Kruppel-like Factors (KLFs) in muscle biology

Journal of Molecular and Cellular Cardiology - Tập 43 - Trang 1-10 - 2007
Saptarsi M. Haldar1, Osama A. Ibrahim1, Mukesh K. Jain1
1Case Cardiovascular Research Institute, Case Western Reserve University School of Medicine and University Hospitals of Cleveland / Case Medical Center, 2103 Cornell Road, Room 4-503, Cleveland, OH 44106, USA

Tài liệu tham khảo

Jain, 2005, Anti-inflammatory effects of statins: clinical evidence and basic mechanisms, Nat. Rev., Drug Discov., 4, 977, 10.1038/nrd1901 Ventura-Clapier, 2007, Beneficial effects of endurance training on cardiac and skeletal muscle energy metabolism in heart failure, Cardiovasc. Res., 73, 10, 10.1016/j.cardiores.2006.09.003 Libera, 2004, Muscle wastage in chronic heart failure, between apoptosis, catabolism and altered anabolism: a chimaeric view of inflammation?, Curr. Opin. Clin. Nutr. Metab. Care, 7, 435, 10.1097/01.mco.0000134374.24181.5b Finck, 2006, PGC-1 coactivators: inducible regulators of energy metabolism in health and disease, J. Clin. Invest., 116, 615, 10.1172/JCI27794 McKinsey, 2005, Toward transcriptional therapies for the failing heart: chemical screens to modulate genes, J. Clin. Invest., 115, 538, 10.1172/JCI24144 Heineke, 2006, Regulation of cardiac hypertrophy by intracellular signalling pathways, Nat. Rev., Mol. Cell Biol., 7, 589, 10.1038/nrm1983 Gerthoffer, 2007, Mechanisms of vascular smooth muscle cell migration, Circ. Res., 100, 607, 10.1161/01.RES.0000258492.96097.47 Nuez, 1995, Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene, Nature, 375, 316, 10.1038/375316a0 Akazawa, 2003, Roles of cardiac transcription factors in cardiac hypertrophy, Circ. Res., 92, 1079, 10.1161/01.RES.0000072977.86706.23 Adhikari, 2006, Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury, Curr. Atheroscler. Rep., 8, 252, 10.1007/s11883-006-0081-1 Epstein, 2005, Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease, Circulation, 112, 592, 10.1161/CIRCULATIONAHA.104.479857 Perry, 2002, Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements, Eur. J. Biochem., 269, 3607, 10.1046/j.1432-1033.2002.02999.x Oettgen, 2006, Regulation of vascular inflammation and remodeling by ETS factors, Circ. Res., 99, 1159, 10.1161/01.RES.0000251056.85990.db Puigserver, 2003, Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator, Endocr. Rev., 24, 78, 10.1210/er.2002-0012 Wei, 2006, Emerging role of KLF4 in human gastrointestinal cancer, Carcinogenesis, 27, 23, 10.1093/carcin/bgi243 Feinberg, 2004, An emerging role for Kruppel-like factors in vascular biology, Trends Cardiovasc. Med., 14, 241, 10.1016/j.tcm.2004.06.005 Suzuki, 2005, Vascular implications of the Kruppel-like family of transcription factors, Arterioscler. Thromb. Vasc. Biol., 25, 1135, 10.1161/01.ATV.0000165656.65359.23 Turner, 1999, Basic Kruppel-like factor functions within a network of interacting haematopoietic transcription factors, Int. J. Biochem. Cell Biol., 31, 1169, 10.1016/S1357-2725(99)00067-9 Bieker, 1996, Isolation, genomic structure, and expression of human erythroid Kruppel-like factor (EKLF), DNA Cell Biol., 15, 347, 10.1089/dna.1996.15.347 Dang, 2002, Opposing effects of Kruppel-like factor 4 (gut-enriched Kruppel-like factor) and Kruppel-like factor 5 (intestinal-enriched Kruppel-like factor) on the promoter of the Kruppel-like factor 4 gene, Nucleic Acids Res., 30, 2736, 10.1093/nar/gkf400 Nusslein-Volhard, 1980, Mutations affecting segment number and polarity in Drosophila, Nature, 287, 795, 10.1038/287795a0 Jackle, 1985, Molecular analysis of