Isosalipurposide: A Promising Analgesic, Anti-inflammatory and Gastroprotective Agent Isolated from the Flowers of Acacia cyanophylla

citation_journal_title=Mol Aspects Med; citation_title=Medicinal plants: traditions of yesterday and drugs of tomorrow; citation_author=A Gurib-Fakim; citation_volume=27; citation_publication_date=2006; citation_pages=1-93; citation_doi=10.1016/j.mam.2005.07.008; citation_id=CR1 citation_journal_title=Ecol Soc; citation_title=Development of a compendium of local, wild-harvested species used in the informal economy trade, Cape Town, South Africa; citation_author=LM Petersen, EJ Moll, R Collins, MT Hockings; citation_volume=17; citation_publication_date=2012; citation_pages=26-56; citation_doi=10.5751/ES-04537-170226; citation_id=CR2 Srivastava AK (2018) In: Tewari A, Tiwari S (ed) Significance of medicinal plants in human life, 1st edn. Elsevier Ltd citation_journal_title=Mol Plant; citation_title=UVR8 mediates UV-B-induced Arabidopsis defense responses against Botrytis cinerea by controlling sinapate accumulation; citation_author=PV Demkura, CL Ballaré; citation_volume=5; citation_publication_date=2012; citation_pages=642-652; citation_doi=10.1093/mp/sss025; citation_id=CR4 citation_journal_title=Fitoterepia; citation_title=Anti-inflammatory and analgesic activities of Zizyphus lotus root barks; citation_author=W Borgi, K Ghedira, N Chouchane; citation_volume=78; citation_publication_date=2007; citation_pages=16-19; citation_doi=10.1016/j.fitote.2006.09.010; citation_id=CR5 citation_journal_title=Drug Discov Today; citation_title=Plant-derived compounds in clinical trials; citation_author=A Saklani, SK Kutty; citation_volume=13; citation_publication_date=2008; citation_pages=161-171; citation_doi=10.1016/j.drudis.2007.10.010; citation_id=CR6 citation_journal_title=Clin Transl Oncol; citation_title=Therapeutic potential of natural products in glioblastoma treatment: targeting key glioblastoma signaling pathways and epigenetic alterations; citation_author=MN Abbas, S Kausar, H Cui; citation_volume=22; citation_publication_date=2020; citation_pages=963-977; citation_doi=10.1007/s12094-019-02227-3; citation_id=CR7 citation_journal_title=Food Chem; citation_title=Semi-synthesis of new antimicrobial esters from the natural oleanolic and maslinic acids; citation_author=K Chouaïb, F Hichri, A Nguir, M Daami-Remadi, N Elie, D Touboul, H Ben Jannet, MH Hamza; citation_volume=183; citation_publication_date=2015; citation_pages=8-17; citation_doi=10.1016/j.foodchem.2015.03.018; citation_id=CR8 citation_journal_title=Eur J Med Chem; citation_title=A review of anti-infective and anti-inflammatory chalcones; citation_author=Z Nowakowska; citation_volume=42; citation_publication_date=2007; citation_pages=125-137; citation_doi=10.1016/j.ejmech.2006.09.019; citation_id=CR9 citation_journal_title=Genes Nutr; citation_title=Dietary chalcones with chemopeventive and chemoterapeutic potential; citation_author=B Orlikova, D Tasdemir, F Golais, M Dicato, M Diederich; citation_volume=6; citation_publication_date=2011; citation_pages=125-147; citation_doi=10.1007/s12263-011-0210-5; citation_id=CR10 citation_journal_title=Eur J Med Chem; citation_title=Chalcone scaffolds as anti-infective agents: structural and molecular target perspectives; citation_author=KD Mahapatra, KS Bharti, V Asati; citation_volume=101; citation_publication_date=2015; citation_pages=496-524; citation_doi=10.1016/j.ejmech.2015.06.052; citation_id=CR11 citation_journal_title=Bioorg Chem; citation_title=Promising anti-inflammatory effects of chalcones via inhibition of cyclooxygenase, prostaglandin E2, inducible NO synthase and nuclear factor κB activities; citation_author=H Rashid, X Yiming, N Ahmad, Y Muhammad, L Wang; citation_volume=87; citation_publication_date=2019; citation_pages=335-365; citation_doi=10.1016/j.bioorg.2019.03.033; citation_id=CR12 citation_journal_title=Eur J Med Chem; citation_title=Anti-cancer chalcones: Structural and molecular target perspectives; citation_author=DK