Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog1Note: Nucleotide sequence data reported in this paper have been submitted to the GenBank data base with the accession number AF 003908.1
Tóm tắt
Từ khóa
Tài liệu tham khảo
Cully, 1994, Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans, Nature, 371, 707, 10.1038/371707a0
Arena, 1995, The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity, J Parasitol, 81, 286, 10.2307/3283936
Rohrer, 1994, Ivermectin binding sites in sensitive and resistant Haemonchus contortus, J Parasitol, 80, 493, 10.2307/3283426
Gottesman, 1993, Biochemistry of multidrug resistance mediated by the multidrug transporter, Ann Rev Biochem, 62, 385, 10.1146/annurev.bi.62.070193.002125
Juliano, 1976, A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants, Biochim Biophys Acta, 455, 152, 10.1016/0005-2736(76)90160-7
Ouellette, 1990, The amplified H circle of methotrexate resistant Leishmania tarentolae contains a novel P-glycoprotein gene, EMBO J, 9, 1027, 10.1002/j.1460-2075.1990.tb08206.x
Ouellet, 1991, Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania, EMBO J, 10, 1009, 10.1002/j.1460-2075.1991.tb08035.x
Hendrickson, 1993, Molecular characterization of the ldmdr1 multidrug resistance gene from Leishmania donovani, Mol Biochem Parasitol, 60, 53, 10.1016/0166-6851(93)90028-V
Legare, 1994, The P-glycoprotein-related gene family in Leishmania, Mol Biochem Parasitol, 68, 81, 10.1016/0166-6851(94)00156-1
Foote, 1994, The mode of action and mechanism of resistance to antimalarial drugs, Acta Trop, 56, 157, 10.1016/0001-706X(94)90061-2
Pussard, 1994, Antimalarial 4-aminoquinolines: mode of action and pharmacokinetics, Fund Clin Pharmacol, 8, 1, 10.1111/j.1472-8206.1994.tb00774.x
Broeks, 1995, A P-glycoprotein protects Caenorhabditis elegans against natural toxins, EMBO J, 14, 1858, 10.1002/j.1460-2075.1995.tb07178.x
Broeks, 1996, Homologue of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans, EMBO J, 15, 6132, 10.1002/j.1460-2075.1996.tb01001.x
Schinkel, 1995, Disruption of the mouse mdr-1a P-glycoprotein gene leads to a deficiency in the blood–brain barrier and to increased sensitivity to drugs, Cell, 77, 491, 10.1016/0092-8674(94)90212-7
Didier, 1996, The abamectin derivative ivermectin is a potent P-glycoprotein inhibitor, Anti-Cancer Drugs, 7, 745, 10.1097/00001813-199609000-00005
Pouliot, 1997, Reversal of P-glycoprotein-associated multidrug resistance by ivermectin, Biochem Pharmacol, 53, 17, 10.1016/S0006-2952(96)00656-9
Wang, 1995, The rate of resistance development by H. contortus to endectocides, 104
Linke, 1992, The P-glycoprotein gene family of Caenorhabditis elegans. Cloning and characterization of genomic and complementary DNA sequences, J Mol Biol, 228, 701, 10.1016/0022-2836(92)90855-E
Higgins, 1988, Clustal: a package for performing multiple sequence alignment on a microcomputer, Gene, 73, 237, 10.1016/0378-1119(88)90330-7
Ausubel, 1987, Northern hybridization of RNA fractionated by agarose-formaldehyde gel electrophoresis, Curr Protoc Mol Biol, 1, 491
Sambrook, 1989, Analysis and cloning of eukaryotic genomic DNA, 916
Blackhall WJ, Liu HY, Xu M, Prichard RK, Beech R. Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus. Submitted 1997.
Conder, 1990, A novel anthelmintic model utilizing jirds, Meriones unguiculatus, infected with Haemonchus contortus, J Parasitol, 76, 168, 10.2307/3283008
Rubio, 1996, The ATP-binding cassette (ABC) gene family of Plasmodium falciparum, Parasitol Today, 12, 135, 10.1016/0169-4758(96)10003-X
Zalis, 1993, Characterization of the pfmdr2 gene for Plasmodium falciparum, Mol Biochem Parasitol, 62, 83, 10.1016/0166-6851(93)90180-6
Rubio, 1994, Plasmodium falciparum: the pfmdr2 protein is not overexpressed in chloroquine-resistant isolates of malaria parasites, Exp Parasitol, 79, 137, 10.1006/expr.1994.1073
Ghosh, 1996, Overexpression of P-glycoprotein gene 1 by transfected Entamoeba histolytica confers emetine-resistance, Mol Biochem Parasitol, 82, 257, 10.1016/0166-6851(96)02733-8
Ince, 1995, A conserved downstream element defines a new class of RNA polymerase II promoters, J Biol Chem, 270, 30249, 10.1074/jbc.270.51.30249
Yusa, 1989, Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells, Cancer Res, 49, 5002
Watanabe, 1995, Comparative study on reversal efficacy of SDZ PSC 833, cyclosporin A and verapamil on multidrug resistance in vitro and in vivo, Acta Oncol, 34, 235, 10.3109/02841869509093961
Conder, 1993, Demonstration of co-resistance of Haemonchus contortus to ivermectin and moxidectin, Vet Rec, 132, 651, 10.1136/vr.132.26.651
Chen, 1986, Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells, Cell, 47, 381, 10.1016/0092-8674(86)90595-7