LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

Ai, 2000, Wnt-1 regulation of connexin43 in cardiac myocytes, J. Clin. Invest., 105, 161, 10.1172/JCI7798

Aubin, 1998, Advances in the osteoblast lineage, Biochem. Cell Biol., 76, 899, 10.1139/o99-005

Bafico, 2001, Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow, Nat. Cell Biol., 3, 683, 10.1038/35083081

Bohme, 1995, Primary structure of the long and short splice variants of mouse collagen XII and their tissue-specific expression during embryonic development, Dev. Dyn., 204, 432, 10.1002/aja.1002040409

Brown, 1986, A receptor-mediated pathway for cholesterol homeostasis, Science, 232, 34, 10.1126/science.3513311

Chen, 1999, Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human, Genomics, 55, 314, 10.1006/geno.1998.5688

Dong, 1998, Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity, Biochem. Biophys. Res. Commun., 251, 784, 10.1006/bbrc.1998.9545

Fedde, 1999, Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia, J. Bone Miner. Res., 14, 2015, 10.1359/jbmr.1999.14.12.2015

Figueroa, 2000, Expression of the type I diabetes-associated gene LRP5 in macrophages, vitamin A system cells, and the Islets of Langerhans suggests multiple potential roles in diabetes, J. Histochem. Cytochem., 48, 1357, 10.1177/002215540004801006

Gliemann, 1998, Receptors of the low density lipoprotein (LDL) receptor family in man. Multiple functions of the large family members via interaction with complex ligands, Biol. Chem., 379, 951

Globus, 1998, Fibronectin is a survival factor for differentiated osteoblasts, J. Cell Sci., 111, 1385, 10.1242/jcs.111.10.1385

Glorieux, 2000, Normative data for iliac bone histomorphometry in growing children, Bone, 26, 103, 10.1016/S8756-3282(99)00257-4

Gong, 1996, Osteoporosis-pseudoglioma syndrome, a disorder affecting skeletal strength and vision, is assigned to chromosome region 11q12–13, Am. J. Hum. Genet., 59, 146

Gradl, 1999, The Wnt/Wg signal transducer beta-catenin controls fibronectin expression, Mol. Cell. Biol., 19, 5576, 10.1128/MCB.19.8.5576

Haertel-Wiesmann, 2000, Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells, J. Biol. Chem., 275, 32046, 10.1074/jbc.M000074200

Hey, 1998, Cloning of a novel member of the low-density lipoprotein receptor family, Gene, 216, 103, 10.1016/S0378-1119(98)00311-4

Horiuchi, 1999, Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta, J. Bone Miner. Res., 14, 1239, 10.1359/jbmr.1999.14.7.1239

Huang, 1997, Mouse clavicular development, Dev. Dyn., 210, 33, 10.1002/(SICI)1097-0177(199709)210:1<33::AID-AJA4>3.0.CO;2-2

Hussain, 1999, The mammalian low-density lipoprotein receptor family, Annu. Rev. Nutr., 19, 141, 10.1146/annurev.nutr.19.1.141

Ito, 1999, Regression of the hyaloid vessels and pupillary membrane of the mouse, Anat. Embryol., 200, 403, 10.1007/s004290050289

Jochum, 2000, Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1, Nat. Med., 6, 980, 10.1038/79676

Johnson, 1997, Linkage of a gene causing high bone mass to human chromosome 11 (11q12–13), Am. J. Hum. Genet., 60, 1326, 10.1086/515470

Katagiri, 1994, Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage, J. Cell Biol., 127, 1755, 10.1083/jcb.127.6.1755

Kim, 1998, A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E, J. Biochem., 124, 1072, 10.1093/oxfordjournals.jbchem.a022223

Ko, 1985, Hyaloid vascular pattern in the human fetus, J. Pediatr. Ophthalmol. Strabismus, 22, 188, 10.3928/0191-3913-19850901-07

Koller, 1998, Linkage of a QTL contributing to normal variation in bone mineral density to chromosome 11q12–13, J. Bone Miner. Res., 13, 1903, 10.1359/jbmr.1998.13.12.1903

