Lifetime Prevalence, Age of Risk, and Genetic Relationships of Comorbid Psychiatric Disorders in Tourette Syndrome

JAMA Psychiatry - Tập 72 Số 4 - Trang 325 - 2015
Matthew E. Hirschtritt1, Paul C. Lee2, David L. Pauls2, Yves Dion3, Marco A. Grados4, Cornelia Illmann2, Robert A. King5, Paul Sandor6,7,8, William M. McMahon9, Gholson J. Lyon10, Daniëlle C. Cath11,12, Roger Kurlan13, Mary M. Robertson14,15, Lisa Osiecki2, Jeremiah M. Scharf16,17,18,19, Carol A. Mathews1
1Program for Genetics and Epidemiology of Neuropsychiatric Symptoms, Department of Psychiatry, University of California, San Francisco
2Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Harvard Medical School, Massachusetts General Hospital, Boston
3Department of Psychiatry, University of Montreal, Montreal, Quebec, Canada
4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland
5Yale Child Study Center, Department of Genetics, Yale University School of Medicine, New Haven, Connecticut
6Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
7Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada7University Health Network, Toronto Western Research Institute, Toronto, Ontario, Canada8Youthdale Treatment Centers, Toronto, Ontario, Canada
8Youthdale Treatment Centers, Toronto, Ontario, Canada
9Department of Psychiatry, University of Utah, Salt Lake City
10Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Woodbury, New York
11Altrecht Academic Anxiety Disorders Centre, Utrecht, The Netherlands
12Department of Clinical and Health Psychology, Utrecht University, Utrecht, the Netherlands12Altrecht Academic Anxiety Disorders Centre, Utrecht, the Netherlands
13Atlantic Neuroscience Institute, Overlook Hospital, Summit, New Jersey
14University College London, London, England
15University College London, London, England15St George’s Hospital and Medical School, London, England16Department of Psychiatry, University of Cape Town, Cape Town, South Africa
16Department of Neurology, Massachusetts General Hospital, Boston
17Department of Psychiatry, Massachusetts General Hospital, Boston
18Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Harvard Medical School, Massachusetts General Hospital, Boston17Stanley Center for Psychiatric Research, Broad Institute of Harvard and Massachusetts Institute of Techno
19Stanley Center for Psychiatric Research, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts

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