Life Extension Properties of Superoxide Dismutase Mimics Arise from “Calorie Restriction”

Chemistry & Biology - Tập 10 - Trang 197-198 - 2003
Declan Patrick Naughton1, Anna E Fisher1
1School of Pharmacy and Biomolecular Science, University of Brighton, Lewes Road, Brighton, BN2 4GJ, United Kingdom

Tài liệu tham khảo

Halliwell, 1999 Melov, 2000, Extension of life-span with superoxide dismutase/catalase mimetics, Science, 289, 1567, 10.1126/science.289.5484.1567 Keaney, 2003, No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8, Free Radic. Biol. Med., 34, 277, 10.1016/S0891-5849(02)01290-X Bayne, 2002, Effects of superoxide dismutase/catalase mimetics on life span and oxidative stress resistance in the housefly, Musca domestica, Free Radic. Biol. Med., 32, 1229, 10.1016/S0891-5849(02)00849-3 Melov, 2001, Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics, J. Neurosci., 21, 8348, 10.1523/JNEUROSCI.21-21-08348.2001 Zhang, 1998, Generation of nitric oxide by a nitrite reductase activity of xanthine oxidase, Biochem. Biophys. Res. Commun., 249, 767, 10.1006/bbrc.1998.9226 Zhang, 1999, Excess nitric oxide in ulcerative colitis may be generated by nitric oxide synthase independent pathways, Gut, 44, 441, 10.1136/gut.44.3.439c Naughton, D.P., Zhang, Z., Sumi, Y., and Imaizumi, A. February 2002. Chemical compound containing a superoxide scavenger and an organic nitrate or nitrite moiety. US Patent 6,346,634 B1. Chen, 2001, Differential cytotoxicity of Mn(II) and Mn(III), Toxicol. Appl. Pharmacol., 175, 160, 10.1006/taap.2001.9245 Malecki, 2001, Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neurons, Brain Res. Bull., 55, 225, 10.1016/S0361-9230(01)00456-7 Zhang, 2003, Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat, J. Neurochem., 84, 336, 10.1046/j.1471-4159.2003.01525.x O'Neal, 1980, The effect of metal ions on mitochondrial pyridine dinucleotide transhydrogenase, Biochim. Biophys. Acta, 589, 217, 10.1016/0005-2728(80)90039-0 Heron, 2001, Paradoxical effects of copper and manganese on brain mitochondrial function, Life Sci., 68, 1575, 10.1016/S0024-3205(01)00948-1 Naughton, 2001, EDTA bis-(ethyl phenylalaninate), Bioorg. Med. Chem. Lett., 11, 2573, 10.1016/S0960-894X(01)00496-6 Fisher, 2003, Edta bis-(methyl tyrosinate), Bioorg. Med. Chem. Lett., in press Trenam, 1992, The role of iron in an acute model of skin inflammation induced by reactive oxygen species (ROS), Br. J. Dermatol., 126, 250, 10.1111/j.1365-2133.1992.tb00654.x