Le diabète de type 1 diminue la réponse compensatrice après un infarctus du myocarde. Rôle de l’hypothyroïdie tissulaire et effets de l’administration d’hormones thyroïdiennes

Diez, 2009, Translational approach to myocardial remodelling, Cardiovasc. Res., 81, 409, 10.1093/cvr/cvn352 Hill, 2008, Cardiac plasticity, N. Engl. J. Med., 358, 1370, 10.1056/NEJMra072139 Swynghedauw, 1999, Molecular mechanisms of myocardial remodelling, Physiol. Rev., 79, 215, 10.1152/physrev.1999.79.1.215 Dorn, 2003, Phenotyping hypertrophy: eschew obfuscation, Circ. Res., 92, 1171, 10.1161/01.RES.0000077012.11088.BC Swynghedaw, 2006, Phenotypic plasticity of adult myocardium. Molecular mechanisms, J. Exp. Biol., 209, 2320, 10.1242/jeb.02084 Cleniewski-Bernard, 2008, Proteomic analysis of left ventricular remodeling in an experimental model of heart failure, J. Proteome Res., 7, 5004, 10.1021/pr800409u Sarwar, 2009, Genomic analysis of left ventricular remodelling, Circulation, 12, 437, 10.1161/CIRCULATIONAHA.108.797225 Burak, 2007, The role of TGF-β signaling in myocardial infarction and cardiac remodeling, Cardiovascular Res., 74, 184, 10.1016/j.cardiores.2006.10.002 Frey, 2003, Cardiac hypertrophy: the good, the bad and the ugly, Annu Rev. Physiol., 65, 45, 10.1146/annurev.physiol.65.092101.142243 Wemtzel, 2003, Extension of increased atherosclerotic wall thickness into high shear stress regions is associated with loss of compensatory remodelling, Circulation, 108, 17, 10.1161/01.CIR.0000078637.21322.D3 Savoye, 2006, Left ventricular remodelling after anterior wall acute myocardial infarction in modern clinical practice (from the Remodelage Ventriculaire [REVE] study group, Am. J. Cardiol., 98, 1144, 10.1016/j.amjcard.2006.06.011 Papadopoulos, 2007, Predictors of left ventricular remodelling after reperfused acute myocardial infarction, Am. J. Cardiol., 99, 1024, 10.1016/j.amjcard.2006.11.028 Miura, 2008, Limitation of myocardial infarct size in the clinical setting: current status and challenges in translating animal experiments into clinical therapy, Basic Res. Cardiol., 103, 501, 10.1007/s00395-008-0743-y Ishii, 2008, Pharmacological intervention for prevention of left ventricular remodeling and improving prognosis in myocardial infarction, Circulation, 118, 2710, 10.1161/CIRCULATIONAHA.107.748772 Pantos, 2007, Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats, Eur. J. Cardiothorac. Surg., 32, 333, 10.1016/j.ejcts.2007.05.004 Pantos, 2008, Long-term thyroid hormone administration re-shapes left ventricular chamber and improves cardiac function after myocardial infarction in rats, Basic Res. Cardiol., 103, 308, 10.1007/s00395-008-0697-0 Pantos, 2009, Thyroid hormone at supra-physiological dose optimizes cardiac geometry and improves cardiac function in rats with old myocardial infarction, J. Physiology Pharmacol., 60, 49 Taegtmeyer, 2004, Linking gene expression to function: metabolic flexibility in normal and diseased heart, Ann. N.Y. Acad. Sci., 1015, 1, 10.1196/annals.1302.017 Stone, 1989, The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis. The MILIS Study Group, J. Am. Coll. Cardiol., 14, 49, 10.1016/0735-1097(89)90053-3 Abbott, 1988, The impact of diabetes on survival following myocardial infarction in men vs women, The Framingham study J.A.M.A., 260, 3456 Poornima, 2006, Diabetic Cardiomyopathy. The search of a unifying hypothesis, Circ. Res., 98, 596, 10.1161/01.RES.0000207406.94146.c2 Boudin, 2007, Diabetic cardiomyopathy revisited, Circulation, 115, 3213, 10.1161/CIRCULATIONAHA.106.679597 Landau, 2008, Early blood pressure-independent cardiac changes in diabetic rats, J. Endocrinol., 197, 75, 10.1677/JOE-08-0040 Van Linthout, 2008, Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy, Basic Res. Cardiol., 103, 319, 10.1007/s00395-008-0715-2 Pantos, 2007, Time-dependent changes in the expression of thyroid hormone receptor (alpha)1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling, Eur. J. Endocrinol., 156, 415, 10.1530/EJE-06-0707 Pantos, 2005, Thyroid hormone receptors alpha 1 and beta 1 are downregulated in the post-infarcted rat heart: consequences on the response to ischaemia-reperfusion. Basic Res, Cardiol., 100, 422 Martin, 2009, Effect of atorvastatin on cardiac remodelling and mortality in rats following hyperglycemia and myocardial infarction Sena, 2009, Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction, J. Mol. Cell. Cardiol., 46, 910, 10.1016/j.yjmcc.2009.02.014 Pantos, 2008, Thyroid hormone and “ cardiac metamorphosis “: Potential therapeutic implications, Pharmacol. Ther., 118, 277, 10.1016/j.pharmthera.2008.02.011 Komuro, 1996, Mechanical stretch activates the stress-activated protein kinases in cardiac myocytes, Faseb. J., 10, 631, 10.1096/fasebj.10.5.8621062 Kumphune, 2010, A chemical genetic approach reveals p38 alpha MAPK activation by diphosphorylation aggravates myocardial infarction and is prevented by the direct binding of SB203580, J. Biol. Chem., 285, 2968, 10.1074/jbc.M109.079228 Kompa, 2008, Long-term but not short-term p38 mitogen-activated protein kinase inhibition improves cardiac function and reduces cardiac remodeling post —myocardial infarction, J. Pharmacol. Exp. Ther., 325, 741, 10.1124/jpet.107.133546 Naito, 2003, Different influences of hyperglucemic duration on phosphorylated extracellular signal-regulated Kinase 1/2 in rat heart, Exp. Mol. Pathol., 74, 23, 10.1016/S0014-4800(03)80005-9 Mugoz, 2009, The transcriptum factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem. Biophysic. Res, Comm., 388, 155 Kotlyar, 2001, Insulin-like growth factor I and II preserve myocardial structure in post infarct swine, Heart, 86, 693, 10.1136/heart.86.6.693 Pantos, 2010, Rebuilding the post-infarcted myocardium by activating ‘physiologic’ hypertrophic signaling pathways: the thyroid hormone paradigm. Heart. Fail, Rev., 15, 143 Pantos C., Mourouzis I., Cokkinos D.V. — Thyroid hormone as a therapeutic option for treating ischaemic heart disease: From early reperfusion to late remodelling. Vascul. Pharmacol. (in press). Cokkinos, 2009, Les hormones thyroïdiennes, action sur le myocarde, Bull. Acad. Natle Méd., 193, 327 Tang, 2005, Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles and severe systolic dysfunction, Circulation, 112, 3122, 10.1161/CIRCULATIONAHA.105.572883