Knockdown of TKTL1 additively complements cisplatin-induced cytotoxicity in nasopharyngeal carcinoma cells by regulating the levels of NADPH and ribose-5-phosphate

Song, 2011, Antitumor and immunoregulatory effects of astragalus on nasopharyngeal carcinoma in vivo and in vitro, Phytother. Res., 25, 909, 10.1002/ptr.3354 Wei, 2005, Nasopharyngeal carcinoma, Lancet, 365, 2041, 10.1016/S0140-6736(05)66698-6 Chen, 2016, Cancer statistics in China, 2015, CA Cancer J. Clin., 66, 115, 10.3322/caac.21338 Hu, 2012, Nanoparticle-based combination therapy toward overcoming drug resistance in cancer, Biochem. Pharmacol., 83, 1104, 10.1016/j.bcp.2012.01.008 Bensouda, 2011, Treatment for metastatic nasopharyngeal carcinoma, Eur. Ann. Otorhinolaryngol., 128, 79, 10.1016/j.anorl.2010.10.003 Lee, 1992, Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976–1985: overall survival and patterns of failure, Int. J. Radiat. Oncol. Biol. Phys., 23, 261, 10.1016/0360-3016(92)90740-9 Lo, 2012, Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches, Semin. Cancer Biol., 22, 79, 10.1016/j.semcancer.2011.12.011 Zhou, 2013, The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer, Biomaterials, 34, 3626, 10.1016/j.biomaterials.2013.01.078 Sherr, 1996, Cancer cell cycles, Science, 274, 1672, 10.1126/science.274.5293.1672 Arlt, 2004, Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells, Mutagenesis, 19, 149, 10.1093/mutage/geh008 Zhang, 2007, Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells, Cancer Lett., 253, 108, 10.1016/j.canlet.2007.01.010 Jackson, 2009, The DNA-damage response in human biology and disease, Nature, 461, 1071, 10.1038/nature08467 Pastore, 2003, Analysis of glutathione, implication in redox and detoxification, Clin. Chim. Acta, 333, 19, 10.1016/S0009-8981(03)00200-6 Bentz, 2011, Lack of transketolase-like (TKTL) 1 aggravates murine experimental colitis, Am. J. Physiol. Gastrointest. Liver Physiol., 300, G598, 10.1152/ajpgi.00323.2010 Semilia, 2015, Expression patterns and prognostic role of transketolase-like 1 in muscle-invasive bladder cancer, World J. Urol., 33, 1403, 10.1007/s00345-014-1473-4 Fritz, 2012, TKTL-1 expression in lung cancer, Pathol. Res. Pract., 208, 203, 10.1016/j.prp.2012.01.007 Krockenberger, 2010, Expression of transketolase-like 1 protein (TKTL1) in human endometrial cancer, Anticancer Res., 30, 1653 Hu, 2007, The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells, Anticancer Drugs, 18, 427, 10.1097/CAD.0b013e328013d99e Hui, 2009, Randomized phase II trial of concurrent cisplatin-radiotherapy with or without neoadjuvant docetaxel and cisplatin in advanced nasopharyngeal carcinoma, J. Clin. Oncol., 27, 242, 10.1200/JCO.2008.18.1545 Phan, 2014, Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies, Cancer Biol. Med., 11, 1 Smith, 2009, Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer, PLoS One, 4, e4961, 10.1371/journal.pone.0004961 Kumar, 2015, Moderate DNA damage promotes metabolic flux into PPP via PKM2 Y-105 phosphorylation: a feature that favours cancer cells, Mol. Biol. Rep., 42, 1317, 10.1007/s11033-015-3876-8 Yu, 2015, TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway, Sci. Rep., 5, 9853, 10.1038/srep09853 Coy, 2005, Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer, Clin. Lab., 51, 257 Boros, 1997, Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation, Cancer Res., 57, 4242 Xu, 2009, Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells, Int. J. Cancer, 124, 1330, 10.1002/ijc.24078 Patra, 2014, The pentose phosphate pathway and cancer, Trends Biochem. Sci., 39, 347, 10.1016/j.tibs.2014.06.005 Chen, 2009, Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer, J. Exp. Clin. Cancer Res., 28, 43, 10.1186/1756-9966-28-43 Vaughn, 2008, Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c, Nat. Cell Biol., 10, 1477, 10.1038/ncb1807