Kruppel, a segmentation gene of Drosophila melanogaster, Cold Spring Harb Symp. Quant Biol., 50, 465, 10.1101/SQB.1985.050.01.058 Zuo, 1991, Activation and repression of transcription by the gap proteins hunchback and Kruppel in cultured Drosophila cells, Genes Dev., 5, 254, 10.1101/gad.5.2.254 Gloor, 1950, Arch. Julius–Klaus–Stift, VererbForsch, 25, 38 Miller, 1993, A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins, Mol. Cell. Biol., 13, 2776, 10.1128/MCB.13.5.2776 Perkins, 1995, Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF, Nature, 375, 318, 10.1038/375318a0 Fisch, 2007, Kruppel-like Factor 15 is a Novel Regulator of Cardiomyocyte Hypertrophy, Proc Natl Acad Sci U.S.A., 104, 7074, 10.1073/pnas.0701981104 Shindo, 2002, Kruppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling, Nat. Med., 8, 856, 10.1038/nm738 Bhattacharya, 2005, Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2, J. Biol. Chem., 280, 28848, 10.1074/jbc.C500200200 Rowland, 2005, The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene, Nat. Cell Biol., 7, 1074, 10.1038/ncb1314 SenBanerjee, 2004, KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation, J. Exp. Med., 199, 1305, 10.1084/jem.20031132 Parmar, 2006, Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2, J. Clin. Invest., 116, 49, 10.1172/JCI24787 Gray, 2007, Regulation of gluconeogenesis by Kruppel-like Factor 15, Cell Metab., 5, 305, 10.1016/j.cmet.2007.03.002 Das, 2006, Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes, Proc. Natl. Acad. Sci. U. S. A., 103, 6653, 10.1073/pnas.0508235103 Feinberg, 2005, Kruppel-like factor 4 is a mediator of proinflammatory signaling in macrophages, J. Biol. Chem., 280, 38247, 10.1074/jbc.M509378200 Takahashi, 2006, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell, 126, 663, 10.1016/j.cell.2006.07.024 Lavallee, 2006, The Kruppel-like transcription factor KLF13 is a novel regulator of heart development, EMBO J., 25, 5201, 10.1038/sj.emboj.7601379 Rajamannan, 2007, TGFbeta inducible early gene-1 (TIEG1) and cardiac hypertrophy: discovery and characterization of a novel signaling pathway, J. Cell. Biochem., 100, 315, 10.1002/jcb.21049 Sogawa, 1993, cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2, Nucleic Acids Res., 21, 1527, 10.1093/nar/21.7.1527 Gray, 2002, The Kruppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4, J. Biol. Chem., 277, 34322, 10.1074/jbc.M201304200 Clerk, 2007, Cardiac myocyte gene expression profiling during H2O2-induced apoptosis, Physiol. Genomics, 29, 118, 10.1152/physiolgenomics.00168.2006 Czubryt, 2004, Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy, Recent Prog. Horm. Res., 59, 105, 10.1210/rp.59.1.105 Pikkarainen, 2004, GATA transcription factors in the developing and adult heart, Cardiovasc. Res., 63, 196, 10.1016/j.cardiores.2004.03.025 Xu, 2006, Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice, J. Biol. Chem., 281, 9152, 10.1074/jbc.M510217200 Liang, 2001, The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo, J. Biol. Chem., 276, 30245, 10.1074/jbc.M102174200 Molkentin, 1993, Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo, J. Biol. Chem., 268, 19512, 10.1016/S0021-9258(19)36545-7 Asano, 2000, FKLF-2: a novel Kruppel-like transcriptional factor that activates globin and other erythroid lineage genes, Blood, 95, 3578, 10.1182/blood.V95.11.3578 Song, 1999, RFLAT-1: a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes, Immunity, 10, 93, 10.1016/S1074-7613(00)80010-2 Scohy, 2000, Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family, Genomics, 70, 93, 