Knee Extensor Strength Does Not Protect Against Incident Knee Symptoms at 30 Months in the Multicenter Knee Osteoarthritis (MOST) Cohort

PM and R - Tập 1 Số 5 - Trang 459-465 - 2009
Neil A. Segal1, James C. Torner2, David T. Felson3, Jingbo Niu3, Leena Sharma4, Cora E. Lewis5, Michael C. Nevitt6
1Department of Orthopaedics and Rehabilitation, University of Iowa, 200 Hawkins Drive, 0728 JPP, Iowa City, IA 52242-1088
2Department of Epidemiology, University of Iowa, Iowa City, IA
3Clinical Epidemiology & Training Unit, Boston University School of Medicine, Boston, MA
4Division of Rheumatology, Feinberg School of Medicine, Chicago, IL
5Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL
6Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA

Tóm tắt

ObjectiveKnee extensor weakness has not been associated consistently with the risk for incident knee pain. Additionally, the balance of hamstring‐to‐quadriceps strength (H:Q ratio) may affect risk and has not been studied. The authors determined whether knee extensor weakness or muscle imbalance is a risk factor for development of frequent knee pain or stiffness and whether the effect is modified by lower limb alignment.DesignObservational study.SettingCommunity.ParticipantsCommunity‐dwelling adults ages 50‐79 years with or at risk of knee osteoarthritis based on obesity, knee injury, or surgery. A total of 1269 knees from women and 1006 knees from men without frequent knee symptoms at baseline and with 15‐ or 30‐ month follow‐up outcome data were included.Assessment of Risk FactorsIsokinetic knee extensor and flexor strength as well as radiographic hip‐knee‐ankle alignment were measured at baseline. H:Q ratio was dichotomized, with normal being considered to be ≥0.6.Main Outcome MeasurementsFrequent knee symptoms at 15‐ or 30‐month follow‐up (frequent knee pain, aching, or stiffness on most days of the past month reported at both telephone contact just before and at visit).ResultsMean ± SD age was 62.2 ± 8.0 years and mean body mass index (BMI) was 30.1 ± 5.4 kg/m2. Mean peak knee extensor strength (KES) was 132.6 ± 42.4 and 76.9 ± 25.3 N·m in men and women, respectively. Approximately 50% of knees in men and 59% of knees in women had an H:Q ratio <0.6. A total of 307 of 2275 eligible knees developed frequent knee symptoms at follow‐up. Logistic regression controlling for age, BMI, femoral neck bone mineral density, activity score, and baseline Kellgren Lawrence grade revealed that neither KES nor H:Q ratio predicted the development of knee symptoms in gender‐stratified or combined analyses. These results were unaffected by adjusting for lower limb alignment.ConclusionsNeither concentric quadriceps strength nor H:Q ratios predicted the development of frequent knee symptoms at 15‐ or 30‐month follow‐up in this cohort.

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PM and R

Tập 1 Số 5

459-465

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