Mahapatra, SK Bharti, V Asati; citation_volume=98; citation_publication_date=2015; citation_pages=69-114; citation_doi=10.1016/j.ejmech.2015.05.004; citation_id=CR13 citation_journal_title=Phytochem Rev; citation_title=An overview on genus garcinia: phytochemical and therapeutical aspects; citation_author=M Hemshekhar, K Sunitha, MS Santhosh, S Devaraja, K Kemparaju, BS Vishwanath, SR Niranjana, KS Girish; citation_volume=10; citation_publication_date=2011; citation_pages=325-351; citation_doi=10.1007/s11101-011-9207-3; citation_id=CR14 citation_journal_title=Phytomedicine; citation_title=Plant derived therapeutics for the treatment of leishmaniasis; citation_author=R Sen, M Chatterjee; citation_volume=18; citation_publication_date=2011; citation_pages=1056-1069; citation_doi=10.1016/j.phymed.2011.03.004; citation_id=CR15 citation_journal_title=Lipids Health Dis; citation_title=Minor lipid components of some Acacia Species: potential dietary health benefits of the unexploited seeds; citation_author=N Nasri, W Elfalleh, N Tlili, H Hannachi, S Triki, A Khaldi; citation_volume=11; citation_publication_date=2012; citation_pages=49; citation_doi=10.1186/1476-511X-11-49; citation_id=CR16 citation_journal_title=Saudi J Biol Sci; citation_title=Medicinal plants used in Jeddah, Saudi Arabia: phytochemical screening; citation_author=A Alqethami, YA Aldhebian; citation_volume=28; citation_publication_date=2021; citation_pages=805-812; citation_doi=10.1016/j.sjbs.2020.11.013; citation_id=CR17 citation_journal_title=Ind Crops Prod; citation_title=Extraction, identification and studies of Isosalipurposide a natural chalcone dye from Acacia cyanophylla flowers on wool; citation_author=H Ghouila, N Meksi, W Haddar, MF Mhenni, H Ben Jannet; citation_volume=35; citation_publication_date=2012; citation_pages=31-36; citation_doi=10.1016/j.indcrop.2011.05.026; citation_id=CR18 citation_journal_title=Asian Pac J Trop Biomed; citation_title=Antioxidant and anti-acetylcholinesterase activities of extracts and secondary metabolites from Acacia cyanophylla; citation_author=L Ghribi, H Ghouila, A Omri, M Besbes, H Ben Jannet; citation_volume=4; citation_publication_date=2014; citation_pages=417-423; citation_doi=10.12980/APJTB.4.2014C1038; citation_id=CR19 citation_journal_title=Toxicol Appl Pharmacol; citation_title=The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation; citation_author=YJ Han, SS Cho, HJ Yang, MK Kim, HC Jang, ED Park, SJ Bang, SY Jung, HS Ki; citation_volume=287; citation_publication_date=2015; citation_pages=77-85; citation_doi=10.1016/j.taap.2015.05.015; citation_id=CR20 Onaolapo AY, Onaolapo OJ (2019) In: Grumezescu AM, Holban AM (ed) Herbal beverages and brain function in health and disease, 1st edn. Elsevier Inc citation_journal_title=Mol Divers; citation_title=Synthesis and biological evaluation of glycosides containing triazene-chalcones; citation_author=Q Lei, S Zhang, M Liu, J Li, X Zhang, Y Long; citation_volume=21; citation_publication_date=2017; citation_pages=957-966; citation_doi=10.1007/s11030-017-9768-1; citation_id=CR22 citation_journal_title=Curr Org Chem; citation_title=Isoflavones, their glycosides and glycoconjugates. Synthesis and biological activity; citation_author=S Wieslaw, G Grzegorz, R Aleksandra; citation_volume=21; citation_publication_date=2017; citation_pages=218-235; citation_id=CR23 citation_journal_title=Int J Biol Macromol; citation_title=Physico-chemical characterization and pharmacological activities of sulfated polysaccharide from sea urchin, Paracentrotus lividus; citation_author=YB Salem, S Amri, KM Hammi, A Abdelhamid, D Cerf, A Bouraoui, H Majdoub; citation_volume=97; citation_publication_date=2017; citation_pages=8-15; citation_doi=10.1016/j.ijbiomac.2017.01.007; citation_id=CR24 citation_journal_title=BMC Complement Altern Med; citation_title=Scientific investigation of crude alkaloids from medicinal plants for the management of pain; citation_author=M Shoaib, AWS Shah, N Ali, I Shah, S Ullah, M Ghias, NM