KU-596 decreases mitochondrial superoxide and improves bioenergetics following downregulation of manganese superoxide dismutase in diabetic sensory neurons
Tài liệu tham khảo
Afolayan, 2014, Inducible Hsp70 regulates superoxide dismutase-2 and mitochondrial oxidative stress in the endothelial cells from developing lungs, Am. J. Phys. Lung Cell. Mol. Phys., 306, L351
Akude, 2011, Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats, Diabetes, 60, 288, 10.2337/db10-0818
Bakalova, 2015, Magnetic resonance imaging of mitochondrial dysfunction and metabolic activity, accompanied by overproduction of superoxide, ACS Chem. Neurosci., 6, 1922, 10.1021/acschemneuro.5b00220
Biessels, 2014, Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab), J. Peripher. Nerv. Syst., 19, 77, 10.1111/jns5.12072
Brand, 2011, Assessing mitochondrial dysfunction in cells, Biochem. J., 435, 297, 10.1042/BJ20110162
Calcutt, 2010, Tolerating diabetes – an alternative therapeutic approach for diabetic neuropathy, ASN Neuro., 2, 215, 10.1042/AN20100026
Chen, 2009, Superoxide is the major reactive oxygen species regulating autophagy, Cell Death Differ., 16, 1040, 10.1038/cdd.2009.49
Choi, 2005, Expression of Cu/Zn SOD protein is suppressed in Hsp 70.1 knockout mice, J. Biochem. Mol. Biol., 38, 111
Chowdhury, 2013, The role of aberrant mitochondrial bioenergetics in diabetic neuropathy, Neurobiol. Dis., 51, 56, 10.1016/j.nbd.2012.03.016
Dobrowsky, 2016, Targeting the diabetic chaperome to improve peripheral neuropathy, Curr. Diab. Rep., 16, 71, 10.1007/s11892-016-0769-8
Drew, 2014, Hsp72 is a mitochondrial stress sensor critical for parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle, Diabetes, 63, 1488, 10.2337/db13-0665
Feldman, 2017, New horizons in diabetic neuropathy: mechanisms, bioenergetics, and pain, Neuron, 93, 1296, 10.1016/j.neuron.2017.02.005
Fernyhough, 2015, Mitochondrial dysfunction in diabetic neuropathy: a series of unfortunate metabolic events, Curr. Diab. Rep., 15, 89, 10.1007/s11892-015-0671-9
Higgins, 2014, Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?, Br. J. Pharmacol., 171, 1917, 10.1111/bph.12503
Huang, 2016, Thioredoxin interacting protein (Txnip) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTor signaling pathway, Sci. Rep., 6
Joshi, 2018, Adapting to stress - chaperome networks in cancer, Nat. Rev. Cancer, 18, 562, 10.1038/s41568-018-0020-9
Kim, 2008, Pink1 controls mitochondrial localization of parkin through direct phosphorylation, Biochem. Biophys. Res. Commun., 377, 975, 10.1016/j.bbrc.2008.10.104
Kumar Mv, 2018, Molecular insights into the interaction of Hsp90 with allosteric inhibitors targeting the C-terminal domain, Med. Chem. Commun., 9, 1323, 10.1039/C8MD00151K
Kusuma, 2012, Synthesis and evaluation of novologues as c-terminal hsp90 inhibitors with cytoprotective activity against sensory neuron glucotoxicity, J. Med. Chem., 55, 5797, 10.1021/jm300544c
Lemasters, 2005, Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging, Rejuvenation Res., 8, 3, 10.1089/rej.2005.8.3
Ma, 2014, Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following Ku-32 therapy, J. Pharmacol. Exp. Ther., 348, 281, 10.1124/jpet.113.210435
Ma, 2015, Modulating molecular chaperones improves mitochondrial bioenergetics and decreases the inflammatory transcriptome in diabetic sensory neurons, ACS Chem. Neurosci., 6, 1637, 10.1021/acschemneuro.5b00165
Marcu, 2000, The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone, J. Biol. Chem., 275, 37181, 10.1074/jbc.M003701200
Marine, 2014, Peroxynitrite induced mitochondrial biogenesis following MnSOD knockdown in normal rat kidney (NRK) cells, Redox Biol., 2, 348, 10.1016/j.redox.2014.01.014
McWilliams, 2016, Mito-QC illuminates mitophagy and mitochondrial architecture in vivo, J. Cell Biol., 214, 333, 10.1083/jcb.201603039
McWilliams, 2018, Basal mitophagy occurs independently of pink1 in mouse tissues of high metabolic demand, Cell Metab., 27, 439, 10.1016/j.cmet.2017.12.008
Mori, 2018, A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in ras-activated cancer cells, FEBS J., 10.1111/febs.14671
Ogurtsova, 2017, IDF diabetes Atlas: global estimates for the prevalence of diabetes for 2015 and 2040, Diabetes Res. Clin. Pract., 128, 40, 10.1016/j.diabres.2017.03.024
Pop-Busui, 2016, Inflammation as a therapeutic target for diabetic neuropathies, Curr. Diab. Rep., 16, 29, 10.1007/s11892-016-0727-5
Pratt, 2015, Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases, Annu. Rev. Pharmacol. Toxicol., 55, 353, 10.1146/annurev-pharmtox-010814-124332
Rodina, 2016, The epichaperome is an integrated chaperome network that facilitates tumour survival, Nature, 538, 397, 10.1038/nature19807
Vihervaara, 2014, HSF1 at a glance, J. Cell Sci., 127, 261, 10.1242/jcs.132605
Wang, 2012, ROS-induced mitochondrial depolarization initiates park2/parkin-dependent mitochondrial degradation by autophagy, Autophagy, 8, 1462, 10.4161/auto.21211
Woodford, 2016, Impact of posttranslational modifications on the anticancer activity of Hsp90 inhibitors, Adv. Cancer Res., 129, 31, 10.1016/bs.acr.2015.09.002
Xiao, 2017, Superoxide drives progression of parkin/pink1-dependent mitophagy following translocation of parkin to mitochondria, Cell Death Dis., 8, e3097, 10.1038/cddis.2017.463
Zhang, 2018, Targeting heat shock protein 70 to ameliorate c-jun expression and improve demyelinating neuropathy, ACS Chem. Neurosci., 9, 381, 10.1021/acschemneuro.7b00377
Zhang, 2018, Inhibition of mir-25 aggravates diabetic peripheral neuropathy, Neuroreport, 29, 945, 10.1097/WNR.0000000000001058
Zhang, 2012, A C-terminal heat shock protein 90 inhibitor decreases hyperglycemia-induced oxidative stress and improves mitochondrial bioenergetics in sensory neurons, J. Proteome Res., 11, 129, 10.1021/pr300056m
Zherebitskaya, 2009, Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: Role of glucose-induced oxidative stress, Diabetes, 58, 1356, 10.2337/db09-0034