Latex-fruit syndrome

Poley GE, Slater JE: Latex allergy. J Allergy Clin Immunol 2000, 105:1054–1062. A recent review on latex allergy, dealing with several aspects that cover from definition to treatment.

Charous BL, Blanco C, Tarlo S, et al.: Natural rubber latex allergy after 12 years: recommendations and perspectives. J Allergy Clin Immunol 2002, 109:31–34. A brief update on the current status of latex allergy and its future perspectives. Some practical recommendations are made.

Kurup VP, Fink JN: The spectrum of immunologic sensitization in latex allergy. Allergy 2001, 56:2–12.

Alenius H, Kalkkinen N, Reunala T, et al.: The main IgE-binding epitope of a major latex allergen, prohevein, is present in its N-terminal 43-amino acid fragment, hevein. J Immunol 1996, 156:618–625.

Fritsch R, Ebner C, Kraft D: Allergenic crossreactivities pollen and vegetable foods. Clin Rev Allergy Immunol 1997, 15:397–404.

Vieths S, Scheurer S, Ballmer-Weber B: Current understanding of cross-reactivity of food allergens and pollen. Ann N Y Acad Sci 2002, 964:47–68.

BreitenederH, Ebner C: Molecular and biochemical classification of plant-derived food allergens. J Allergy Clin Immunol 2000, 106:27–36. Modern classification of plant-derived food allergens, including families of pathogenesis related proteins, profilins, enzymes and storage proteins. Specific comments on PR-3 type proteins or basic chitinases are included.

HanninenAR, Mikkola JH, Kalkkinen N, et al.: Increased allergen production in turnip (Brassica rapa) by treatments activating defense mechanisms. J Allergy Clin Immunol 1999, 104:194–201. Using a plant model, an increase in prohevein-like allergen content after treatments activating plant defense mechanisms is demonstrated. This could explain, at least in part, the increase in prevalence of latex-fruit allergy.

Sanchez-Monge R, Lombardero M, Garcia-Selles FJ, et al.: Lipidtransfer proteins are relevant allergens in fruit allergy. J Allergy Clin Immunol 1999, 103:514–519.

Valenta R, Duchene M, Ebner C, et al.: Profilins constitute a novel family of functional plant panallergens. J Exp Med 1992, 175:377–385.

M’Raihi L, Charpin D, Pons A, et al.: Cross-reactivity between latex and banana. J Allergy Clin Immunol 1991, 87:129–130.

Lavaud F, Cossart C, Reiter V, et al.: Latex allergy in patient with allergy to fruit (letter). Lancet 1992, 339:492–493.

Ceuppens JL, Van Durme P, Dooms-Goossens A: Latex allergy in patient with allergy to fruit (letter). Lancet 1992, 339:493.

de CorresLF, Moneo I, Muñoz D, et al.: Sensitization from chestnuts and bananas in patients with urticaria and anaphylaxis from contact with latex. Ann Allergy 1993, 70:35–39.

Rodríguez M, Vega F, García MT, et al.: Hypersensitivity to latex, chestnut, and banana. Ann Allergy 1993, 70:31–34.

Añíbarro B, García-Ara MC, Pascual C: Associated sensitization to latex and chestnut. Allergy 1993, 70:130–131.

Blanco C, Carrillo T, Castillo R, et al.: Latex allergy: clinical features and cross-reactivity with fruits. Ann Allergy 1994, 73:309–314.

Mäkinen-Kiljunen S: Banana allergy in patients with immediate-type hypersensitivity to natural rubber latex: characterization of cross-reacting antibodies and allergens. J Allergy Clin Immunol 1994, 93:990–996.

Lavaud F, Prevost A, Cossart C, et al.: Allergy to latex, avocado pear, and banana: evidence for a 30 kD antigen in immunoblotting. J Allergy Clin Immunol 1995, 95:557–564.

Delbourg MF, Guilloux L, Moneret-Vautrin DA, Ville G: Hypersensitivity to banana in latex-allergic patients: identification of two major banana allergens of 33 and 37 kD. Ann Allergy Asthma Immunol 1996, 76:321–326.

Beezhold DH, Sussman GL, Liss GM, Chang NS: Latex allergy can induce clinical reactions to specific foods. Clin Exp Allergy 1996, 26:416–422.

Brehler R, Theissen U, Mohr C, Luger T: "Latex-fruit syndrome": frequency of cross-reacting IgE antibodies. Allergy 1997, 52:404–410.

Kim KT, Hussain H: Prevalence of food allergy in 137 patients. Allergy Asthma Proc 1999, 20:95–97.

Blanco C, Carrillo T, Castillo R, et al.: Avocado hypersensitivity. Allergy 1994, 49:454–459.

Carrillo T, Blanco C, Quiralte J, et al.: Prevalence of latex allergy among greenhouse workers. J Allergy Clin Immunol 1995, 96:699–701.

García JC, Moyano JC, Alvarez M, Bellido J: Latex allergy in fruit-allergic patients. Allergy 1998, 53:532–536.

Díez-Gómez ML, Quirce S, Cuevas M, et al.: Fruit-pollen-latex cross-reactivity: implication of profilin (Bet v 2). Allergy 1999, 54:951–961.

Levy DA, Mounedji N, Noirot C, Leynadier F: Allergic sensitization and clinical reactions to latex, food and pollen in adult patients. Clin Exp Allergy 2000, 30:270–275. A very interesting clinical study that tries to discern the relationship among latex, pollen, and food allergies in adult patients.

