K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

Springer Science and Business Media LLC - Tập 124 Số 3 - Trang 439-447 - 2012
Dong-Anh Khuong-Quang1, Pawel Buczkowicz2, Patricia Rakopoulos2, Xiao-Yang Liu1, Adam M. Fontebasso3, Éric Bouffet4, Ute Bartels4, Steffen Albrecht5, Jeremy Schwartzentruber6, Louis Létourneau6, Mathieu Bourgey6, Guillaume Bourque6, Alexandre Montpetit6, Geneviève Bourret6, Pierre Lepage6, Adam Fleming7, Peter Lichter8, Marcel Kool9, Andreas von Deimling10, Dominik Sturm9, Andrey Korshunov10, Damien Faury7, David Jones9, Jacek Majewski6, Stefan M. Pfister9, Nada Jabado7, Cynthia Hawkins11
1Department of Human Genetics, McGill University, Montreal, QC, Canada
2The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
3Division of Experimental Medicine, McGill University, Montreal, Canada.
4Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada
5Department of Pathology, Montreal Children’s Hospital, McGill University Health Center, Montreal, QC, H1P 2P3, Canada
6McGill University and Genome Quebec Innovation Center, Montreal, Canada
7Department of Paediatrics, Montreal Children’s Hospital, McGill University Health Center, Montreal, QC, H1P 2P3, Canada
8Division of Molecular Genetics, The German Cancer Research Center (DKFZ), Heidelberg, Germany
9Division of Pediatric Neuro-oncology, The German Cancer Research Center (DKFZ), Heidelberg, Germany
10Clinical Cooperation Unit Neuropathology, The German Cancer Research Center (DKFZ), Heidelberg, Germany
11Division of Pathology, The Hospital for Sick Children, Toronto, Canada

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Springer Science and Business Media LLC

Tập 124 Số 3

439-447

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