10.1006/geno.2000.6362 Martin, 2001, Expression of Klf9 and Klf13 in mouse development, Mech. Dev., 103, 149, 10.1016/S0925-4773(01)00343-4 Feng, 2005, The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes, Proc. Natl. Acad. Sci. U. S. A., 102, 9896, 10.1073/pnas.0502041102 Zhang, 2005, A functional screen for Kruppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element, Blood Cells Mol. Dis., 35, 227, 10.1016/j.bcmd.2005.04.009 Ahn, 2007, Dynamic interplay of transcriptional machinery and chromatin regulates “late” expression of the chemokine RANTES in T lymphocytes, Mol. Cell. Biol., 27, 253, 10.1128/MCB.01071-06 Grepin, 1994, A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription, Mol. Cell. Biol., 14, 3115, 10.1128/MCB.14.5.3115 Subramaniam, 1995, Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts, Nucleic Acids Res., 23, 4907, 10.1093/nar/23.23.4907 Subramaniam, 2005, TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro, Mol. Cell. Biol., 25, 1191, 10.1128/MCB.25.3.1191-1199.2005 Subramaniam, 1998, Tissue, cell type, and breast cancer stage-specific expression of a TGF-beta inducible early transcription factor gene, J. Cell. Biochem., 68, 226, 10.1002/(SICI)1097-4644(19980201)68:2<226::AID-JCB9>3.0.CO;2-X Tachibana, 1997, Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells, J. Clin. Invest., 99, 2365, 10.1172/JCI119418 Bensamoun, 2006, TGFbeta inducible early gene-1 knockout mice display defects in bone strength and microarchitecture, Bone, 39, 1244, 10.1016/j.bone.2006.05.021 Tsubone, 2006, Effect of TGF-beta inducible early gene deficiency on flexor tendon healing, J. Orthop. Res., 24, 569, 10.1002/jor.20101 Rosenkranz, 2004, TGF-beta1 and angiotensin networking in cardiac remodeling, Cardiovasc. Res., 63, 423, 10.1016/j.cardiores.2004.04.030 Funnell, 2007, Erythroid Kruppel-like Factor directly activates the basic Kruppel-like Factor gene in erythroid cells, Mol. Cell. Biol., 27, 2777, 10.1128/MCB.01658-06 Davis, 2006, PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells, Mol. Cell. Biol., 26, 2626, 10.1128/MCB.26.7.2626-2636.2006 Owens, 2004, Molecular regulation of vascular smooth muscle cell differentiation in development and disease, Physiol. Rev., 84, 767, 10.1152/physrev.00041.2003 Ross, 1993, The pathogenesis of atherosclerosis: a perspective for the 1990s, Nature, 362, 801, 10.1038/362801a0 Ross, 1999, Atherosclerosis—An inflammatory disease [see comments], N. Engl. J. Med., 340, 115, 10.1056/NEJM199901143400207 Pislaru, 2005, The translation of transcription, Circ. Res., 97, 1083, 10.1161/01.RES.0000194573.70503.b9 Jawien, 1992, Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty, J. Clin. Invest., 89, 507, 10.1172/JCI115613 Ferns, 1991, Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF, Science, 253, 1129, 10.1126/science.1653454 Wei, 2005, Increased neointima formation in cysteine-rich protein 2-deficient mice in response to vascular injury, Circ. Res., 97, 1323, 10.1161/01.RES.0000194331.76925.5c Hoshino, 2000, Regulated expression of the BTEB2 transcription factor in vascular smooth muscle cells: analysis of developmental and pathological expression profiles shows implications as a predictive factor for restenosis, Circulation, 102, 2528, 10.1161/01.CIR.102.20.2528 Nagai, 2005, Significance of the transcription factor KLF5 in cardiovascular remodeling, J. Thromb. Haemost., 3, 1569, 10.1111/j.1538-7836.2005.01366.x Sakamoto, 2003, Smooth muscle cell outgrowth from coronary atherectomy specimens in vitro is associated with less time to restenosis and expression of a key Transcription