Iron preparations for women of reproductive age with iron deficiency anaemia in pregnancy (FRIDA): a systematic review and network meta-analysis

The Lancet Haematology - Tập 8 - Trang e503-e512 - 2021
Ewelina Rogozińska1, Jahnavi Daru2, Marios Nicolaides3, Carmen Amezcua-Prieto4, Susan Robinson5, Rui Wang6, Peter J Godolphin1, Carlos Martín Saborido7, Javier Zamora8,9, Khalid S Khan4, Shakila Thangaratinam8
1MRC Clinical Trials Unit at UCL, University College London, London, UK
2Institute for Population Health Science, Queen Mary University of London, London, UK
3Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK
4Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain
5Department of Haematology, Guy's and St Thomas' Hospital, London, UK
6Department of Obstetrics and Gynaecology, Monash University, Melbourne, VIC, Australia
7Department of Health Planning and Economics, National School of Public Health, Institute of Health Carlos III, Madrid, Spain
8Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
9Hospital Universitario Ramón y Cajal (IRYCIS), CIBERESP, Madrid, Spain

Tài liệu tham khảo

Ganz, 2013, Systemic iron homeostasis, Physiol Rev, 93, 1721, 10.1152/physrev.00008.2013 Barroso, 2011, Prevalence of maternal anaemia and its predictors: a multi-centre study, Eur J Obstet Gynecol Reprod Biol, 159, 99, 10.1016/j.ejogrb.2011.07.041 Daru, 2018, Risk of maternal mortality in women with severe anaemia during pregnancy and post partum: a multilevel analysis, Lancet Glob Health, 6, e548, 10.1016/S2214-109X(18)30078-0 Stevens, 2013, Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data, Lancet Glob Health, 1, e16, 10.1016/S2214-109X(13)70001-9 Smith, 2019, Maternal and perinatal morbidity and mortality associated with anemia in pregnancy, Obstet Gynecol, 134, 1234, 10.1097/AOG.0000000000003557 Garcia-Casal, 2019, Use and interpretation of hemoglobin concentrations for assessing anemia status in individuals and populations: results from a WHO technical meeting, Ann N Y Acad Sci, 1450, 5, 10.1111/nyas.14090 Daru, 2019, Revisiting the basis for haemoglobin screening in pregnancy, Curr Opin Obstet Gynecol, 31, 388, 10.1097/GCO.0000000000000580 Auerbach, 2020, Intravenous iron: a framework for changing the management of iron deficiency, Lancet Haematol, 7, e342, 10.1016/S2352-3026(19)30264-9 Milman, 2005, Iron prophylaxis during pregnancy—how much iron is needed? A randomized dose-response study of 20–80 mg ferrous iron daily in pregnant women, Acta Obstet Gynecol Scand, 84, 238, 10.1111/j.0001-6349.2005.00610.x Peña-Rosas, 2015, Daily oral iron supplementation during pregnancy, Cochrane Database Syst Rev, 7 Reveiz, 2011, Treatments for iron-deficiency anaemia in pregnancy, Cochrane Database Syst Rev, 10 Al, 2005, Intravenous versus oral iron for treatment of anemia in pregnancy: a randomized trial, Obstet Gynecol, 106, 1335, 10.1097/01.AOG.0000185260.82466.b4 Bayoumeu, 2002, Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route, Am J Obstet Gynecol, 186, 518, 10.1067/mob.2002.121894 Khalafallah, 2015, Treatment of iron deficiency anaemia of late pregnancy with a single intravenous iron polymaltose or ferric carboxymaltose versus oral iron sulphate: a prospective randomized controlled study (tidal), Haematologica, 100, 131 Froessler, 2013, Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial, J Matern Fetal Neonatal Med, 26, 654, 10.3109/14767058.2012.746299 Aggarwal, 2012, Evaluation of iron sucrose and oral iron in management of iron deficiency anaemia in pregnancy, Natl J Community Med, 3, 55 Guyatt, 2011, GRADE guidelines: 8. Rating the quality of evidence—indirectness, J Clin Epidemiol, 64, 1303, 10.1016/j.jclinepi.2011.04.014 Nikolakopoulou, 2020, CINeMA: an approach for assessing confidence in the results of a network meta-analysis, PLoS Med, 17, 10.1371/journal.pmed.1003082 Salanti, 2014, Evaluating the quality of evidence from a network meta-analysis, PLoS One, 9, 10.1371/journal.pone.0099682 