Leukocytes mediate disease pathogenesis in the Ndufs4(KO) mouse model of Leigh syndrome

10.1148/rg.2020200052

10.1002/path.5641

10.1097/NEN.0000000000000195

Johnson, 2015, Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice, Front Genet, 6, 10.3389/fgene.2015.00247

10.1126/science.1244360

10.1016/j.kint.2018.08.038

10.1002/acn3.50846

10.1016/j.ymgme.2020.03.007

10.3389/fgene.2017.00221

10.1038/s41598-019-39419-4

10.1038/s42255-020-00319-x

10.1073/pnas.0808594106

10.1158/1535-7163.MCT-13-0865

10.1186/s13058-016-0697-1

10.1093/neuonc/nox181

10.1158/0008-5472.CAN-16-2534

Bornstein, 2021, Differential effects of mTOR inhibition and dietary ketosis in a mouse model of subacute necrotizing encephalomyelopathy, Neurobiol Dis, 163

10.1073/pnas.0607899103

10.1021/ml200156t

10.1186/s13023-020-1297-9

10.1158/1078-0432.CCR-12-3110

10.1080/13543776.2021.1839414

10.1172/JCI62923

10.3389/fphys.2019.01113

10.1016/j.pediatrneurol.2011.04.008

10.1016/j.ejpn.2015.05.002

10.1038/jhg.2015.57

10.5692/clinicalneurol.cn-000834

10.1016/j.braindev.2011.08.004

10.1016/j.jcma.2011.05.006

10.1016/j.mri.2019.01.010

Nafisinia, 2017, Whole exome sequencing identifies the genetic basis of late-onset Leigh syndrome in a patient with MRI but little biochemical evidence of a mitochondrial disorder, JIMD Rep, 32, 117, 10.1007/8904_2016_541

10.1016/j.redox.2013.12.026

10.1213/ANE.0000000000005430

10.1097/00000542-199902000-00031

10.1213/00000539-200009000-00042

10.1002/onco.13629

10.1182/blood-2009-06-222943

10.1186/s40425-018-0457-0

10.7554/eLife.47163

10.1073/pnas.1006214107

10.1136/jnnp.14.3.216

10.1007/s00441-007-0474-7

10.1016/j.jcpa.2014.07.003

Kaiser, 2019, Tmem119-EGFP and Tmem119-CreERT2 transgenic mice for labeling and manipulating microglia, eNeuro, 6, ENEURO.0448, 10.1523/ENEURO.0448-18.2019

10.1186/s40478-019-0850-z

Johnson, 2014, Translational medicine. A target for pharmacological intervention in an untreatable human disease, Science, 346, 10.1126/science.aaa1811

10.1093/hmg/ddx341

Civiletto, 2018, Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis, EMBO Mol Med, 10, 10.15252/emmm.201708799

10.1016/j.molmet.2018.05.002

10.18632/oncotarget.12560

10.1016/j.heliyon.2019.e01217

10.1111/cts.12501

Gopal-Srivastava, 2017, Facilitating clinical studies in rare diseases, Adv Exp Med Biol, 1031, 125, 10.1007/978-3-319-67144-4_6

10.1186/s13023-018-0936-x

10.1186/s13063-017-2287-7

10.1097/MD.0000000000018634

10.1002/jimd.12281

10.1111/cge.13713

10.1016/j.cmet.2013.07.002

10.1016/j.yjmcc.2018.08.022

Chiao, 2021, NAD+ Redox imbalance in the heart exacerbates diabetic cardiomyopathy, Circ Heart Fail, 14, 10.1161/CIRCHEARTFAILURE.120.008170

10.1001/archotol.128.4.355

10.3346/jkms.2019.34.e143

10.1159/000446586

10.1515/jpem-2020-0139

Wang, 2001, Acute necrotizing encephalopathy of childhood, Chang Gung Med J, 24, 1

10.1007/s10072-018-3541-9

Wu, 1993, Leigh disease (subacute necrotizing encephalomyelopathy): report of one case, Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi, 34, 301

10.1126/science.aad9642

10.3389/fimmu.2021.753789

10.1186/s12943-019-1087-y