Lang, 1993, Macrophages are required for cell death and tissue remodeling in the developing mouse eye, Cell, 74, 453, 10.1016/0092-8674(93)80047-I

Li, 1992, The autosomal dominant familial exudative vitreoretinopathy locus maps on 11q and is closely linked to D11S533, Am. J. Hum. Genet., 51, 749

Lu, 1996, Volumetric bone mineral density in normal subjects, aged 5–27 years, J. Clin. Endocrinol. Metab., 81, 1586

Mann, 1999, Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas, Proc. Natl. Acad. Sci. USA, 96, 1603, 10.1073/pnas.96.4.1603

Mao, 2001, Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway, Mol. Cell, 7, 801, 10.1016/S1097-2765(01)00224-6

Morin, 1997, Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC, Science, 275, 1787, 10.1126/science.275.5307.1787

Mornet, 2000, Hypophosphatasia, Hum. Mutat., 15, 309, 10.1002/(SICI)1098-1004(200004)15:4<309::AID-HUMU2>3.0.CO;2-C

Moursi, 1996, Fibronectin regulates calvarial osteoblast differentiation, J. Cell Sci., 109, 1369, 10.1242/jcs.109.6.1369

2001, Osteoporosis prevention, diagnosis, and therapy, JAMA, 285, 785, 10.1001/jama.285.6.785

Parfitt, 1987, Bone histomorphometry, J. Bone Miner. Res., 2, 595, 10.1002/jbmr.5650020617

Pinson, 2000, An LDL-receptor-related protein mediates Wnt signalling in mice, Nature, 407, 535, 10.1038/35035124

Riggs, 1986, Involutional osteoporosis, N. Engl. J. Med., 314, 1676, 10.1056/NEJM198606263142605

Roodman, 1996, Advances in bone biology, Endocr. Rev., 17, 308

Sabatakos, 2000, Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis, Nat. Med., 6, 985, 10.1038/79683

Seeman, 1994, Reduced femoral neck bone density in the daughters of women with hip fractures, J. Bone Miner. Res., 9, 739, 10.1002/jbmr.5650090520

Semenov, 2001, Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6, Curr. Biol., 11, 951, 10.1016/S0960-9822(01)00290-1

Shibamoto, 1998, Cytoskeletal reorganization by soluble Wnt-3a protein signalling, Genes Cells, 3, 659, 10.1046/j.1365-2443.1998.00221.x

Shimizu, 1997, Transformation by Wnt family proteins correlates with regulation of beta-catenin, Cell Growth Differ., 8, 1349

Spinella-Jaegle, 2001, Sonic Hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation, J. Cell Sci., 114, 2085, 10.1242/jcs.114.11.2085

Stone, 1992, Genetic linkage of autosomal dominant neovascular inflammatory vitreoretinopathy to chromosome 11q13, Hum. Mol. Genet., 1, 685, 10.1093/hmg/1.9.685

Tamai, 2000, LDL-receptor-related proteins in Wnt signal transduction, Nature, 407, 530, 10.1038/35035117

Uusitalo, 1999, Molecular genetic studies of Wnt signaling in the mouse, Exp. Cell Res., 253, 336, 10.1006/excr.1999.4710

van de Wetering, 1997, Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF, Cell, 88, 789, 10.1016/S0092-8674(00)81925-X

Wehrli, 2000, arrow encodes an LDL-receptor-related protein essential for Wingless signalling, Nature, 407, 527, 10.1038/35035110

Wennberg, 2000, Functional characterization of osteoblasts and osteoclasts from alkaline phosphatase knockout mice, J. Bone Miner. Res., 15, 1879, 10.1359/jbmr.2000.15.10.1879

Yamaguchi, 1996, Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3–G2/PA6, Biochem. Biophys. Res. Commun., 220, 366, 10.1006/bbrc.1996.0411

Zhu, 2000, The human hyaloid system, Exp. Eye Res., 70, 767, 10.1006/exer.2000.0844