Malinowski, 2019, Reported outcomes in perinatal iron deficiency anemia trials: a systematic review, Gynecol Obstet Invest, 84, 417, 10.1159/000495566 DerSimonian, 2007, Random-effects model for meta-analysis of clinical trials: an update, Contemp Clin Trials, 28, 105, 10.1016/j.cct.2006.04.004 Harville, 1977, Maximum likelihood approaches to variance component estimation and to related problems, J Am Stat Assoc, 72, 320, 10.1080/01621459.1977.10480998 Higgins, 2002, Quantifying heterogeneity in a meta-analysis, Stat Med, 21, 1539, 10.1002/sim.1186 Liu, 2016, Epley and Semont maneuvers for posterior canal benign paroxysmal positional vertigo: a network meta-analysis, Laryngoscope, 126, 951, 10.1002/lary.25688 Dias, 2010, Checking consistency in mixed treatment comparison meta-analysis, Stat Med, 29, 932, 10.1002/sim.3767 Caldwell, 2010, Mixed treatment comparison analysis provides internally coherent treatment effect estimates based on overviews of reviews and can reveal inconsistency, J Clin Epidemiol, 63, 875, 10.1016/j.jclinepi.2009.08.025 Efthimiou, 2016, GetReal in network meta-analysis: a review of the methodology, Res Synth Methods, 7, 236, 10.1002/jrsm.1195 Chaimani, 2013, Graphical tools for network meta-analysis in STATA, PLoS One, 8, 10.1371/journal.pone.0076654 al-Momen, 1996, Intravenous iron sucrose complex in the treatment of iron deficiency anemia during pregnancy, Eur J Obstet Gynecol Reprod Biol, 69, 121, 10.1016/0301-2115(95)02538-3 Arzoo, 2020, Iron deficiency anemia in pregnancy: intravenous iron sucrose versus oral iron sulfate, Bangladesh J Obstet Gynecol, 33, 40, 10.3329/bjog.v33i1.43541 Borg, 2020, A comparative study between lactoferrin versus ferrous sulfate in iron-deficiency during pregnancy, QJM, 113 Dalal, 2018, Oral versus intravenous iron for treatment of iron deficiency anaemia in pregnancy: a randomized controlled trial, Indian J Public Health Res Dev, 9, 1, 10.5958/0976-5506.2018.00513.2 Darwish, 2019, Lactoferrin plus health education versus total dose infusion (TDI) of low-molecular weight (LMW) iron dextran for treating iron deficiency anemia (IDA) in pregnancy: a randomized controlled trial, J Matern Fetal Neonatal Med, 32, 2214, 10.1080/14767058.2018.1429396 Darwish, 2019, Total dose iron dextran infusion versus oral iron for treating iron deficiency anemia in pregnant women: a randomized controlled trial, J Matern Fetal Neonatal Med, 32, 398, 10.1080/14767058.2017.1379988 Gawai, 2020, A randomized controlled trial on lactoferrin versus ferrous sulphate for the treatment of mild to moderate iron deficiency anaemia in pregnancy, Int J Reprod Contracept Obstet Gynecol, 9, 562, 10.18203/2320-1770.ijrcog20200336 Han, 2011, Moderate NaFeEDTA and ferrous sulfate supplementation can improve both hematologic status and oxidative stress in anemic pregnant women, Asia Pac J Clin Nutr, 20, 514 Hayat, 2019, A randomized control trial to assess the efficacy and safety of iron dextran and iron sucrose among IDA affected pregnant women, Indo Am J Pharm Sci, 6, 7681 Khalafallah, 2010, A prospective randomized, controlled trial of intravenous versus oral iron for moderate iron deficiency anaemia of pregnancy, J Intern Med, 268, 286, 10.1111/j.1365-2796.2010.02251.x Komolafe, 2003, A comparative study between intramuscular iron dextran and oral ferrous sulphate in the treatment of iron deficiency anaemia in pregnancy, J Obstet Gynaecol, 23, 628, 10.1080/01443610310001604394 Kumar, 2005, Oral versus high dose parenteral iron supplementation in pregnancy, Int J Gynaecol Obstet, 89, 7, 10.1016/j.ijgo.2005.01.016 Ma, 2010, Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women, Br J Nutr, 104, 1655, 10.1017/S000711451000259X Mehta, 2014, Iron deficiency anemia in pregnancy: intravenous versus oral route, Natl J Community Med, 5, 10 Menendez, 1994, The effects of iron supplementation attendants, given by traditional birth attendants, on the prevalence of anaemia and malaria, Trans