Keeping an Eye on Crohn’s Disease: Orbital Myositis as the Presenting Symptom

Hindawi Limited - Tập 11 Số 6 - Trang 497-500 - 1997
Carol Durno1, Robert Ehrlich2, Robert E. Taylor2, J. Raymond Buncic2, Peter Hughes2, Anne M. Griffiths3,2
1Division of Gastroenterology and Nutrition, Hospital for Sick Children, University of Toronto, Ontario.
2Gastroenterology Divisions of Gastroenterology and Nutrition, Endocrinology and Opthalmology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario
3Division of Gastroenterology/Clinical Nutrition, 555 University Avenue, Toronto, Ontario M5G 1X8.

Tóm tắt

Episodic periorbital swelling due to presumed orbital inflammation and myositis caused intermittent apparent proptosis and was the presenting symptom of ileocecal Crohn's disease (CD) in a teenage female with a family history of autoimmune disorders and CD. Orbital myositis, a very rare extraintestinal manifestation of inflammatory bowel disease (IBD), likely represents a process of impaired immunoregulation related to the underlying intestinal inflammation. This rare manifestation of IBD simulates the more commonly encountered thyroid orbitopathy (ophthalmopathy), but IBD should be considered if all thyroid tests are negative. It is important to recognize that orbital myositis may be an extraintestinal manifestation of Crohn's disease so that the diagnosis can be made and appropriate therapy commenced.

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