Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation

Journal of Proteomics - Tập 75 - Trang 2384-2395 - 2012
Omid Azimzadeh1, Harry Scherthan2, Ramesh Yentrapalli1,3, Zarko Barjaktarovic1, Marius Ueffing4,5, Marcus Conrad6, Frauke Neff7, Julia Calzada-Wack7, Michaela Aubele7, Christian Buske8, Michael J. Atkinson1,9, Stefanie M. Hauck4, Soile Tapio1
1Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Radiation Biology, Neuherberg, Germany
2Bundeswehr Institute of Radiobiology Affiliated to the University of Ulm, Munich, Germany
3Centre for Radiation Protection Research, Department of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden
4Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit Protein Science, Neuherberg, Germany
5Centre of Ophthalmology, University Medical Centre, Tübingen, Germany
6DZNE, German Center for Neurodegenerative Diseases and Helmholtz Zentrum München, Institute of Developmental Genetics, Neuherberg, Germany
7Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Pathology, Neuherberg, Germany
8Institute of Experimental Cancer Research, University Hospital Ulm, Ulm, Germany
9Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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