorganic & Medicinal Chemistry - Tập 14 - Trang 5489-5502 - 2006
Shinnosuke Hosoda1, Aya Tanatani1, Ken-ichi Wakabayashi1, Makoto Makishima2, Keisuke Imai3, Hiroyuki Miyachi1, Kazuo Nagasawa4, Yuichi Hashimoto1
1Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan
2Department of Biochemistry, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan
3Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan
4Department of Biotechnology and Life Science, Faculty of Technology, Tokyo University of Agriculture and Technology, 2-24-16 Naka-machi, Koganei-shi, Tokyo 184-8588, Japan

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