Key targets of hormonal treatment of prostate cancer. Part 1: the androgen receptor and steroidogenic pathways
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bruchovsky N, 1968, The conversion of testosterone to 5‐alpha‐androstan‐17‐beta‐ol‐3‐one by rat prostate in vivo and in vitro, J Biol Chem, 243, 2012, 10.1016/S0021-9258(18)93542-8
Quarmby VE, 1990, Expression and localization of androgen receptor in the R‐3327 Dunning rat prostatic adenocarcinoma, Cancer Res, 50, 735
Colombel M, 1992, Hormone‐regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle, Cancer Res, 52, 4313
Gao J, 2001, Conversion from a paracrine to an autocrine mechanism of androgen‐stimulated growth during maligant transformation of prostate epithelial cells, Cancer Res, 61, 5038
Borner MM, 1995, Drug‐induced apoptosis is not necessarily dependent on macromolecular synthesis or proliferation in the p53‐negative human prostate cancer cell line PC‐3, Cancer Res, 55, 2122
Huggins C, 1941, Studies on prostate cancer. 1 The effects of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate, Cancer Res, 1, 293
Huggins C, 1967, Endocrine‐induced regression of cancers, Cancer Res, 27, 1925
Solit DB, 2002, 17‐Allylamino‐17‐demethoxygeldanamycin induces the degradation of androgen receptor and HER‐2/neu and inhibits the growth of prostate cancer xenografts, Clin Cancer Res, 8, 986
Zegarra‐Morro OL, 2002, Disruption of androgen receptor function inhibits proliferation of androgen‐refractory prostate cancer cells, Cancer Res, 62, 1008
Koivisto P, 1997, Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer, Cancer Res, 57, 314
Taplin ME, 2003, Androgen receptor mutations in androgen‐independent prostate cancer: cancer and leukemia group B study 9663, Cancer Res, 21, 2673
Van Der Kwast ThH, 1991, Androgen receptors in endocrine‐therapy‐resistant human prostate cancer, Int J Med, 48, 189
Linja MJ, 2001, Amplication and overexpression of androgen receptor gene in hormone‐refractory prostate cancer, Cancer Res, 3, 550
Bubendorf L, 1999, Survey of gene amplifications during prostate cancer progression by high‐throughput fluorescence in situ hybridization on tissue microarray, Cancer Res, 59, 803
Gregory CW, 2001, A mechanism for androgen receptor‐mediated prostate cancer recurrence after androgen deprivation therapy, Cancer Res, 61, 4315
Bruchovsky N, 2000, Intermittent androgen suppression for prostate cancer. Canadian Prospective Trial and related observations, Mol Urol, 4, 191
Ruizeveld de Winter JA, 1994, Androgen receptor status in localized and progressive hormone refractory human prostate cancer, Am J Pathol, 144, 735
Gregory CW, 2001, Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen, Cancer Res, 61, 2892
Marcelli M, 2000, Androgen receptor mutations in prostate cancer, Cancer Res, 60, 944
Buchanan G, 2001, Collocation of androgen receptor gene mutations in prostate cancer, Clin Cancer Res, 7, 1273
Koivisto P, 1998, Androgen receptor gene and hormonal therapy failure of prostate cancer, Am J Pathol, 152, 1
Fenton MA, 1997, Functional characterization of mutant androgen receptors from androgen‐independent prostate cancer, Clin Cancer Res, 3, 1383
Culig Z, 1994, Androgen receptor activation in prostatic tumor cell lines by insulin‐like growth factor‐I, keratinocyte growth factor, and epidermal growth factor, Cancer Res, 54, 5474
Geller J, 1985, Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer, Semin Oncol, 12, 28
Craft N, 1999, Evidence for clonal outgrowth of androgen‐independent prostate cancer cells from androgen‐dependent tumors through a two‐step process, Cancer Res, 59, 5030
Nesslinger NJ, 2003, Androgen‐independent growth of LNCaP prostate cancer cells is mediated by gain‐of‐function mutant p53, Cancer Res, 63, 2228
Hobisch A, 1998, Interleukin‐6 regulates prostate‐specific protein expression in prostate carcinoma cells by activation of the androgen receptor, Cancer Res, 58, 4640
Colombel M, 1993, Detection of the apoptosis‐suppressing oncoprotein bc1–2 in hormone‐refractory human prostate cancers, Am J Pathol, 143, 390
Furuya Y, 1996, Expression of bcl‐2 and the progression of human and rodent prostatic cancers, Clin Cancer Res, 2, 389