KLF4 transactivates TRIM29 expression and modulates keratin network

Ma, 2017, KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling, Oncol. Rep., 38, 975, 10.3892/or.2017.5736 Zou, 2019, ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4, Canc. Lett., 467, 19, 10.1016/j.canlet.2019.09.012 Yu, 2011, Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion, Oncogene, 30, 2161, 10.1038/onc.2010.591 Ghaleb, 2017, Krüppel-like factor 4 (KLF4): what we currently know, Gene, 611, 27, 10.1016/j.gene.2017.02.025 Ai, 2014, TRIM29 suppresses TWIST1 and invasive breast cancer behavior, Canc. Res., 74, 4875, 10.1158/0008-5472.CAN-13-3579 Xu, 2020, TRIM29 mediates lung squamous cell carcinoma cell metastasis by regulating autophagic degradation of E-cadherin, Aging (Albany NY), 12, 13488, 10.18632/aging.103451 Du, 2019, MicroRNA-424-5p acts as a potential biomarker and inhibits proliferation and invasion in hepatocellular carcinoma by targeting TRIM29, Life Sci., 224, 1, 10.1016/j.lfs.2019.03.028 Yanagi, 2018, Loss of TRIM29 alters keratin distribution to promote cell invasion in squamous cell carcinoma, Canc. Res., 78, 6795, 10.1158/0008-5472.CAN-18-1495 Chen, 2003, Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation, J. Mol. Biol., 326, 665, 10.1016/S0022-2836(02)01449-3 Yoon, 2005, Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage, Oncogene, 24, 4017, 10.1038/sj.onc.1208576 Xing, 2016, Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract, Nat. Immunol., 17, 1373, 10.1038/ni.3580 Xing, 2017, TRIM29 promotes DNA virus infections by inhibiting innate immune response, Nat. Commun., 8, 945, 10.1038/s41467-017-00101-w Li, 2018, TRIM29 negatively controls antiviral immune response through targeting STING for degradation, Cell Discov., 4, 13, 10.1038/s41421-018-0010-9 Sun, 2020, Loss of TRIM29 suppresses cancer stem cell-like characteristics of PDACs via accelerating ISG15 degradation, Oncogene, 39, 546, 10.1038/s41388-019-0992-2 Windoffer, 2011, Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia, J. Cell Biol., 194, 669, 10.1083/jcb.201008095 Quinn, 2021, Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts, Science, 371 Sawant, 2017, Consequences of keratin phosphorylation for cytoskeletal organization and epithelial functions, Int. Rev. Cell Mol. Biol., 330, 171, 10.1016/bs.ircmb.2016.09.005 Dou, 2019, Identification of the E3 ligase TRIM29 as a critical checkpoint regulator of NK cell functions, J. Immunol., 203, 873, 10.4049/jimmunol.1900171 Xing, 2018, TRIM29 negatively regulates the type I IFN production in response to RNA virus, J. Immunol., 201, 183, 10.4049/jimmunol.1701569 Masuda, Y., et al., TRIM29 Regulates the Assembly of DNA Repair Proteins into Damaged Chromatin. (2041-1723 (Electronic)).