R Soc Trop Med Hyg, 88, 590, 10.1016/0035-9203(94)90176-7 Neogi, 2019, Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3, randomised, controlled trial, Lancet Glob Health, 7, e1706, 10.1016/S2214-109X(19)30427-9 Preziosi, 1997, Effect of iron supplementation on the iron status of pregnant women: consequences for newborns, Am J Clin Nutr, 66, 1178, 10.1093/ajcn/66.5.1178 Rajwani, 2020, Randomized clinical trial of IV iron sucrose and IV ferric carboxymaltose in the treatment of moderate iron deficiency anaemia in pregnancy, Int J Res Pharm Sci, 11, 4937, 10.26452/ijrps.v11i3.2796 Sagaonkar, 2009, Pregnancy induced iron deficiency and the evaluation and comparison of the efficacy and safety of ferrous fumarate and carbonyl iron in its treatment—PERFECT trial, J Obstet Gynaecol India, 59, 552 Samsudin, 2020, Safety and efficacy of intravenous iron sucrose versus low molecular weight iron dextran for treatment of iron deficiency anemia in pregnancy: a randomized controlled trial, Int J Womens Health, 12, 1259, 10.2147/IJWH.S281826 Santiago M, Olivar J, Reyes L. Comparison of the efficacy of iron amino acid chelate and ferrous sulfate in the treatment of iron deficiency anemia among pregnant women seen at out patient department of a tertiary hospital. 14th World Congress of Perinatal Medicine; Istanbul, Turkey; Sept 11–14, 2019 (O1024). Sharma, 2004, A prospective, partially randomized study of pregnancy outcomes and hematologic responses to oral and intramuscular iron treatment in moderately anemic pregnant women, Am J Clin Nutr, 79, 116, 10.1093/ajcn/79.1.116 Simmons, 1993, Evaluation of a gastric delivery system for iron supplementation in pregnancy, Am J Clin Nutr, 58, 622, 10.1093/ajcn/58.5.622 Singh, 1998, A comparison between intravenous iron polymaltose complex (Ferrum Hausmann) and oral ferrous fumarate in the treatment of iron deficiency anaemia in pregnancy, Eur J Haematol, 60, 119, 10.1111/j.1600-0609.1998.tb01008.x Suharno, 1993, Supplementation with vitamin A and iron for nutritional anaemia in pregnant women in West Java, Indonesia, Lancet, 342, 1325, 10.1016/0140-6736(93)92246-P Sun, 2010, A combination of iron and retinol supplementation benefits iron status, IL-2 level and lymphocyte proliferation in anemic pregnant women, Asia Pac J Clin Nutr, 19, 513 Tanumihardjo, 2002, Vitamin A and iron status are improved by vitamin A and iron supplementation in pregnant Indonesian women, J Nutr, 132, 1909, 10.1093/jn/132.7.1909 Van Eijk, 1978, Serum ferritin and iron stores during pregnancy, Clin Chim Acta, 83, 81, 10.1016/0009-8981(78)90210-3 Nanthini, 2017, Kavitha. A comparative prospective study to assess the efficacy and safety of iron sucrose versus iron sorbitol citric acid in pregnant women with iron deficiency anemia in a tertiary care hospital, Natl J Physiol Pharm Pharmacol, 7, 545 Ruangvutilert, 2017, Low-Dose weekly intravenous iron sucrose versus daily oral iron for iron deficiency anemia in late pregnancy: a randomized controlled trial, J Med Assoc Thai, 100, 496 Abhilashini, 2014, Intravenous iron sucrose and oral iron for the treatment of iron deficiency anaemia in pregnancy, J Clin Diagn Res, 8, OC04 Bhavi, 2017, Intravenous iron sucrose v/s oral ferrous fumarate for treatment of anemia in pregnancy. A randomized controlled trial, BMC Pregnancy Childbirth, 17, 137, 10.1186/s12884-017-1313-9 Breymann, 2017, Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP), J Perinat Med, 45, 443, 10.1515/jpm-2016-0050 Shafi, 2012, Iron deficiency anemia in pregnancy: intravenous versus oral route, J Obstet Gynaecol India, 62, 317, 10.1007/s13224-012-0222-0 Digumarthi, 2008, Comparison of intravenous versus oral iron in iron deficiency anaemia of pregnancy (FC5.02), BJOG, 115, 53 Gupta, 2014, A randomised controlled trial to compare intravenous iron sucrose and oral iron in treatment of iron deficiency anemia in pregnancy, Indian J Hematol Blood Transfus, 30, 120, 10.1007/s12288-012-0224-1 