Layer‐by‐layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textiles

Polymers for Advanced Technologies - Tập 24 Số 11 - Trang 1005-1010 - 2013
Ana P. Gomes1, João F. Mano2,3, João A. Queiroz4, Isabel C. Gouveia1
1R&D Unit of Textile and Paper Materials, Faculty of Engineering University of Beira Interior 6201‐001 Covilhã Portugal
23B's Research Group ‐ Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine AvePark, 4806‐909 Taipas Guimarães Portugal
3ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal
4Health Sciences Research Centre University of Beira Interior 6201‐001 Covilhã Portugal

Tóm tắt

In recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health‐care field. Copyright © 2013 John Wiley & Sons, Ltd.

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Tài liệu tham khảo

10.1007/s12221-009-0161-2

10.1021/bm070014y

10.1002/mabi.200800336

10.4014/jmb.0904.04038

10.1016/j.jconrel.2006.04.017

10.4314/tjpr.v8i1.14712

10.1007/s12221-011-0015-6

10.1081/MC-120020160

10.1016/S0142-9612(00)00201-5

10.1016/0040-6090(92)90417-A

10.1021/la00026a020

10.1007/s10924-012-0507-5

10.1063/1.1375156

A.Nabok Organic and inorganic nanostructures. Microelectromechanical systems series.2005 Boston: Artech House. xi 268.

10.1088/0957-4484/16/7/017

10.1016/j.colsurfa.2006.04.012

10.3139/146.110726

R. A.Jewell B. WA (US); Joseph L. Komen Bothell WA (US); Bing Su Federal Way WA (US); s. Ananda Weerawarna Seattle WA (US); Yong Li Tacoma WA (US).Method of making carboxylated cellulose fibers and products of the method.Patent Nº US 6 524 348 B1

10.1016/j.carbpol.2006.01.034

10.1016/j.carbpol.2007.04.014

10.1016/j.carbpol.2007.07.019

10.1016/j.polymer.2009.04.046

10.1016/S0144-8617(01)00212-0

10.1007/s12221-010-0357-5

JIS L 1902 Testing for antibacterial activity and efficacy on textile products 2002: Japanese Industrial Standard.

10.1086/381972

10.1016/S0168-1605(01)00717-6

10.1007/s10570-012-9713-5

10.1016/j.ijbiomac.2009.07.006

10.1016/j.carbpol.2003.07.009

10.1016/j.carres.2004.09.007

10.1007/s00289-005-0414-1

10.1002/app.25508

10.1016/j.biortech.2007.06.044

10.1016/j.jcis.2012.02.039

10.1007/s10517-005-0489-6

10.1016/j.dyepig.2004.09.005

10.1016/j.carbpol.2012.09.034

10.1016/j.jphotobiol.2011.06.009

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Polymers for Advanced Technologies

Tập 24 Số 11

1005-1010

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