KLF15 controls brown adipose tissue transcriptional flexibility and metabolism in response to various energetic demands

iScience - Tập 25 - Trang 105292 - 2022
Liyan Fan1,2, Alexander F. Lesser1,2, David R. Sweet1,2, Komal S. Keerthy1, Yuan Lu1,3, Ernest R. Chan4, Vinesh Vinayachandran1, Olga Ilkayeva5,6, Tapatee Das7, Christopher B. Newgard5,6,8, Mukesh K. Jain7
1Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA
2Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
3Charles River Laboratories, Ashland, OH 44805, USA
4Institute for Computational Biology, Case Western Reserve University, Cleveland, OH 44106, USA
5Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC 27710, USA
6Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA
7Division of Biology and Medicine, Warren Alpert Medical School of Brown University, Providence, IR 02903, USA
8Department of Medicine and Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA

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