LSD, 5-HT (serotonin), and the evolution of a behavioral assay

Appel, 1982, Analyzing mechanism(s) of hallucinogenic drug action with drug discrimination procedures, Neurosci Biobehav Rev, 6, 529, 10.1016/0149-7634(82)90036-7 Appel, 1999, Increasing the selectivity of drug discrimination procedures, Pharmacol Biochem Behav, 64, 353, 10.1016/S0091-3057(99)00089-1 Colpaert, 1982, Factors regulating drug cue sensitivity: the effects of dose ratio and absolute dose level in the case of fentanyl dose-dose discrimination, Arch Internat Pharmacodyn Ther, 258, 283 Fiorella, 1995, Role of 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs II: reassessment of LSD false positives, Psychopharmacol, 121, 357, 10.1007/BF02246075 Colpaert, 1982, A drug discrimination analysis of lysergic acid diethylamide LSD: in vivo agonist and antagonist effects of purported serotonin antagonists and of pirenperone, an LSD-antagonist, J Pharmacol Exp Ther, 221, 206 Colpaert, 1985, Behavioral and 5-HT antagonist effects of ritanserin: a pure and selective antagonist of LSD discrimination in rat, Psychopharmacol, 86, 45, 10.1007/BF00431683 West, 1995, Effects of 5-HT2 and DA antagonism on the stimulus properties of LSD, Soc Neurosci Abstr, 21, 1130 Cunningham, 1987, Neuropharmacological reassessment of the discriminative stimulus properties of dlysergic acid diethylamide LSD, Psychopharmacol, 91, 67, 10.1007/BF00690929 Burris, 1991, (+) Lysergic Acid Diethylamide, but not its non-hallucinogenic congeners, is a potent serotonin 5-HT1C receptor agonist, J Pharmacol Exp Ther, 258, 891 Appel, 1991, Use of drug discrimination in drug abuse research, 16, 369 White, 1982, Training dose as a factor in LSD-saline discrimination, Psychopharmacol, 76, 20, 10.1007/BF00430748 White, 1982, Lysergic acid diethylamide (LSD) and lisuride: differentiation of their neuropharmacological actions, Science, 216, 535, 10.1126/science.7071600 White, 1982, The role of dopamine and serotonin in the discriminative stimulus effects of lisuride, J Pharmacol Exp Ther, 221, 421 Järbe, 1982, 327 Swedberg, 1985, Drug discrimination procedures: roles of relative stimulus control in two-drug cases, Psychopharmacol, 86, 444, 10.1007/BF00427906 Callahan, 1990, Differentiation between the stimulus effects of LSD and lisuride using a three choice drug discrimination procedure, Psychopharmacology, 100, 131, 10.1007/BF02245782 Swedberg, 1986, Drug discrimination procedures: differential characteristics of the drug A vs. drug B and the drug A vs. drug B vs. no drug cases, Psychopharmacol, 90, 341, 10.1007/BF00179188 White, 1986, Comparative effects of LSD and lisuride, clues to specific hallucinogenic drug actions, Pharmacol Biochem Behav, 24, 365, 10.1016/0091-3057(86)90367-9 Overton, 1982, Multiple drug training as a method for increasing the specificity of the drug discrimination procedure, J Pharmacol Exp Ther, 221, 166 Palacios, 1990, Distribution of serotonin receptors, Ann NY Acad Science, 600, 36, 10.1111/j.1749-6632.1990.tb16871.x Deutch, 1992, Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell, Neurosci, 46, 49, 10.1016/0306-4522(92)90007-O Haigler, 1973, direct and indirect effects on serotonin-containing neurons in brain, Eur J Pharmacol, 21, 53, 10.1016/0014-2999(73)90206-9 Hirschhorn, 1975, Discriminative control of behavior by electrical stimulation of the dorsal raphe nucleus: generalization to lysergic acid diethylamide (LSD), Brain Res, 86, 134, 10.1016/0006-8993(75)90645-9 Minnema, 1980, LSD as a discriminative stimulus: role of dorsal raphe nucleus, Subst Alcohol Actions Misuse, 1, 29 Waeber, 1994, Binding sites for 5-hydroxytryptamine-2 receptor agonists are predominantly located in striosomes in the human basal ganglia, Brain Res Mol Brain Res, 24, 199, 10.1016/0169-328X(94)90133-3 Wise, 1987, A psychomotor stimulant theory of addiction, Psychol Rev, 94, 469, 10.1037/0033-295X.94.4.469 Nielsen, 1986, Cueing effects of amphetamine and LSD: elicitation by direct microinjection of the drugs into the nucleus accumbens, Eur J Pharmacol, 125, 85, 10.1016/0014-2999(86)90086-5 Glennon, 1984, Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents, Life Sci, 35, 2505, 10.1016/0024-3205(84)90436-3 Whitaker-Azmitia, 1999, The discovery of serotonin and its role in neuroscience, Neuropsychopharmacol, 21, 2S, 10.1016/S0893-133X(99)00031-7 Jacobs, 1999, Activity of serotonergic neurons in behaving animals, Neuropsychopharmacol, 21, 9S, 10.1016/S0893-133X(99)00012-3