Nappi, 2009, Efficacy and tolerability of oral bovine lactoferrin compared to ferrous sulfate in pregnant women with iron deficiency anemia: a prospective controlled randomized study, Acta Obstet Gynecol Scand, 88, 1031, 10.1080/00016340903117994 Neeru, 2012, Iron sucrose versus oral iron therapy in pregnancy anemia, Indian J Community Med, 37, 214, 10.4103/0970-0218.103467 Rezk, 2016, Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: a randomized clinical trial, J Matern Fetal Neonatal Med, 29, 1387, 10.3109/14767058.2015.1049149 Dhanani, 2012, Comparison of efficacy and safety of two parenteral iron preparations in pregnant women, J Pharmacol Pharmacother, 3, 314, 10.4103/0976-500X.103688 Fochi, 1985, Efficacy of iron therapy: a comparative evaluation of four iron preparations administered to anaemic pregnant women, J Int Med Res, 13, 1, 10.1177/030006058501300101 Jose, 2019, Comparison of ferric carboxymaltose and iron sucrose complex for treatment of iron deficiency anemia in pregnancy—randomised controlled trial, BMC Pregnancy Childbirth, 19, 54, 10.1186/s12884-019-2200-3 Kamdi, 2015, Efficacy and safety of ferrous asparto glycinate in the management of iron deficiency anaemia in pregnant women, J Obstet Gynaecol, 35, 4, 10.3109/01443615.2014.930098 Kochhar, 2013, Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial, J Obstet Gynaecol Res, 39, 504, 10.1111/j.1447-0756.2012.01982.x Ortiz, 2011, Efficacy and safety of oral iron(III) polymaltose complex versus ferrous sulfate in pregnant women with iron-deficiency anemia: a multicenter, randomized, controlled study, J Matern Fetal Neonatal Med, 24, 1347, 10.3109/14767058.2011.599080 Paesano, 2010, Lactoferrin efficacy versus ferrous sulfate in curing iron disorders in pregnant and non-pregnant women, Int J Immunopathol Pharmacol, 23, 577, 10.1177/039463201002300220 Rudra, 2016, Comparison of intravenous iron sucrose with oral iron in pregnant women with iron deficiency anaemia, Int J Reprod Contracept Obstet Gynecol, 5, 747, 10.18203/2320-1770.ijrcog20160577 Singh, 2013, A study to compare the efficacy and safety of intravenous iron sucrose and intramuscular iron sorbitol therapy for anemia during pregnancy, J Obstet Gynaecol India, 63, 18, 10.1007/s13224-012-0248-3 Tariq, 2015, Parenteral iron therapy in the treatment of iron deficiency anemia during pregnancy: a randomized controlled trial, J Coll Physicians Surg Pak, 25, 193 Symonds, 1969, Controlled-release iron therapy in pregnancy, Aust N Z J Obstet Gynaecol, 9, 21, 10.1111/j.1479-828X.1969.tb02520.x Pavord, 2020, UK guidelines on the management of iron deficiency in pregnancy, Br J Haematol, 188, 819, 10.1111/bjh.16221 Lin, 2019, Borrowing of strength from indirect evidence in 40 network meta-analyses, J Clin Epidemiol, 106, 41, 10.1016/j.jclinepi.2018.10.007 2016 Moller, 2017, Early antenatal care visit: a systematic analysis of regional and global levels and trends of coverage from 1990 to 2013, Lancet Glob Health, 5, e977, 10.1016/S2214-109X(17)30325-X Haider, 2013, Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis, BMJ, 346, 10.1136/bmj.f3443 Peña-Rosas, 2015, Intermittent oral iron supplementation during pregnancy, Cochrane Database Syst Rev, 10 Qassim, 2018, Safety and efficacy of intravenous iron polymaltose, iron sucrose and ferric carboxymaltose in pregnancy: a systematic review, Aust N Z J Obstet Gynaecol, 58, 22, 10.1111/ajo.12695 Daru, 2016, Systematic review of randomized trials of the effect of iron supplementation on iron stores and oxygen carrying capacity in pregnancy, Acta Obstet Gynecol Scand, 95, 270, 10.1111/aogs.12812 Daru, 2019, Iron interventions in pregnancy and better clinical outcomes: the jury is out, Lancet Glob Health, 7, e1597, 10.1016/S2214-109X(19)30468-1 Stoffel, 2020, Iron absorption from supplements is greater with alternate day than with consecutive day dosing in iron-deficient anemic women, Haematologica, 105, 1232, 10.3324/haematol.2019.220830