Tahir, F Gul, S Akhtar, A Ullah, W Akbar, A Ullah; citation_volume=16; citation_publication_date=2016; citation_pages=78-186; citation_doi=10.1186/s12906-016-1041-0; citation_id=CR25 citation_journal_title=J Ethnopharmacol; citation_title=Anti-inflammatory activity and gastroprotective effect of Hertia cheirifolia L. roots extract; citation_author=K Majouli, A Hamdi, A Abdelhamid, A Bouraoui, A Kenani; citation_volume=217; citation_publication_date=2018; citation_pages=7-10; citation_doi=10.1016/j.jep.2018.02.010; citation_id=CR26 citation_journal_title=Curr Top Med Chem; citation_title=Chalcone derivatives: anti-inflammatory potential and molecular targets perspectives; citation_author=KM Debarshi, KB Sanjay, A Vivek; citation_volume=17; citation_publication_date=2017; citation_pages=3146-3169; citation_doi=10.2174/1568026617666170914160446; citation_id=CR27 citation_journal_title=Bioorg Med Chem Lett; citation_title=Screening of chalcone analogs with anti-depressant, anti-inflammatory, analgesic, and COX-2-inhibiting effects; citation_author=ZH Huang, LQ Yin, LP Guan, ZH Li, C Tan; citation_volume=30; citation_publication_date=2020; citation_pages=127173; citation_doi=10.1016/j.bmcl.2020.127173; citation_id=CR28 citation_journal_title=J Pharmacol Exp Ther; citation_title=Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo; citation_author=PN Yadav, WK Kroeze, MS Farrell, BL Roth; citation_volume=339; citation_publication_date=2011; citation_pages=99-105; citation_doi=10.1124/jpet.111.183780; citation_id=CR29 citation_journal_title=Fed Proc; citation_title=Pathway to carrageenan-induced inflammation of the hind limb of the rat; citation_author=R Vinegar, JF Truax, JL Selph, PR Johnston, AL Venable, KK McKenzie; citation_volume=46; citation_publication_date=1987; citation_pages=118-126; citation_id=CR30 citation_journal_title=J Ethnopharmacol; citation_title=Oral anti-inflammatory and anti-ulcerogenic activities of hydroalcoholic extract and partitioned fractions of Turnera ulmifolia (Turneraceae); citation_author=MA Antonio, ARM Souza-Brito; citation_volume=61; citation_publication_date=1998; citation_pages=215-228; citation_doi=10.1016/S0378-8741(98)00049-X; citation_id=CR31 citation_journal_title=Molecules; citation_title=Analgesic potential of essential oils; citation_author=JF Sarmento-Neto, NL Gomes, CF Bezerra Felipe, DP Sousa; citation_volume=21; citation_publication_date=2016; citation_pages=20-49; citation_doi=10.3390/molecules21010020; citation_id=CR32 citation_journal_title=Phytomedicine; citation_title=Analgesic and anti-inflammatory effects of chalcones isolated from Myracrodruon urundeuva Allemào; citation_author=GSB Viana, MAM Bandeira, FJA Matos; citation_volume=10; citation_publication_date=2003; citation_pages=189-195; citation_doi=10.1078/094471103321659924; citation_id=CR33 citation_journal_title=Best Pract Res Clin Gastroenterol; citation_title=Pathogenesis of NSAID-induced gastroduodenal mucosal injury; citation_author=JL Wallace; citation_volume=15; citation_publication_date=2001; citation_pages=691-703; citation_doi=10.1053/bega.2001.0229; citation_id=CR34 citation_journal_title=Molecules; citation_title=Preventative and therapeutic potential of flavonoids in peptic ulcers; citation_author=W Zhang, Z Lai, Y Lian, Q Li, L Sun, R Chen, X Lai, E Yuan, S Sun; citation_volume=25; citation_publication_date=2020; citation_pages=4626-4657; citation_doi=10.3390/molecules25204626; citation_id=CR35 citation_journal_title=J Ethnopharmacol; citation_title=Gastroprotective effect of ethanol extracts of cladodes and roots of Pilosocereus gounellei (A. Weber ex K. Schum.) Bly. Ex Rowl (Cactaceae) on experimental ulcer models; citation_author=GA Sousa, IS Oliveira, FV Silva-Freitas, AFSC Viana, BPS Neto, FVM Cunha, RLG Gonçalves, MPM Amaral, RCM Oliveira, PD Fernandes, JKS Maciel, TMS Silva, MFV Souza, FA Oliveira; citation_volume=218; citation_publication_date=2018; citation_pages=100-108; citation_doi=10.1016/j.jep.2018.02.009; citation_id=CR36