Lentigo Maligna on a Difficult Location of the Face Treated with 5% Imiquimod: A Case Report of 2-Year Follow-Up

Dermatology and Therapy - Tập 12 Số 2 - Trang 599-604 - 2022
Magdalena Misiak-Gałązka1, Joanna Czuwara1, A Galazka2, Anna Czaplicka1, Lidia Rudnicka
1Department of Dermatology, Medical University of Warsaw, Warsaw, Poland
2Department of Head and Neck Cancers, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland

Tóm tắt

Từ khóa


Tài liệu tham khảo

Iznardo H, Garcia-Melendo C, Yélamos O. Lentigo maligna: clinical presentation and appropriate management. Clin Cosmet Investig Dermatol. 2020;13:837–55.

Swetter SM, Tsao H, Bichakjian CK, et al. Guidelines of care for the management of primary cutaneous melanoma. J Am Acad Dermatol. 2019;80:208–50.

Hyde MA, Hadley ML, Tristani-Firouzi P, Goldgar D, Bowen GM. A randomized trial of the off-label use of imiquimod, 5%, cream with vs without tazarotene, 0.1%, gel for the treatment of lentigo maligna, followed by conservative staged excisions. Arch Dermatol. 2012;148:592–6.

Menzies SW, Liyanarachchi S, Coates E, et al. Estimated risk of progression of lentigo maligna to lentigo maligna melanoma. Melanoma Res. 2020;30:193–7.

Lallas A, Moscarella E, Kittler H, et al. Real-world experience of off-label use of imiquimod 5% as an adjuvant therapy after surgery or as a monotherapy for lentigo maligna. Br J Dermatol. 2021;185:675–7.

Tio D, van Montfrans C, Ruijter CGH, Hoekzema R, Bekkenk MW. Effectiveness of 5% topical imiquimod for lentigo maligna treatment. Acta Derm Venereol. 2019;99:884–8.

Kirtschig G, van Meurs T, van Doorn R. Twelve-week treatment of lentigo maligna with imiquimod results in a high and sustained clearance rate. Acta Derm Venereol. 2015;95:83–5.

Mora AN, Karia PS, Nguyen BM. A quantitative systematic review of the efficacy of imiquimod monotherapy for lentigo maligna and an analysis of factors that affect tumor clearance. J Am Acad Dermatol. 2015;73:205–12.

Tio D, van der Woude J, Prinsen CAC, Jansma EP, Hoekzema R, van Montfrans C. A systematic review on the role of imiquimod in lentigo maligna and lentigo maligna melanoma: need for standardization of treatment schedule and outcome measures. J Eur Acad Dermatol Venereol. 2017;31:616–24.

Schön MP, Schön M. Imiquimod: mode of action. Br J Dermatol. 2007;157(Suppl 2):8–13.