Isotype-specific immune response to a single hepatitis C virus core epitope defined by a human monoclonal antibody: diagnostic value and correlation to PCR

Akatsuka T, Donets M, Scaglione L, Ching WM, Shih JWK, DeBisceglie AM, Feinstone SM (1993) B-cell epitopes of the hepatitis C virus nucleocapsid protein determined by human monospecific antibodies. Hepatology 18:503–510

Cardoso MS, Jochem H, Hesse R, Epple S, Koerner K, Kubanek B (1992) Evaluating recombinant protein immunoblot assay and polymerase chain reaction for diagnosis of non-A, non-B hepatitis. J Infect Dis 166:450–451

Cardoso MS, Koerner K, Epple S, Kubanek B (1993) Prevalence of HCV-RNA-positive blood donors and correlation to ELISA and RIB A status. Ann Hematol 66:147–151

Cerino A, Boender P, LaMonica N, Rosa C, Habets W, Mondelli MU (1993) A human monoclonal antibody specific for the N terminus of the hepatitis C virus nucleocapsid protein. J Immunol 151:7005–7015

Chiba J, Ohba H, Matsuura Y, Watanabe Y, Katayama T, Kikuchi S, Saito I, Miyamura T (1991) Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant bacculovirus. Proc Natl Acad Sci USA 88:4641–4645

Ching WM, Wychowski C, Beach MJ, Wang H, Davies CL, Carl M, Bradley DW (1992) Interaction of immune sera with synthetic peptides corresponding to the structural protein region of hepatitis C virus. Proc Natl Acad Sci USA 89:3190–3194

Choo QL, Kuo G, Weiner AJ, Overby RL, Bradley DW, Houghton M (1989) Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244:359–362

Choo QL, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, Coit D, Medina-Selby A, Barr PJ, Weiner AJ, Bradley DW, Kuo G, Houghton M (1991) Genetic organisation and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 88:2451–2455

Cristiano K, Di Bisceglie AM, Hoofnagle JH, Feinstone SM (1991) Hepatitis C viral RNA in serum of patients with chronic non-A, non-B hepatitis: detection by the polymerase chain reaction using multiple primer sets. Hepatology 14:51–55

Esteban JI, Gonzalez A, Hernadez JM, Viladomina L, Sanchez C, Lopez-Talavera JC, Lucea D, Martin-Vega C, Vidal X, Esteban R, Guardia J (1990) Evaluation of antibodies to hepatitis C virus in a study of transfusion-associated hepatitis. N Engl J Med 323:1107–1112

Farci P, Alter HJ, Wong D, Miller RH, Shih WJ, Jett B, Purcell RH (1991) A long-term study of hepatitis C virus replication in non-A, non-B hepatitis. N Engl J Med 325:98–104

Ferroni P., Mascolo G, Zaninetti M, Colzani D, Pregliasco F, Pirisi M, Barbone F, Gasparini V (1993) Identification of four epitopes in hepatitis C virus core protein. J Clin Microbiol 31:1586–1591

Follet E, Dow B, McOmish F, Yao P, Hughes W, Mitchell R, Simmonds P (1991) HCV confirmatory testing of blood donors. Lancet 338:1024–1025

Garson JA, Tedder RS, Briggs M, Tuke XP, Glazebrook JA, Trute A, Parker D, Barbara JAJ, Contreras M, Alogsius S (1990a) Detection of hepatitis C viral sequences in blood donations by “nested” polymerase chain reaction and prediction of infectivity. Lancet 335:1419–1422

Garson JA, Tuke PW, Makris M, Briggs M, Machin J-S, Preston FE, Tedder RS (1990b) Demonstration of viremia pattern in haemophiliaes treated with hepatitis-C-virus contaminated factor VIII concentrates. Lancet 336:1022–1025

Hosein B, Fang CT, Popovsky MA, Ye J, Zhang M, Wang CY (1991) Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein. Proc Natl Acad Sci 88:3647–3651

Houghton M, Weiner A, Kuo G, Choo QL (1991) Molecular biology of the hepatitis C virus: implications for diagnosis, development and control of viral diseases. Hepatology 14:381–388

Kou G, Choo QL, Alter HJ, Gitnick GL, Redecker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE, Tegtmeyer GE, Bonino F, Colombo M, Lee WE, Kou G, Berger K, Shuster JR, Overby LR, Bradley DW, Houghton M (1989) An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244:362–364

Leon A, Canton R, Elia M, Mateos M (1991) Second-generation RIBA to confirm diagnosis of HCV infection. Lancet 337:912

Nasoff MS, Zebedee SL, Inchauspe G, Prince AM (1991) Identification of an immunodominant epitope within the capsid protein of hepatitis C virus. Proc Natl Acad Sci USA 88:5462–5466

Okamoto H, Munekata E, Tsuda F, Takahashi K, Yotsumoto S, Tanaka T, Tachibana K, Akahane Y, Sugai Y, Miyakawa Y, Mayumi M (1990) Enzyme-linked immunosorbent assay for antibodies against the capsid protein of hepatitis C virus with a synthetic oligopeptide. Jpn J Exp Med 60:223–233

Sällberg M, Ruden U, Wahren B, Magnius LO (1992) Immune response to a single peptide containing an immunodominant region of hepatitis C virus core protein: the isotypes and the recognition site. Immunol Lett 33:27–34

Siemoneit K, da Silva Cardoso M, Wölpl A, Koerner K, Kubanek B (1994) Isolation and epitope characterization of human monoclonal antibodies to hepatitis C virus core antigen. Hybridoma 13:9–13

Vallari DS, Jett BW, Alter HL, Mimms LT, Holzman R, Shih JW-K (1992) Serological markers of posttransfusion hepatitis C viral infection. J Clin Microbiol 30:552–556

Van der Poel CL, Cuypers HTM, Reesink HW, Weiner AJ, Quan S, Di Nello R, Van Boven JJP, Winkel I, Mulder-Folkerts D, Exel-Oehlers PJ, Schaasberg W, Leentvaar-Kuypers A, Polito A, Houghton M, Lelie PN (1991) Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay. Lancet 337:317–319

Skvaril F (1986) IgG subclasses in viral infections. Monogr Allergy 19:134–143

Weiner AJ, Kou G, Bradley DW, Bonino F, Saracco G, Lee C, Rosenblatt J, Choo QL, Houghton M (1990) Detection of hepatitic C viral sequences in non-A, non-B hepatitis. Lancet 335:1–3

Yatsuhashi H, Inoue O, Koya M, Nagataki S, Mizuno K, Kolberg J, Beall E, Cha T-A, Irvine B, Kuo G, Urdea MS, Yano M (1992) Comparison of hepatitis C virus markers in patients with NANB hepatitis. J Virol Methods 37:13–22

Yokosuka O, Ito Y, Imazeki F, Ohto M, Omata M (1992) Detection of antibody to hepatitis C E2/NS1 protein in patients with type C hepatitis. Biochem Biophys Res Commun 189:565–571

Yoshikawa A, Takahashi K, Kishimoto S, Tsuda F, Akahane Y, Naito S, Tanaka T, Yoshizawa H, Yamasaki M, Okamoto H, Miyakawa Y, Mayumi M (1992) Serodiagnosis of hepatitis C virus infection by ELISA for antibodies against the putative core protein (p20c) expressed inEscherichia coli. J Immunol Methods 148:143–150

Yun Z-B, Lindh G, Weiland O, Johansson B, Sönnerborg A (1993) Detection of hepatitis C virus (HCV) RNA by PCR related to HCV antibodies in serum and liver histology in Swedish blood donors. J Med Virol 39:57–61