Laryngeal dysfunction in Amyotrophic Lateral Sclerosis: a review and case report

BMC Ear, Nose and Throat Disorders - Tập 1 - Trang 1-5 - 2001
Christopher R Watts1, Martine Vanryckeghem2
1Department of Speech Pathology & Audiology, University of South Alabama, Mobile, AL, USA
2Department of Communicative Disorders, University of Central Florida, Orlando, USA

Tóm tắt

Laryngeal dysfunction can be a salient feature in the clinical symptomatology of speakers diagnosed with Amyotrophic Lateral Sclerosis (ALS). In addition to dysphonia, swallowing function is also disrupted. This paper reviews what is known about laryngeal dysfunction resulting from ALS. Presented is a case report of a female, diagnosed with ALS, whose initial symptoms were caused by laryngeal bulbar involvement that was characterized by dysphonia and dysphagia. In bulbar forms of ALS, voice and/or swallowing difficulties are often the initial signs of disease. Careful examination of the muscles innervated by bulbar nerves, and tracking the rate of progressive deficit in the affected muscles, will help to solidify an accurate diagnosis. With therapy, the ability to swallow safely may still be maintained even when voice and articulation abilities are such that oral communication is inefficient.

Tài liệu tham khảo

Carrow E, Rivera V, Maulding M, Shamblin L: Deviant speech characteristics in motor neuron disease. Archives of Otolaryngology,. 1974, 100: 212-218. Lewis L, Shneider N: Medical Progress: Amyotrophic lateral sclerosis. The New England Journal of Medicine,. 2001, 344: 1688-1700. 10.1056/NEJM200105313442207. Tandan R, Bradley D: Amyotrophic lateral sclerosis: Part 1. clinical features, pathology, and ethical issues in management. Annals of Neurology,. 1985, 18: 271-280. Yorkston K, Beukelman D, Strand E, Bell K: Management of Motor Speech Disorders in Children and Adults. Austin: Pro-Ed. 1999 Duffy J: Motor Speech Disorders: Substrates, Differential Diagnosis, and Management. Mosby, St. Louis. 1995 Kent R, Kent J, Duffy J, Weismer G: The dysarthrias: speech-voice profiles, related dysfunctions, and neuropathology. Journal of Medical Speech-Language Pathology,. 1998, 6: 165-211. Roth C, Glaze L, Goding G, David W: Spasmodic dysphonia symptoms as initial presentation of amyotrophic lateral sclerosis. Journal of Voice,. 1996, 10: 362-367. Hillel A, Dray T, Miller R, Yorkston K, Konikow N, Strande E, Browne J: Presentation of ALS to the otolaryngologist/head and neck surgeon: getting to the neurologist. Neurology,. 1995, 53: S22-S25. Mathieson L: The Voice and its Disorders. Whurr, London. 2001 Strand E, Buder E, Yorkston K, Ramig L: Differential phonatory characteristics of four women with amyotrophic lateral sclerosis. Journal of Voice,. 1994, 8: 327-339. Silbergleit A, Johnson A, Jacobson B: Acoustic analysis of voice in individuals with amyotrophic lateral sclerosis and perceptually normal vocal quality. Journal of Voice,. 1997, 11: 222-231. Klasner E, Yorkston K, Strand E: Patterns of perceptual features in speakers with ALS: a preliminary study of prominence and intelligibility considerations. Journal of Medical Speech-Language Pathology,. 1999, 7: 117-125. Aronson A: Clinical Voice Disorders. New York, Thieme. 1990 Janzen V, Rae R, Hudson A: Otolaryngologic manifestations of amyotrophic lateral sclerosis. Journal of Otolaryngology,. 1988, 17: 201-222. Hillel A, Miller R: Bulbar amyotrophic lateral sclerosis: patterns of progression and clinical management. Head and Neck,. 1989, 11: 51-59. Quinn N, Wenning G: Multiple system atrophy. Current Opinion in Neurology,. 1995, 8: 323-326. Kluin K, Gilman S, Lohman M, Junck L: Perceptual analysis of speech disorders in progressive supranuclear palsy. Neurology,. 1996, 53: 545-548. Dworkin J, Hartman D: Progressive speech deterioration and dysphagia in amyotrophic lateral sclerosis: case report. Archives of Physical and Medical Rehabilitation,. 1979, 60: 423-425. Strand E, Miller R, Yorkston K, Hillel A: Management of oral-pharyngeal dysphagia symptoms in amyotrophic lateral sclerosis. Dysphagia,. 1996, 11: 129-139. The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1472-6815/1/1/prepub