SalcedoG, Diaz-Perales A, Sánchez-Monge R: The role of plant panallergens in sensitization to natural rubber latex. Curr Opin Allergy Clin Immunol 2001, 1:177–183. An excellent review article on the plant panallergens implicated in latex-fruit cross-reactivity.

Sowka S, Hafner C, Radauer C, et al.: Molecular and immunologic characterization of new isoforms of the hevea brasiliensis latex allergen Hev b 7: evidence of no cross-reactivity between Hev b 7 isoforms and potato patatin and proteins from avocado and banana. J Allergy Clin Immunol 1999, 104:1302–1310.

Seppala U, Palosuo T, Seppala U, et al.: IgE reactivity to patatin-like latex allergen, Hev b 7, and to patatin of potato tuber, Sol t 1, in adults and children allergic to natural rubber latex. Allergy 2000, 55:266–273.

Akasawa A, Hsieh LS, Martin BM, et al.: A novel acidic allergen, Hev b 5, in latex: purification, cloning and characterization. J Biol Chem 1996, 271:25389–25393.

Slater JE, Vedvick T, Arthur-Smith A, et al.: Identification, cloning, and sequence of a major latex allergen (Hev b 5) from natural rubber latex (Hevea brasiliensis). J Biol Chem 1996, 271:25394–25399.

Beezhold DH, Hickey VL, Slater JE, Sussman GL: Human IgEbinding epitopes of the latex allergen Hev b 5. J Allergy Clin Immunol 1999, 103:1166–1172.

Ganglberger E, Radauer C, Wagner S, et al.: Hev b 8, the Hevea brasiliensis profilin, is a cross-reactive allergen of latex, plant foods and pollen. Int Arch Allergy Immunol 2001, 125:216–227.

Reindl J, Rihs HP, Scheurer S, et al.: IgE reactivity to profilin in pollen-sensitized subjects with adverse reactions to banana and pineapple. Int Arch Allergy Immunol 2002, 128:105–114.

Wagner S, Breiteneder H, Simon-Nobbe B, et al.: Hev b 9, an enolase and a new cross-reactive allergen from hevea latex and molds: purification, characterization, cloning and expression. Eur J Biochem 2000, 267:7006–7014.

Wagner S, Sowka S, Mayer C, et al.: Identification of a Hevea brasiliensis latex manganese superoxide dismutase (Hev b 10) as a cross-reactive allergen. Int Arch Allergy Immunol 2001, 125:120–127.

Diaz-Perales A, Collada C, Blanco C, et al.: Class I chitinases with hevein-like domain, but not class II enzymes, are relevant chestnut and avocado allergens. J Allergy Clin Immunol 1998, 102:127–133.

Sowka S, Hsieh LS, Krebitz M, et al.: Identification and cloning of Prs a 1, a 32 kDa endochitinase and major allergen of avocado, and its expression in the yeast Pichia pastoris. J Biol Chem 1998, 273:28091–28097.

Chen Z, Posch A, Cremer R, et al.: Identification of hevein (Hev b 6.02) in Hevea latex as a major cross-reacting allergen with avocado fruit in patients with latex allergy. J Allergy Clin Immunol 1998, 102:476–481.

Blanco C, Diaz-Perales A, Collada C, et al.: Class I chitinases are major panallergens responsible for the latex-fruit syndrome. J Allergy Clin Immunol 1999, 103:507–513. A study using purified chitinases from chestnut and avocado, demonstrating that they are major allergens implicated in latex-fruit cross-reactivity.

Sanchez-Monge R, Blanco C, Díaz-Perales A, et al.: Isolation and characterization of relevant banana allergens: identification as fruit class I chitinases. Clin Exp Allergy 1999, 29:673–680. Identification of class I chitinases as major banana allergens crossreacting with latex.

Mikkola JH, Alenius H, Kalkkinen N, et al.: Hevein-like protein domains as a possible cause for allergen cross-reactivity between latex and banana. J Allergy Clin Immunol 1998, 102:1005–1012.

Diaz-Perales A, Collada C, Blanco C, et al.: Cross-reactions in the latex-fruit syndrome: a relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999, 104:681–687.

Sanchez-Monge R, Blanco C, Díaz-Perales A, et al.: Class I chitinases, the panallergens responsible for the latex-fruit syndrome, are induced by ethylene treatment and inactivated by heating. J Allergy Clin Immunol 2000, 106:190–195. An experimental model to demonstrate different expression of chitinases depending on plant growing — or food processing — conditions. Its clinical implications should be carefully considered.

Diaz-Perales A, Sánchez-Monge R, Blanco C, et al.: What is the role of the hevein-like domain of fruit class I chitinases in their allergenic capacity?. Clin Exp Allergy 2002, 32:448–454.

O’Riordain G, Radauer C, Hoffman-Sommergruber K, et al.: Molecular characterisation and cloning of the Hevea brasiliensis allergen Hev b 11, a class I chitinase. Clin Exp Allergy 2002, 32:455–462.

Chen Z, Duser M, Flagge A, et al.: Identification and characterization of cross-reactive natural rubber latex and Ficus benjamina allergens. Int Arch Allergy Immunol 2000, 123:291–298.

Sicherer SH: Clinical implications of cross-reactive food allergens. J Allergy Clin Immunol 2001, 108:881–890. A comprehensive review focused on clinical aspects of cross-reacting food allergens, with special mention of the latex-food allergy.