factor KLF5/BTEB2, Cardiology, 100, 80, 10.1159/000073043 Bafford, 2006, Angiotensin II and tumor necrosis factor-alpha upregulate survivin and Kruppel-like factor 5 in smooth muscle cells: Potential relevance to vein graft hyperplasia, Surgery, 140, 289, 10.1016/j.surg.2006.04.004 Kawai-Kowase, 1999, Transcriptional activation of the zinc finger transcription factor BTEB2 gene by Egr-1 through mitogen-activated protein kinase pathways in vascular smooth muscle cells, Circ. Res., 85, 787, 10.1161/01.RES.85.9.787 Miyamoto, 2003, Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain, Mol. Cell. Biol., 23, 8528, 10.1128/MCB.23.23.8528-8541.2003 Sun, 2001, Intestinal-enriched Kruppel-like factor (Kruppel-like factor 5) is a positive regulator of cellular proliferation, J. Biol. Chem., 276, 6897, 10.1074/jbc.C000870200 Fujiu, 2005, Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5, Circ. Res., 97, 1132, 10.1161/01.RES.0000190613.22565.13 Seo, 2001, Chakravarti, Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein, Cell, 104, 119, 10.1016/S0092-8674(01)00196-9 Dai, 2004, Transcriptional control of epidermal specification and differentiation, Curr. Opin. Genet. Dev., 14, 485, 10.1016/j.gde.2004.07.002 Jaubert, 2003, Ectopic expression of Kruppel-like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier, Development, 130, 2767, 10.1242/dev.00477 Segre, 1999, Klf4 is a transcription factor required for establishing the barrier function of the skin, Nat. Genet., 22, 356, 10.1038/11926 Hamik, 2007, Kruppel-like Factor 4 regulates endothelial inflammation, J. Biol. Chem., 282, 13769, 10.1074/jbc.M700078200 Nakatake, 2006, Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells, Mol. Cell. Biol., 26, 7772, 10.1128/MCB.00468-06 Liu, 2005, Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression, J. Biol. Chem., 280, 9719, 10.1074/jbc.M412862200 King, 2003, Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype, J. Biol. Chem., 278, 11661, 10.1074/jbc.M211337200 Parmacek, 2007, Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation, Circ. Res., 100, 633, 10.1161/01.RES.0000259563.61091.e8 Du, 2003, Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation, Mol. Cell. Biol., 23, 2425, 10.1128/MCB.23.7.2425-2437.2003 Pipes, 2006, The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis, Genes Dev., 20, 1545, 10.1101/gad.1428006 Wang, 2003, Myocardin is a master regulator of smooth muscle gene expression, Proc. Natl. Acad. Sci. U. S. A., 100, 7129, 10.1073/pnas.1232341100 Martin, 2003, Selective modulation of the SM22alpha promoter by the binding of BTEB3 (basal transcription element-binding protein 3) to TGGG repeats, Biochem. J., 375, 457, 10.1042/bj20030870 Uchida, 2000, Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Kruppel-like factor, a novel zinc finger repressor, Mol. Cell. Biol., 20, 7319, 10.1128/MCB.20.19.7319-7331.2000 Gray S, Wang B, Sakuma M, Croce K, Fisch S, Haldar S, et al. Targeting of KLF15 reveals a critical role in the vascular smooth muscle cell response to injury (Abstract). AHA Scientific Sessions 2006; AOP.21.3a: presentation number 1393. Ruiz-Gomez, 1997, Specific muscle identities are regulated by Kruppel during Drosophila embryogenesis, Development, 124, 3407, 10.1242/dev.124.17.3407 Matsumoto, 1998, Cloning the cDNA for a new human zinc finger protein defines a group of closely related Kruppel-like transcription factors, J. Biol. Chem., 273, 28229, 10.1074/jbc.273.43.28229 Yamamoto, 2004, A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2, J. Biol. Chem., 279, 16954, 10.1074/jbc.M312079200